Projects funded by the NCN

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103 projects found matching your search criteria :

  1. Simultaneous stimulation of muscarinic M4 receptor and selected receptors involved in the regulation of glutamate releas...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: dr hab. Joanna Wierońska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  2. The effect of the metabotropic glutamatergic receptor ligands on potentiating the antidepressant-like actvity of scopola...

    Call: PRELUDIUM 10 , Panel: NZ7

    Principal investigator: Karolina Podkowa

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  3. Maternal diet during gestation and nutrition as a risk factor for cocaine use disorder in offspring - preclinical behavi...

    Call: OPUS 11 , Panel: NZ4

    Principal investigator: prof. Małgorzata Filip

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  4. The role of the endogenuous opioid system in prosocial behavior

    Call: OPUS 11 , Panel: NZ4

    Principal investigator: dr hab. Jan Rodriguez Parkitna

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  5. Altered interaction between NMDA receptor subunits and their scaffolding proteins as a critical step to control drug see...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: prof. Małgorzata Filip

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  6. Role of the NLRP3 inflammasome in the mechanisms of action of antidepressant drugs - study in an animal model of depress...

    Call: PRELUDIUM 9 , Panel: NZ7

    Principal investigator: dr Ewa Trojan

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  7. The role of the neuron-microglia CX3CL1-CX3CR1 and CD200-CD200R protein systems in molecular mechanisms of antipsychotic...

    Call: OPUS 10 , Panel: NZ7

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  8. Search for new targets for an effective therapy of neuropathic pain and enhancement of opioids effects basing on the exa...

    Call: OPUS 11 , Panel: NZ4

    Principal investigator: prof. Joanna Mika

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  9. Effects of chosen chemokines on the activity and synaptic transmission in central and basolateral complex of the amygdal...

    Call: PRELUDIUM 11 , Panel: NZ4

    Principal investigator: Joanna Sowa

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  10. Pharmacological properties and neurotoxicity of novel NBOMe derivatives

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: prof. Krystyna Gołembiowska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  11. Impact of early-life stress on maturation, permeability of blood brain-barrier and neuroinflammatory processes activatio...

    Call: PRELUDIUM 12 , Panel: NZ4

    Principal investigator: Anna Solarz

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  12. Impact of pharmacogenetic profiles on depression treatment outcomes

    Call: SONATINA 5 , Panel: NZ2

    Principal investigator: dr Małgorzata Maria Borczyk

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  13. Chronic pain in obesity: from cellular mechanisms to new strategies for targeted therapy.

    Call: SONATA 17 , Panel: NZ5

    Principal investigator: dr Anna Piotrowska-Murzyn

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  14. New strategies in the pharmacotherapy of neuropathic pain based on modulation of the chemokine system and its influence ...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: prof. Joanna Gabriela Mika

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  15. Cognitive impairment in chronic pain - CBD as the undervalued remedy.

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: prof. Katarzyna Maria Starowicz-Bubak

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  16. Plasticity of neuroanatomically identified synaptic inputs and functions of the dorsal raphe nucleus in an animal model ...

    Call: OPUS 25 , Panel: NZ4

    Principal investigator: prof. Krzysztof Tokarski

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  17. The effect of prolonged treatment with the new antipsychotics brexpiprazole and lumateperone on human liver function usi...

    Call: OPUS 26 , Panel: NZ4

    Principal investigator: dr Przemysław Danek

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  18. Modeling Progression of α-Synucleinopathy in Noradrenergic and Serotonergic Systems – Possible Link with Prodromal Sympt...

    Call: PRELUDIUM 23 , Panel: NZ4

    Principal investigator: Anna Alwani

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  19. Zinc Deficiency: An essential Variable for the Induction od Resistance to Antidepressants

    Call: PRELUDIUM 13 , Panel: NZ5

    Principal investigator: dr Anna Rafało-Ulińska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  20. Development of unique molecular probes: low-basicity agonists for the study of 5-HT7 receptor function

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Andrzej Bojarski

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  21. How microglia-astrocyte interaction affects neuronal functioning in the dopaminergic system. Analysis of the protective ...

    Call: OPUS 14 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Kuter-Nowak

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  22. New strategies in neuropathic pain pharmacotherapy based on the modulation of the functions of chemokine receptors CCR2 ...

    Call: PRELUDIUM 15 , Panel: NZ7

    Principal investigator: dr Klaudia Kwiatkowski

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  23. The role of cognitive bias in individual vulnerability to to the transition from controlled use to uncontrolled abuse of...

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: dr hab. Rafał Ryguła

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  24. The effect of chronic treatment with iasenapine and iloperidone on the expression and activity of cytochrome P450 in the...

    Call: PRELUDIUM 16 , Panel: NZ7

    Principal investigator: dr Przemysław Danek

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  25. Searching for effective strategies to protect neuronal cells against hypoxia and ischemia: Identification of neuroprotec...

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Małgorzata Kajta

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  26. The influence of muscarinic acetylcholine receptors (M1, M4 and M5) and serotonergic 5-HT1A receptor modulation on cogni...

    Call: PRELUDIUM 16 , Panel: NZ7

    Principal investigator: dr Paulina Cieślik

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  27. Wpływ wybranych chemokin na właściwości komórek nerwowych i przekaźnictwo synaptyczne w obszarze kompleksu ciała migdało...

    Call: ETIUDA 7 , Panel: NZ4

    Principal investigator: Joanna Sowa

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  28. Pharmacological modulation of histamine H3 and H4 receptors - a new perspective in the treatment of neuropathic pain

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Katarzyna Popiołek-Barczyk

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  29. Endocannabinoid regulation of the motivational tone at the mesolimbic system driven by inflammation

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: prof. Katarzyna Maria Starowicz-Bubak

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  30. In vivo effects, underlying signaling pathways and mechanism of action of ghrelin receptor agonist against pathological ...

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Piotr Chmielarz

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  31. Investigation of molecular mechanisms of rapid antidepressant action of NLX-101, a biased agonist of the 5-HT1A receptor...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  32. Molecular profiling of novel antipsychotic drug candidates

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: dr hab. Jan Manuel Rodriguez Parkitna

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  33. A premotor disease signature for ALS

    Call: JPco-fuND2 Call 2021 , Panel: NZ7

    Principal investigator: dr Wojciech Kuban

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  34. Maternal obesity as a risk factor of autism spectrum disorder in offspring - in search of the role of the gut microbiota...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr Dawid Mateusz Gawliński

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  35. New approach to the treatment of Alzheimer's disease targetingresolution of inflammation and modulation of biomechanical...

    Call: OPUS 22 , Panel: NZ4

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  36. Enhancement of antidepressant therapy by combined administration of hyperforin and ketamine: behavioral and molecular st...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Bartłomiej Pochwat

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  37. Investigation of the effects and mechanisms of action of Deep Brain Stimulation in two animal models of treatment-resist...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  38. The role of selected signaling pathways in zinc deficiency

    Call: OPUS 10 , Panel: NZ4

    Principal investigator: prof. Gabriel Nowak

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  39. The evaluation of therapeutic potential of β-caryophyllene in animal schizophrenia model - behavioral and molecular stud...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Magdalena Białoń

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  40. Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer's disease

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Karolina Barbara Przepiórska-Drońska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  41. Brain cytochrome P450 as a new target for the treatment of neurological and psychiatric diseases. Studies with human neu...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: prof. Władysława Anna Daniel

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  42. The cross-talk between 5-HTR2A and mGluR2 as a window for antidepressant effects of psilocybin.

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: prof. Andrzej Pilc

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  43. Semaglutide and neurodevelopment: investigating risks arising from prenatal exposure to a widely popular drug for diabet...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr Agnieszka Wnuk

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  44. Potential pharmacological strategies aimed at alleviating cognitive dysfunctions accompanying oncological therapy while ...

    Call: OPUS 26 , Panel: NZ5

    Principal investigator: dr hab. Joanna Wierońska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  45. Mechanisms of Antidepressant Action of Psilocybin: The Role of 5-HT2B-5-HT1A Receptor Dimerization and GSK-3β Activation...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: dr hab. Agata Faron-Górecka

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  46. Modulation of amygdala neural network activity by the 5-HT7 receptor

    Call: OPUS 11 , Panel: NZ4

    Principal investigator: prof. Krzysztof Tokarski

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  47. The role of halogen bonding in interaction of ligands with SERT.

    Call: SONATA 11 , Panel: NZ7

    Principal investigator: dr Jakub Staroń

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  48. Molecular characteristics of stress-resilient phenotype using mice models.

    Call: OPUS 12 , Panel: NZ4

    Principal investigator: prof. Marta Dziedzicka-Wasylewska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  49. Evaluation of interactions of aripiprazole, the atypical amtipsychotic drug, with the selected antidepressants in the ra...

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: dr hab. Zofia Rogóż

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  50. Evaluation of the influence of progressive noradrenergic neurodegeneration on dopaminergic system functioning in context...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: dr Grzegorz Kreiner

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

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