Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Molecular characteristics of stress-resilient phenotype using mice models.

2016/23/B/NZ4/01086

Keywords:

stress-resilience depression micro-RNA molecular markers NET-KO mice C57Bl/6J mice SWR/J mice,

Descriptors:

  • NZ4_12: Other related subjects

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Marta Dziedzicka-Wasylewska 

Number of co-investigators in the project: 7

Call: OPUS 12 - announced on 2016-09-15

Amount awarded: 1 542 039 PLN

Project start date (Y-m-d): 2017-08-04

Project end date (Y-m-d): 2022-08-03

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Stereotaksja dla myszy (35 000 PLN)
  2. Termocykler gradientowy.
  3. Robot stereotaktyczny z systemem do iniekcji i wiertarką (103 000 PLN)
  4. Urządzenie do anestezji zwierząt laboratoryjnych.
  5. waga precyzyjna.

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (5)
  1. Serum Level of miR-1 and miR-155 as Potential Biomarkers of Stress-Resilience of NET-KO and SWR/J Mice
    Authors:
    Joanna Solich, Maciej Kuśmider, Agata Faron-Górecka, Paulina Pabian, Magdalena Kolasa, Beata Zemła, Marta Dziedzicka-Wasylewska
    Academic press:
    Cells (rok: 2020, tom: 9 (4), strony: 917), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells9040917 - link to the publication
  2. What Do the Animal Studies of Stress Resilience Teach Us?
    Authors:
    Marta Dziedzicka-Wasylewska, Joanna Solich , Agata Korlatowicz, Agata Faron-Górecka
    Academic press:
    Cells (rok: 2021, tom: 10, strony: 1630), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells10071630 - link to the publication
  3. MicroRNA Let-7e in the Mouse Prefrontal Cortex Differentiates Restraint-Stress-Resilient Genotypes from Susceptible Genotype
    Authors:
    Joanna Solich, Magdalena Kolasa, Agata Faron-Górecka , Jacek Hajto, Marcin Piechota, Marta Dziedzicka-Wasylewska
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 9439), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22179439 - link to the publication
  4. Restraint Stress in Mice Alters Set of 25 miRNAs Which Regulate Stress- and Depression-Related mRNAs
    Authors:
    Joanna Solich, Maciej Kuśmider, Agata Faron-Górecka, Paulina Pabian, Marta Dziedzicka-Wasylewska
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 21(24), strony: 9469), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21249469 - link to the publication
  1. Alterations in miR-1 regulated mRNAs in the strains of mice differently sensitive to acute restraint stress.
    Authors:
    Kuśmider Maciej, Solich Joanna, Faron-Górecka Agata, Pabian Paulina, Kolasa Magdalena, Dziedzicka-Wasylewska Marta
    Conference:
    FENS 2020 Virtual Forum (rok: 2020, ), Wydawca: FENS
    Data:
    konferencja 11-15 lipiec 2020
    Status:
    Published
  2. The microRNA as biomarker of stress-resilience – animal studies
    Authors:
    Solich J., Kuśmider M., Kolasa M., Faron-Górecka A., Pabian P., Szlachta M., Dziedzicka-Wasylewska M.
    Conference:
    32nd ECNP Congress (rok: 2019, ), Wydawca: ECNP
    Data:
    konferencja 43745
    Status:
    Published
  3. Reactivity of mice lacking the functional norepinephrine transporter (NET-KO mice) to restraint stress - the delayed effects.
    Authors:
    Solich J., Pabian P., Kolasa M., Faron-Górecka A., Kuśmider M., Szlachta M., Dziedzicka-Wasylewska M.
    Conference:
    11th FENS Forum of Neuroscience (rok: 2018, ), Wydawca: FENS
    Data:
    konferencja 7-11.07.2018
    Status:
    Published
  4. The miRNAs as biomarker of stress-resilience or susceptibility – the mouse study.
    Authors:
    Solich Joanna, Kuśmider Maciej, Pabian Paulina, Faron-Górecka Agata, Kolasa Magdalena, Dziedzicka-Wasylewska Marta
    Conference:
    FENS 2020 Virtual Forum (rok: 2020, ), Wydawca: FENS
    Data:
    konferencja 11-15 lipiec 2020
    Status:
    Published
  5. NET-KO mice as a stress-resistant model-miRNAs studies
    Authors:
    Solich J., Kusmider M., Kolasa M., Faron-Gorecka A., Pabian P., Szlachta M., Dziedzicka-Wasylewska M.
    Conference:
    Cognitive affective biases - from mechanisms to disease symptoms (rok: 2019, ), Wydawca: PHARMACOLOGICAL REPORTS
    Data:
    konferencja 43598
    Status:
    Published

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