Characterization of two novel proteases from the human periodontopathogen Tannerella forsythia

2018/31/N/NZ1/02891

Keywords

Descriptors

  • NZ1_2: Biochemia
  • NZ1_1: Biologia molekularna
  • NZ1_10: Biologia drobnoustrojów

Panel

NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Irena Maria Waligórska

Number of co-investigators in the project: 2

Call

PRELUDIUM 16 – announced on 2018-09-14

Amount awarded
139 485 PLN
Project start date
2019-08-07
Project end date
2022-08-06
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (2)

  1. Latency, thermal stability, and identification of an inhibitory compound of mirolysin, a secretory protease of the human periodontopathogen Tannerella forsythia

    Authors:
    Zak KM, Bostock MJ, Waligorska I, Thøgersen IB, Enghild JJ, Popowicz GM, Grudnik P, Potempa J, Ksiazek M.
    Academic press:
    Journal of enzyme inhibition and medicinal chemistry (year: 2021, volume: 36, pages: 1267–1281), Publisher: Taylor & Francis Group
    Status:
    Published
    DOI:
    10.1080/14756366.2021.1937619 – link to the publication
  2. Periodontopathogens interfere with the human renin-angiotensin system through a surface-attached protease

    Authors:
    Irena Waligorska, Krzysztof Zak, Joanna Budziaszek, Ewa Bielecka, Tomasz Kantyka, Joanna Koziel, Ida Thogersen, Jan Enghild, Przemyslaw Grudnik, Jan Potempa, Miroslaw Ksiazek
    Academic press:
    bioRxiv (year: 2024, volume: brak, pages: 46045), Publisher: Cold Spring Harbor Laboratory
    Status:
    Published
    DOI:
    10.1101/2024.06.20.599981 – link to the publication

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