Projects funded by the NCN


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189 projects found matching your search criteria :

  1. Assessment of the functions of granzyme A in neutrophils using induced pluripotent stem cells

    Call: OPUS 20 , Panel: NZ1

    Principal investigator: dr hab. Paulina Maria Kasperkiewicz-Wasilewska

    Politechnika Wrocławska

  2. The role of extracellular proteases – yapsins – in gaining pathogenic advantage by Candida glabrata in the host organism...

    Call: SONATA 16 , Panel: NZ6

    Principal investigator: dr Dorota Anna Satała

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  3. Dissecting cancer activome to develop new generation of antibody-drug conjugates

    Call: OPUS 20 (LAP) , Panel: NZ5

    Principal investigator: dr hab. Marcin Łukasz Poręba

    Politechnika Wrocławska

  4. Study on genetic, epigenetic, transcriptomic and proteomic mechanisms modulating sheep resistance to small ruminant lent...

    Call: OPUS 20 (LAP) , Panel: NZ9

    Principal investigator: dr hab. Ewa Joanna Grochowska

    Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

  5. Omentin as a novel regulator of porcine uterus functioning during the periimplantation period

    Call: SONATA 16 , Panel: NZ9

    Principal investigator: dr Marta Kieżun

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

  6. Irisin as a novel regulator of porcine reproduction: expression and role in the hypothalamic-pituitary-ovarian axis duri...

    Call: OPUS 20 , Panel: NZ9

    Principal investigator: prof. Nina Magdalena Smolińska

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

  7. Cooperation between the extracytoplasmic protein quality control system and the Sec translocon in the process of protein...

    Call: OPUS 20 , Panel: NZ2

    Principal investigator: prof. Joanna Skórko-Glonek

    Uniwersytet Gdański, Wydział Biologii

  8. Defining the interplay between SLPI and the IL-1 family cytokines in the immune response

    Call: SONATA 16 , Panel: NZ6

    Principal investigator: dr Ewa Małgorzata Oleszycka

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  9. Neutrophils heterogeneity based on serine proteases

    Call: SONATA BIS 10 , Panel: NZ3

    Principal investigator: dr Paulina Maria Kasperkiewicz-Wasilewska

    Politechnika Wrocławska

  10. Role of cereal leaf beetle – associated bacteria in the adaptation of their insect host to the insecticides and protease...

    Call: PRELUDIUM 19 , Panel: NZ9

    Principal investigator: Beata Wielkopolan

    Instytut Ochrony Roślin - Państwowy Instytut Badawczy

  11. Molecular mechanism underlying the anti-inflammatory action of CB2 receptor agonists in microglia: participation of the ...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: dr Natalia Eleonora Małek-Chudzik

    Politechnika Wrocławska

  12. Exploring the allosteric regulation of the SARS CoV-2 hydrolases using methyl-TROSY NMR spectroscopy - in search of nove...

    Call: OPUS 19 , Panel: ST4

    Principal investigator: prof. Wiktor Adam Koźmiński

    Uniwersytet Warszawski, Wydział Chemii

  13. Metabolomic and proteomic studies combined with modern magnetic resonance imaging techniques to explore mechanisms of br...

    Call: OPUS 19 , Panel: NZ5

    Principal investigator: prof. Przemko Jacek Kwinta

    Uniwersytet Jagielloński, Collegium Medicum

  14. OMENTIN1 as a new regulator of female reproduction - expression and role in the pituitary - ovary axis. Study on swine m...

    Call: OPUS 19 , Panel: NZ9

    Principal investigator: dr hab. Agnieszka Małgorzata Rak

    Uniwersytet Jagielloński, Wydział Biologii

  15. Participation of cellular proteins in the inhibition of antigen presentation dependent on UL49.5 protein of bovine herpe...

    Call: ETIUDA 8 , Panel: NZ3

    Principal investigator: Magda Dominika Wąchalska

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  16. Tannerella forsythia: regulation of intra- and extracellular proteolytic activity in pathogenicity mechanism.

    Call: PRELUDIUM 2 , Panel: NZ1

    Principal investigator: Mirosław Książek

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  17. Proteomic insights into the mechanism of the acrosome reaction in sturgeon (Acipenser baerii) spermatozoa

    Call: OPUS 18 , Panel: NZ9

    Principal investigator: dr hab. Mariola Aleksandra Dietrich

    Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk

  18. Host sex effect on immunity and protection after oral immunization with Fasciola hepatica cysteine protease and the para...

    Call: OPUS 18 , Panel: NZ6

    Principal investigator: dr hab. Małgorzata Joanna Kęsik-Brodacka

    Narodowy Instytut Leków

  19. Novel analogs of human cathelicidin (LL-37) with enhanced resistant to enzymatic degradation. Design chemical synthesis ...

    Call: PRELUDIUM BIS 1 , Panel: ST4

    Principal investigator: prof. Adam Jerzy Lesner

    Uniwersytet Gdański, Wydział Chemii

  20. Molecular mechanisms modulating the function of UCH-L1 deubiquitinase in human mitochondria

    Call: OPUS 18 , Panel: NZ3

    Principal investigator: prof. Agnieszka Małgorzata Chacińska

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  21. The KLIKK proteases of human pathogen Tannerella forsythia: putative virulence factors with unique biochemical and struc...

    Call: OPUS 18 , Panel: NZ1

    Principal investigator: dr Mirosław Książek

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  22. SufA bacterial protease inhibitors as potential diagnostic tools and antibacterial agents.

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Ewa Magdalena Burchacka

    Politechnika Wrocławska

  23. Hijacking the ubiquitin-proteasome system by the UL49.5 protein of bovine herpesvirus 1 as an immune evasion strategy – ...

    Call: PRELUDIUM 18 , Panel: NZ6

    Principal investigator: dr Magda Dominika Wąchalska

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  24. Inhibitors of serine proteases as regulators of dendritic cell function.

    Call: MAESTRO 1 , Panel: NZ5

    Principal investigator: prof. Joanna Cichy

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  25. Design and synthesis of proteolytically stable and cell permeable activators of human 20S proteasome and assessing their...

    Call: PRELUDIUM BIS 1 , Panel: NZ7

    Principal investigator: dr hab. Elżbieta - Jankowska

    Uniwersytet Gdański, Wydział Chemii

  26. Effect of vitamin D3 supplementatioin of pigs diet on transcriptome and proteome in selected tissues.

    Call: PRELUDIUM BIS 1 , Panel: NZ9

    Principal investigator: dr hab. Maria Paulina Oczkowicz

    Instytut Zootechniki - Państwowy Instytut Badawczy

  27. Cellular adaptation to cold.

    Call: GRIEG 1 , Panel: NZ3

    Principal investigator: dr Wojciech Mieczysław Pokrzywa

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

  28. Preventing the accumulation of cytotoxic oligomers, that are causative agents of neurodegenerative diseases and Type 2 D...

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: dr hab. Elżbieta - Jankowska

    Uniwersytet Gdański, Wydział Chemii

  29. Effects of proteasome inhibition on mitochondrial homeostasis.

    Call: OPUS 17 , Panel: NZ5

    Principal investigator: prof. Agnieszka Małgorzata Chacińska

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  30. Analysis of SWI/SNF complexes in Arabidopsis and of their activity's regulation through 26S proteasome with special cons...

    Call: PRELUDIUM 1 , Panel: NZ1

    Principal investigator: Anna Teodora Rolicka

    Uniwersytet Warszawski, Wydział Biologii

  31. Epigenetic regulation of pro-epileptic protease Matrix Metalloproteinase-9 expression in the hippocampus during epilepto...

    Call: OPUS 1 , Panel: NZ2

    Principal investigator: dr hab. Marcin Bartłomiej Rylski

    Centrum Medyczne Kształcenia Podyplomowego

  32. Doubly knotted proteins - frontiers of topological complexity of proteins

    Call: OPUS 16 , Panel: NZ1

    Principal investigator: dr hab. Joanna Ida Sułkowska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  33. Anisakis simplex as a parasite of public health importance: transcriptome and proteome as a source of information on the...

    Call: OPUS 16 , Panel: NZ9

    Principal investigator: prof. Iwona Urszula Bogacka

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

  34. Molecular basics of type II transmembrane serine proteases (TTSPs)-mediated activation of influenza viruses

    Call: BEETHOVEN LIFE 1 , Panel: NZ1

    Principal investigator: dr Paweł Zmora

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  35. Multi-level molecular assessment based on laser microdissection of corneas to reveal biomarkers and therapeutic targets ...

    Call: OPUS 16 , Panel: NZ5

    Principal investigator: prof. Marzena Magdalena Gajęcka

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  36. Characterization of two novel proteases from the human periodontopathogen Tannerella forsythia

    Call: PRELUDIUM 16 , Panel: NZ1

    Principal investigator: Irena Maria Waligórska

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  37. Dissecting the proteolytic fingerprint of breast cancer tissues using mass cytometry for personalized oncology.

    Call: SONATA 14 , Panel: NZ5

    Principal investigator: dr Marcin Łukasz Poręba

    Politechnika Wrocławska, Wydział Chemiczny

  38. Application of lanthanides in activity-based probes for the simultaneous detection of proteolytic enzymes.

    Call: HARMONIA 10 , Panel: ST5

    Principal investigator: prof. Marcin Drąg

    Politechnika Wrocławska, Wydział Chemiczny

  39. CP protease of the O'nyong-nyong virus: substrate profiling, design and synthesis of inhibitors and activity-based probe...

    Call: OPUS 15 , Panel: NZ6

    Principal investigator: dr hab. Marcin Sieńczyk

    Politechnika Wrocławska

  40. Integrated transcriptomic, proteomic and metabolomic analysis of molecules that mediate homing of mesenchymal stem cells...

    Call: OPUS 15 , Panel: NZ5

    Principal investigator: prof. Agnieszka Piekiełko-Witkowska

    Centrum Medyczne Kształcenia Podyplomowego

  41. Association of TXNDC5 and calreticulin with decreased ER stress, allowing resistant multiple myeloma cells to by-pass pr...

    Call: PRELUDIUM 15 , Panel: NZ5

    Principal investigator: Tadeusz Franciszek Kubicki

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski

  42. Chemerin - a new regulator of the porcine corpus luteum during the oestrous cycle

    Call: PRELUDIUM 14 , Panel: NZ9

    Principal investigator: Edyta Rytelewska

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

  43. Features of human serum proteome involved in response to ionizing radiation

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: prof. Piotr Michał Widłak

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie Oddział w Gliwicach

  44. Toward understanding allosteric regulation of the proteasome activity

    Call: OPUS 1 , Panel: ST5

    Principal investigator: dr hab. Elżbieta Jankowska

    Uniwersytet Gdański, Wydział Chemii

  45. The effect of peroxisome proliferator-activated receptor gamma (PPARy) ligands on the transrciptome and proteome profile...

    Call: PRELUDIUM 14 , Panel: NZ9

    Principal investigator: Zuzanna Kunicka

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

  46. Functional and structural interplay between two mitochondrial inner membrane proteases, AtFTSH4 and AtOMA1, in Arabidops...

    Call: OPUS 14 , Panel: NZ2

    Principal investigator: prof. Hanna Elżbieta Jańska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  47. Cellular proteases during coronaviral infection

    Call: OPUS 14 , Panel: NZ6

    Principal investigator: dr hab. Krzysztof Pyrć

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  48. Novel inhibitors of herpes virus protease

    Call: PRELUDIUM 14 , Panel: NZ6

    Principal investigator: Magdalena Anna Pachota

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  49. Role of proteasome in the regulation of Gli protein activity by the Hedgehog pathway

    Call: OPUS 14 , Panel: NZ3

    Principal investigator: dr hab. Paweł Niewiadomski

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  50. Biodegradation of nitrofuranes derivatives by environmental bacteria - from metabolic pathways to proteome and genome mo...

    Call: OPUS 14 , Panel: NZ9

    Principal investigator: prof. Ewa Kaczorek

    Politechnika Poznańska, Wydział Technologii Chemicznej