Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Fabrication of new photosensitive nanocomposites based on graphite oxide and their interaction with microorganisms which cause inflammation of apical dental tissues.

2016/23/B/ST5/02480

Keywords:

Graphite oxide metal-phthalocyanines silver nanoparticles photosensitive nanocomposites root canals microflora microbiology bacteria resistance antibacterial agents cytotoxicity photodynamic therapy in endodontics.

Descriptors:

  • ST5_11: Smart materials – self assembled materials, external stimuli-responsive materials
  • NZ7_12: Prevention of human diseases
  • NZ6_4: Bacteriology

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Instytut Niskich Temperatur i Badań Strukturalnych im. Włodzimierza Trzebiatowskiego Polskiej Akademii Nauk

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Anna Łukowiak 

Number of co-investigators in the project: 14

Call: OPUS 12 - announced on 2016-09-15

Amount awarded: 1 124 000 PLN

Project start date (Y-m-d): 2017-08-10

Project end date (Y-m-d): 2021-03-09

Project duration:: 43 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Skaler z podświetlaczem LED (4 790 PLN)
  2. komora laminarna (30 000 PLN)
  3. mikromotor endodontyczny (20 000 PLN)
  4. Mieszadło (925 PLN)
  5. Termocykler.
  6. Wirówka z wyposażeniem.
  7. liofilizator (22 000 PLN)
  8. spektrometr absorpcyjny do szybkich pomiarów (3 019 PLN)
  9. wysokoobrotowa wirówka (14 000 PLN)
  10. mieszadło mechaniczne (1 800 PLN)
  11. Inkubator CO2.
  12. Suszarka laboratoryjna (11 000 PLN)
  13. komora do hodowli bakterii beztlenowych (90 000 PLN)

Information in the final report

  • Publication in academic press/journals (9)
  1. Composite based on graphite oxide, metallic silver and zirconium phthalocyanine coordinated by out-of-plane argininate ligands as photoactive antibacterial additive to endodontic cement
    Authors:
    Y. Gerasymchuk, A. Kędziora, A. Wędzyńska, L. Tahershamsi, V. Chernii, I. Tretyakova, S. Chernii, V. Pekhnyo, I. Korona-Głowniak, A. Malm, Barbara Rajtar, T. Bachanek, D. Piątek, G. Bugla-Płoskońska, A. Lukowiak
    Academic press:
    Journal of Photochemistry and Photobiology A: Chemistry (rok: 2021, tom: 418, strony: 113432), Wydawca: Elsevier B.V.
    Status:
    Published
    DOI:
    10.1016/j.jphotochem.2021.113432 - link to the publication
  2. Consequences Of Long-Term Bacteria's Exposure To Silver Nanoformulations With Different PhysicoChemical Properties
    Authors:
    A. Kędziora, M. Wernecki, K. Korzekwa, M. Speruda, Y. Gerasymchuk, A. Łukowiak, G. Bugla-Płoskońska
    Academic press:
    International Journal of Nanomedicine (rok: 2020, tom: 15, strony: 199—213), Wydawca: Dove Press Ltd
    Status:
    Published
    DOI:
    10.2147/IJN.S208838 - link to the publication
  3. Light-activated zirconium(IV) phthalocyanine derivatives linked to graphite oxide flakes and discussion on their antibacterial activity.
    Authors:
    Lukowiak A, Gerasymchuk Y, Wedzynska A, Tahershamsi L, Tomala R, Strek W, Piatek D, Korona-Glowniak I, Speruda M, Kedziora A, Bugla-Ploskonska G.
    Academic press:
    Applied Science (rok: 2019, tom: 9 (20), strony: 4447), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/app9204447 - link to the publication
  4. Synthesis, Spectroscopic Characterization and Photoactivity of Zr(IV) Phthalocyanines Functionalized with Aminobenzoic Acids and Their GO-Based Composites
    Authors:
    Tahershamsi L., Gerasymchuk Y., Wędzyńska A., Ptak M., Tretyakova I., Łukowiak A.
    Academic press:
    C Journal of Carbon Research (rok: 2019, tom: 6 (1), strony: 1), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/c6010001 - link to the publication
  5. The Impact of Graphite Oxide Nanocomposites on the Antibacterial Activity of Serum
    Authors:
    K. Morka, M. Wernecki, A. Kędziora, M. Książczyk, B. Dudek, Y. Gerasymchuk, A. Lukowiak, J. Bystroń, G. Bugla-Płoskońska
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 7386), Wydawca: MDPI, Basel, Swiss
    Status:
    Published
    DOI:
    10.3390/ijms22147386 - link to the publication
  6. Composites based on graphite oxide and zirconium phthalocyanines with aromatic amino acids as photoactive materials
    Authors:
    Y. Gerasymchuk, A. Wedzynska, L. Tahershamsi, R. Tomala, V. Chernii, I. Tretyakova, A. Lukowiak
    Academic press:
    Chemical Papers (rok: 2021, tom: 75, strony: brak), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s11696-021-01731-7 - link to the publication
  7. Modification of insulin amyloid aggregation by Zr phthalocyanines functionalized with dehydroacetic acid derivatives
    Authors:
    S. Chernii, Y. Gerasymchuk, M. Losytskyy, D. Szymański, I. Tretyakova, A. Łukowiak, V. Pekhnyo, S. Yarmoluk, V. Chernii, V. Kovalska
    Academic press:
    Plos One (rok: 2021, tom: 16(1), strony: e0243904), Wydawca: Public Library of Science (PLOS) USA
    Status:
    Published
    DOI:
    10.1371/journal.pone.0243904 - link to the publication
  8. Patterns of Oral Microbiota in Patients with Apical Periodontitis
    Authors:
    I. Korona-Glowniak, D. Piatek, E. Fornal, A. Lukowiak, Y. Gerasymchuk, A. Kedziora, G. Bugla-Płoskonska, E Grywalska, T Bachanek, A Malm
    Academic press:
    Journal of Clinical Medicine (rok: 2021, tom: 10, strony: 2707), Wydawca: MDPI Basel
    Status:
    Published
    DOI:
    10.3390/jcm10122707 - link to the publication
  9. Perspectives of using photodynamic therapy as antimicrobial therapy in endodontics
    Authors:
    Piątek D.; Gerasymchuk Y.; Korona-Głowniak I.; Bachanek T.; Malm A.; Łukowiak A.
    Academic press:
    Reviews in Medical Microbiology (rok: 2021, tom: Ahead of print, strony: 1), Wydawca: Wolters Kluwer USA
    Status:
    Published
    DOI:
    10.1097/MRM.0000000000000278 - link to the publication

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