Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Brain cytochrome P450 as a new target for the treatment of neurological and psychiatric diseases. Studies with human neuronal cells and transgenic animals.

2022/45/B/NZ7/02419

Keywords:

brain cytochrome P450 dopamine serotonin neuronal cells transgenic animals neurological and psychiatric diseases CRISPR-Cas9 letivirus vector AAV vector HPLC,

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ4_9: Systems neurobiology
  • NZ3_6: Cell neurobiology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Władysława Anna Daniel 

Number of co-investigators in the project: 6

Call: OPUS 23 - announced on 2022-03-28

Amount awarded: 2 178 906 PLN

Project start date (Y-m-d): 2023-02-03

Project end date (Y-m-d): 2027-02-02

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  1. The Engagement of Cytochrome P450 Enzymes in Tryptophan Metabolism
    Authors:
    Anna Haduch, Ewa Bromek, Wojciech Kuban, Władysława Anna Daniel (review)
    Academic press:
    Metabolites (rok: 2023, tom: 13, strony: 629), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/metabo13050629 - link to the publication