Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Features of human serum proteome involved in response to ionizing radiation

2011/01/B/NZ4/03563

Keywords:

biomarkers cancer mass spectrometry proteomics radiation serum

Descriptors:

  • NZ2_3: Proteomics
  • NZ4_11: Metabolism
  • NZ7_2: Environment and health risks

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie Oddział w Gliwicach

woj. śląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Piotr Widłak 

Number of co-investigators in the project: 9

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 675 000 PLN

Project start date (Y-m-d): 2011-12-21

Project end date (Y-m-d): 2014-12-20

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. zestaw komputerowy (planowany w pakiecie z oprogramowaniem) (7 292 PLN)
  2. Zamrażarka niskotemperaturowa (60 000 PLN)
  3. Oprogramowanie do analiz proteomicznych (10 000 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  1. Radiotherapy-induced changes in serum lipid profile of patients with prostate or head and neck cancer
    Authors:
    Ros M, Jelonek K, Pietrowska M, Zagdanski A, Suchwalko A, Jastrzab T, Polanska J, Chawinska E, Dominczyk I, Rutkowski T, Miszczyk T, Widlak P
    Academic press:
    Jacobs Journal of Radiation Oncology , Wydawca: Jacobs Publishers
    Status:
    Submitted
    DOI:
    brak - link to the publication
  2. Partial-body irradiation in patients with prostate cancer treated with IMRT has little effect on the composition of serum proteome
    Authors:
    107. Pietrowska M, Jelonek K, Polanska J, Wojakowska A, Marczak L, Chawinska E, Chmura A, Majewski W, Miszczyk L, Widlak P
    Academic press:
    Proteomes (rok: 2015, tom: 3, strony: 117-131), Wydawca: MDPI - Open Access Publishing
    Status:
    Published
    DOI:
    10.3390/proteomes3030117 - link to the publication
  3. Radiation-induced changes in serum lipidome of head and neck cancer patients
    Authors:
    Jelonek K, Pietrowska M, Ros M, Zagdanski A, Suchwalko A, Polanska J, Marczyk M, Rutkowski T, Skladowski K, Clench MR, Widlak P
    Academic press:
    International Journal of Molecular Sciences (rok: 2014, tom: 15, strony: 6609-6624), Wydawca: MDPI - Open Access Publishing
    Status:
    Published
    DOI:
    10.3390/ijms15046609 - link to the publication
  4. Serum proteome signature of radiation response: upregulation of inflammation-related factors, and downregulation of apolipoproteins and coagulation factors in cancer patients subjected to radiotherapy – a pilot study
    Authors:
    Widlak P, Jelonek K, Wojakowska A, Pietrowska M, Polanska J, Marczak L, Miszczyk L, Skladowski K
    Academic press:
    International Journal of Radiation Oncology Biology and Physics (rok: 2015, tom: 92, strony: 1108-1115), Wydawca: Elsevier Inc.
    Status:
    Published
    DOI:
    10.1016/j.ijrobp.2015.03.040 - link to the publication
  5. MALDI-MS-Based Profiling of Serum Proteome: Detection of Changes Related to Progression of Cancer and Response to Anticancer Treatment
    Authors:
    Pietrowska M, Widłak P
    Academic press:
    International Journal of Proteomics (rok: 2012, tom: 2012, strony: 926427), Wydawca: Hindawi Publishing Corporation
    Status:
    Published
    DOI:
    10.1155/2012/926427 - link to the publication
  6. Radiotherapy-related changes in serum proteome patterns of head and neck cancer patients; the effect of low and medium doses of radiation delivered to large volumes of normal tissue
    Authors:
    Widlak P, Pietrowska M, Polanska J, Rutkowski T, Jelonek K, Kalinowska-Herok M, Gdowicz-Klosok A, Wygoda A, Tarnawski R, Skladowski K
    Academic press:
    Journal of Translational Medicine (rok: 2013, tom: 11, strony: e299), Wydawca: BioMed Central
    Status:
    Published
    DOI:
    10.1186/1479-5876-11-299 - link to the publication

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