Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Cellular adaptation to cold.

2019/34/H/NZ3/00691

Keywords:

hibernation hypothermia protein synthesis proteostasis RNA metabolism protein degradation the ubiquitin-proteasome system autophagy C. elegans

Descriptors:

  • NZ3_001:
  • NZ3_002:
  • NZ3_014:

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Wojciech Mieczysław Pokrzywa 

Number of co-investigators in the project: 6

Call: GRIEG 1 - announced on 2019-06-17

Amount awarded: 6 389 842 PLN

Project start date (Y-m-d): 2021-01-15

Project end date (Y-m-d): 2024-04-30

Project duration:: 40 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  1. Pheromone-based communication influences the production of somatic extracellular vesicles in C. elegans
    Authors:
    Szczepańska A, Olek K, Kołodziejska K, Yu J, Tudu Ibrahim A, Adamkiewicz L, Schroeder FC, Pokrzywa W*, & Turek M*
    Academic press:
    Nature Communications (rok: 2024, tom: 15, strony: 45676), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41467-024-47016-x - link to the publication
  2. A novel de novo FEM1C variant is linked to neurodevelopmental disorder with absent speech, pyramidal signs, and limb ataxia.
    Authors:
    Abhishek Anil Dubey, Magdalena Krygier, Natalia A Szulc, Karolina Rutkowska, Joanna Kosińska, Agnieszka Pollak, Małgorzata Rydzanicz, Tomasz Kmieć, Maria Mazurkiewicz-Bełdzińska, Wojciech Pokrzywa, Rafał Płoski
    Academic press:
    Human Molecular Genetics (rok: 2022, tom: 32 (7), strony: 1152–1161), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.18150/9TQUTI - link to the publication
  3. Ferritin-mediated iron detoxification promotes hypothermia survival in Caenorhabditis elegans and murine neurons.
    Authors:
    Tina Pekec, Jarosław Lewandowski, Alicja A. Komur, Daria Sobańska, Yanwu Guo, Karolina Świtońska-Kurkowska, Jędrzej M. Małecki, Abhishek Anil Dubey, Wojciech Pokrzywa, Marcin Frankowski, Maciej Figiel, and Rafal Ciosk
    Academic press:
    Nature Communications (rok: 2022, tom: 13, strony: 45676), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41467-022-32500-z - link to the publication
  4. Muscle-derived exophers promote reproductive fitness
    Authors:
    Michał Turek, Katarzyna Banasiak, Małgorzata Piechota, Niech Shanmugam, Matylda Macias, Małgorzata Alicja Śliwińska, Marta Niklewicz, Konrad Kowalski, Natalia Nowak, Agnieszka Chacinska, Wojciech Pokrzywa
    Academic press:
    EMBO (rok: 2021, tom: 22, strony: 45670), Wydawca: EMBO press
    Status:
    Published
    DOI:
    10.15252/embr.202052071 - link to the publication
  5. Muscle-derived exophers promote reproductive fitness
    Authors:
    Michał Turek, Katarzyna Banasiak, Małgorzata Piechota, Niech Shanmugam, Matylda Macias, Małgorzata Alicja Śliwińska, Marta Niklewicz, Konrad Kowalski, Natalia Nowak, Agnieszka Chacinska, Wojciech Pokrzywa
    Academic press:
    EMBO (rok: 2021, tom: 22, strony: 45670), Wydawca: EMBO press
    Status:
    Published
    DOI:
    10.15252/embr.202052071 - link to the publication

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