Projects funded by the NCN

Essential oils, propolis and nanoparticles of silver and copper as an alternative or supporting agent for conventional t...

Call: PRELUDIUM 8 , Panel: NZ7

Principal investigator: Katarzyna Gucwa

Politechnika Gdańska, Wydział Chemiczny

DNA repair pathways contributing to resistance to photodynamic therapy and as possible theraupeutic targets

Call: OPUS 8 , Panel: NZ5

Principal investigator: dr hab. Elżbieta Speina

Instytut Biochemii i Biofizyki PAN

Role of the selected anti-tumor agents transported by electropermeabilization to the drug-sensitive and drug-resistant c...

Call: PRELUDIUM 8 , Panel: NZ7

Principal investigator: dr Joanna Weżgowiec

Politechnika Wrocławska, Wydział Podstawowych Problemów Techniki

The influence of bone marrow microenvironment on the regulation of BRCA1 mRNA translation in leukemia cells; role in the...

Call: SONATA 8 , Panel: NZ3

Principal investigator: dr Paulina Podszywałow-Bartnicka

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Identification of new, clinically relevant genetic and epigenetic aberrations by next-generation sequencing in chronic m...

Call: HARMONIA 6 , Panel: NZ5

Principal investigator: dr Tomasz Stokłosa

Warszawski Uniwersytet Medyczny, Wydział Lekarski

Immunological biomarkers of drug resistant epilepsy and response to immunomodulatory therapy with ACTH in children

Call: PRELUDIUM 6 , Panel: NZ4

Principal investigator: Magdalena Kaczorowska-Frontczak

Instytut "Pomnik - Centrum Zdrowia Dziecka"

New drug carriers in targeted anticancer therapy

Call: OPUS 1 , Panel: ST5

Principal investigator: prof. Artur Terzyk

Uniwersytet Mikołaja Kopernika, Wydział Chemii

Unlocking nature's potential - exploring the ability of newly isolated from the environment bacteriophage and its enzyme...

Call: PRELUDIUM 22 , Panel: NZ9

Principal investigator: Aleksandra Łukasiak

Uniwersytet Gdański, Wydział Biologii

Unveiling the molecular signature underlying resistance to CD19 CAR-T therapy in malignant cells.

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Marta Krawczyk

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

Targeted poloxamer micelles with selected drugs as a strategy for overcoming the mechanisms of multidrug resistance in p...

Call: PRELUDIUM BIS 4 , Panel: NZ7

Principal investigator: prof. Tomasz Gośliński

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Three-phase drug carriers - design towards a prolonged release, development of a transport model and its verification. C...

Call: PRELUDIUM BIS 4 , Panel: ST8

Principal investigator: prof. Anna Trusek

Politechnika Wrocławska

The use of genetic analysis of liquid biopsy for predicting and monitoring ofresponse to therapies and tumor evolution i...

Call: OPUS 22 , Panel: NZ7

Principal investigator: dr Magdalena Olbryt

Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy Instytut Badawczy, Oddział w Gliwicach

Inhibiting the Mitochondrial Intermembrane Space Assembly pathway as a newapproach to prevent metabolic reprogramming of...

Call: OPUS 22 , Panel: NZ5

Principal investigator: dr hab. Carlo Vascotto

Instytut Hematologii i Transfuzjologii

Development of phage-based tool with the potential to treat antibiotic-resistant gonorrhea

Call: PRELUDIUM BIS 3 , Panel: NZ6

Principal investigator: dr hab. Monika Adamczyk-Popławska

Uniwersytet Warszawski, Wydział Biologii

RE-SENSE: Dual-loaded lipid nanoparticles to overcome the resistance of non-small cell lung cancer cells to personalized...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Mikołaj Czajkowski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

In search for molecular targets to overcome doxorubicin resistance in triple-negative breast cancer with the use of inno...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Anna Pogorzelska

Narodowy Instytut Leków

Reversible senescence as a new mechanism of cancer cell resistance for chemotherapy. Analysis of the mechanism of cancer...

Call: SONATINA 5 , Panel: NZ3

Principal investigator: dr Karolina Staniak

Politechnika Warszawska, Wydział Chemiczny

FGF/FGFR-signalling in mediation of resistance to therapy in triple-positive breast cancer: clinical implications of PAM...

Call: OPUS 20 , Panel: NZ4

Principal investigator: dr hab. Hanna Romańska-Knight

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Dual CBR1-AKR1C3 inhibitors as a new approach to improve effectiveness and safety of anthracycline therapy.

Call: PRELUDIUM 19 , Panel: NZ7

Principal investigator: Marek Jamrozik

Uniwersytet Jagielloński, Collegium Medicum

Cell adhesion molecules as regulators of tunneling nanotubes (TNTs) formation and protein transfer in leukemia microenvi...

Call: PRELUDIUM BIS 1 , Panel: NZ3

Principal investigator: dr hab. Katarzyna Piwocka

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

The use of olaparib and ATR / CHK1 kinase inhibitors as a targeted anti-cancer therapy based on synthetic lethality

Call: SONATA BIS 9 , Panel: NZ7

Principal investigator: dr hab. Aneta Rogalska

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

The significance of cancer specific PFK-II (PFKFB3 and PFKFB4) isoenzymes inhibition in overcoming resistance to BRAF in...

Call: PRELUDIUM 16 , Panel: NZ5

Principal investigator: Sonia Trojan

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

The combination of radiotherapy with imiquimod and sunitinib as a new therapeutic strategy overcoming some of the tumor ...

Call: SONATA 14 , Panel: NZ5

Principal investigator: dr Magdalena Jarosz-Biej

Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy Instytut Badawczy, Oddział w Gliwicach

Role of RNA binding proteins in resistance to therapy of leukemia cells in bone marrow niche

Call: HARMONIA 10 , Panel: NZ3

Principal investigator: dr Paulina Podszywałow-Bartnicka

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

Tunneling nanotubes (TNTs) within the leukemia microenvironment; influence of metabolic remodeling and implications for ...

Call: OPUS 15 , Panel: NZ3

Principal investigator: dr hab. Katarzyna Piwocka

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

Regulation of epithelial to mesenchymal transition and therapy resistance to antitumor therapies by MCPIP1

Call: SONATA BIS 7 , Panel: NZ5

Principal investigator: dr hab. Katarzyna Miękus

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Molecular and pharmacological approaches based on inhibition of glycolysis to overcome de novo- and antiangiogenic thera...

Call: OPUS 13 , Panel: NZ3

Principal investigator: dr hab. Beata Pająk

Wojskowy Instytut Higieny i Epidemiologii im. gen. Karola Kaczkowskiego

Nano-phages - potential agents in an innovative therapy of bacterial infections

Call: OPUS 12 , Panel: NZ6

Principal investigator: dr Piotr Golec

Uniwersytet Gdański, Wydział Biologii

Fabrication of new photosensitive nanocomposites based on graphite oxide and their interaction with microorganisms which...

Call: OPUS 12 , Panel: ST5

Principal investigator: dr Anna Łukowiak

Instytut Niskich Temperatur i Badań Strukturalnych im. Włodzimierza Trzebiatowskiego Polskiej Akademii Nauk

Identification and targeting molecular drug resistance mechanisms in adult B-cell acute lymphoblastic leukemia

Call: OPUS 1 , Panel: NZ4

Principal investigator: dr hab. Przemysław Juszczyński

Instytut Hematologii i Transfuzjologii

Role of Prolactin-Induced Protein (PIP) in breast cancer progression using an adjuvant therapy.

Call: OPUS 12 , Panel: NZ5

Principal investigator: prof. Piotr Dzięgiel

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Lekarski

Nanoencapsulated Photosensitizing Drugs for Photodynamic Therapy of Resistant Cancers and Microbes

Call: SONATA BIS 6 , Panel: NZ7

Principal investigator: dr Janusz Dąbrowski

Uniwersytet Jagielloński, Wydział Chemii

Old drugs - new perspectives: modulation of antibiotics activity by caffeine and pentoxifylline

Call: SONATA 11 , Panel: NZ7

Principal investigator: dr Anna Woziwodzka

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Characterization and improvement of anti-cancer properties of second generation antagonists of Mdm2 oncoprotein

Call: SONATA 11 , Panel: NZ7

Principal investigator: dr Łukasz Skalniak

Uniwersytet Jagielloński, Wydział Chemii

Phosphorylation of translation initiation factor eIF2alpha as regulator of synthesis of proinflammatory and signaling cy...

Call: PRELUDIUM 10 , Panel: NZ3

Principal investigator: Wioleta Dudka-Ruszkowska

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

Immunomodulatory properties of nanosystems containing membrane-active compounds and their potential in therapy of drug r...

Call: PRELUDIUM 10 , Panel: NZ6

Principal investigator: Ewelina Piktel

Uniwersytet Medyczny w Białymstoku, Wydział Lekarski z Oddziałem Stomatologii i Oddziałem Nauczania w Języku Angielskim

Protein and gene expression analysis in the course of renal cancer stem-like cells' primary resistance to sorafenib in h...

Call: PRELUDIUM 9 , Panel: NZ5

Principal investigator: Zofia Bielecka

Wojskowy Instytut Medyczny