Projects funded by the NCN
L-asparaginase resistance in childhood ALL with IKZF1, TP53, BCR-ABL1 and iAMP21 alterations.
2014/13/N/NZ5/03660
Keywords:
resistance L-Asparaginase acute lymphoblastic leukaemia children
Descriptors:
- NZ5_5: Diagnostics in human diseases
- NZ5_1: Etiology of human diseases
Panel:
NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution :
Uniwersytet Medyczny w Łodzi, Wydział Lekarski
woj. łódzkie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 7 - announced on 2014-03-17
Amount awarded: 149 750 PLN
Project start date (Y-m-d): 2015-02-25
Project end date (Y-m-d): 2019-02-24
Project duration:: 48 months (the same as in the proposal)
Project status: Project settled
Information in the final report
- Publication in academic press/journals (2)
- Gene expression of ASNS, LGMN and CTSB is elevated in a subgroup of childhood BCP-ALL with PAX5 deletion.Authors:Ewa Wrona1, Justyna Jakubowska1, Bartosz Pawlik1, Agata Pastorczak1, Joanna Madzio1, Monika Lejman2, Łukasz Sędek3, Jerzy Kowalczyk2, Tomasz Szczepański3, Wojciech Młynarski1Academic press:Oncology Letters (rok: 2019, tom: 18, strony: 6926-6932), Wydawca: Spandidos PublicationsStatus:PublishedDOI:10.3892/ol.2019.11046 - link to the publication
- MLPA as a complementary tool for diagnosis of chromosome 21 aberrations in childhood BCP-ALLAuthors:Ewa Wrona1, Marcin Braun2, Agata Pastorczak1, Joanna Taha1, Monika Lejman3, Jerzy Kowalczyk3, Wojciech Fendler4,5, Wojciech Młynarski1Academic press:Journal of Applied Genetics (rok: 2019, tom: 60, strony: 347-355), Wydawca: Springer NatureStatus:PublishedDOI:10.1007/s13353-019-00509-8. - link to the publication