Projects funded by the NCN
Heterogeneity immunocompetent cells during chimeric antigen receptor T cell (CAR-T) CD19 immunotherapy.
2023/49/N/NZ6/02818
Keywords:
Acute Lymphoblastic Leukemia Mass Cytometry (CyTOF – Cytometry by time of flight) lymphocyte subpopulation Immunological checkpoints CAR-T (Chimeric Antigen Receptor T cell therapy) CD19 cellular immunotherapy
Descriptors:
- NZ6_02:
- NZ5_07:
- NZ3_01:
Panel:
NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology
Host institution :
Uniwersytet Medyczny w Łodzi, Wydział Lekarski
woj. łódzkie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 22 - announced on 2023-03-16
Amount awarded: 209 680 PLN
Project start date (Y-m-d): 2024-01-08
Project end date (Y-m-d): 2027-01-07
Project duration:: 36 months (the same as in the proposal)
Project status: Pending project
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- Articles in post-conference publications (1)
- CD19-CAR T-cell therapy with sorafenib in post-HSCT relapse of mixed phenotype acute leukaemia (MPAL) with phenotypic myeloid to lymphoid lineage switch—A case report and review of the literatureAuthors:A. Oszer, J. Kołodrubiec, B. Pawlik, P. Marschollek, N. Ćwilichowska, J. Jakubowska, K. Bukowska-Strakova, M. Surman, J. Trelińska, K. Miarka-Walczyk, N. Haze, K. Liszka, M. Mielcarek-Siedziuk, K. Kałwak, M. Poręba, A. Pastorczak, S. Janczar, W. MłynarskiAcademic press:British Journal of Hematology (rok: 2024, tom: Sep;205(3), strony: 1215-1219), Wydawca: © 2024 British Society for Haematology and John Wiley & Sons LtdStatus:PublishedDOI:10.1111/bjh.19608 - link to the publication
- Immunophenotypic CAR-T Cells Heterogeneity of Pre- and Post-Infusion of Tisagenlecleucel in Pediatric Patients with BCP-ALL.Authors:Aleksandra Oszer, Bartłomiej Pawlik, Jeremy Chase Crawford, Chris Nevitt, Paweł Marschollek, Natalia Ćwilichowska, Maciej Mazurek, Krzysztof Kalwak, Szymon Janczar, Paul Thomas, Marcin Poręba, Paulina Paulina Velasquez, Wojciech MlynarskiConference:Abstracts from the 2024 Tandem Meetings of ASTCT and CIBMTR, February 21-24, 2024, San Antonio, Texas, USA (rok: 2024, tom: The 2024 Tandem Meetings I Transplantation & Cellular Therapy Meetings of ASTCT and CIBMTR, strony: 30 2S (2024) S174-S229), Wydawca: Elsevier Inc.Data:konferencja 21-24 luty 2024Status:PublishedDOI:10.1016/j.jtct.2023.12.266 - link to the publication