Search results

51. Estrogen receptor GPER as a modulator of inflammatory and functional gastrointestinal diseases and colorectal cancer

Principal investigator: Damian Jacenik

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Call: PRELUDIUM 9, Panel: NZ5

52. Self-learning systems in the design of compounds modulating GPCR receptors activation.

Principal investigator: dr hab. Dorota Latek

Uniwersytet Warszawski, Wydział Chemii

Call: OPUS 20, Panel: NZ2

53. Search for new "drug-like" molecules designed as adenosine receptors ligands

Principal investigator: prof. Katarzyna Justyna Kieć-Kononowicz

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: HARMONIA 2, Panel: NZ4

54. Structural studies based on low sequence similarity of G protein-coupled receptors activated by hormones and allosteric …

Principal investigator: dr Dorota Latek

Uniwersytet Warszawski, Wydział Chemii

Call: SONATA 4, Panel: NZ1

55. Development of a method for the structure prediction of GPCRs complexes with agonists and antagonists, including the lig…

Principal investigator: dr Michał Koliński

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: SONATA 1, Panel: NZ2

56. Quinoxalino-2,3-diones as potent tools for exploration of ionotropic kainate receptors

Principal investigator: dr hab. Ewa Monika Szymańska

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 20, Panel: NZ7

57. The mechanism of ligand binding and the conformational changes in the beta2-adrenergic receptor molecule

Principal investigator: dr Anita Płazińska

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny z Oddziałem Analityki Medycznej

Call: SONATA 5, Panel: NZ2

58. EBI2 receptor as a new myelin repair therapy in multiple sclerosis.

Principal investigator: dr hab. Aleksandra Rutkowska

Gdański Uniwersytet Medyczny, Wydział Lekarski

Call: SONATA 18, Panel: NZ3

59. Functional analysis of detected genetic variants of the PCSK9 gene of unknown significance by using in vitro models

Principal investigator: Monika Marta Targońska

Gdański Uniwersytet Medyczny

Call: PRELUDIUM 23, Panel: NZ5

60. Assessing protein-ligand complexes with ML/DL models trained on molecular dynamics-based descriptors.

Principal investigator: dr hab. Paweł Aleksander Siedlecki

Instytut Biochemii i Biofizyki PAN

Call: OPUS 20, Panel: ST4

61. SARMs as a modulators of metabolic functions and oxidative stress in adipose and heart tissues in rat obesity model- in …

Principal investigator: dr Natalia Leciejewska

Uniwersytet Przyrodniczy w Poznaniu, Wydział Medycyny Weterynaryjnej i Nauk o Zwierzętach

Call: PRELUDIUM 18, Panel: NZ7

62. Biochemical bases of ectopic calcification of skeletal muscles in animal model of Duchenne muscular dystrophy (mdx mice)

Principal investigator: prof. Krzysztof Olaf Zabłocki

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: OPUS 15, Panel: NZ4

63. The role of (R,S)-Sulforaphane-induced activation of Nrf2 transcription factor in the regulation of depressive-like beha…

Principal investigator: dr Patrycja Anna Pańczyszyn-Trzewik

Uniwersytet Rzeszowski, Kolegium Nauk Medycznych

Call: PRELUDIUM 12, Panel: NZ4

64. First-in-class dual modulators of necroptosis kinases and 5-HT6 receptors as an innovative approach to develop an effect…

Principal investigator: prof. Jadwiga Handzlik

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 26, Panel: NZ7

65. In vitro and in vivo investigations of the radiometals influence on the ability of CCK2R receptors imaging by the radiol…

Principal investigator: dr hab. Renata Radosława Mikołajczak

Narodowe Centrum Badań Jądrowych

Call: OPUS 2, Panel: ST5

66. New 5-HT6 receptor ligands from the group of sulfonamide derivatives of cyclic arylguanidines in the treatment of gliobl…

Principal investigator: dr Przemysław Patryk Zaręba

Politechnika Krakowska im. Tadeusza Kościuszki, Wydział Inżynierii i Technologii Chemicznej

Call: PRELUDIUM 19, Panel: NZ7

67. Fentanyl opioid designer drugs: from molecular modeling to in vitro studies

Principal investigator: prof. Joanna Sadlej

Narodowy Instytut Leków

Call: OPUS 6, Panel: ST4

68. Novel multi-target ligands of aminergic GPCRs as pharmacological tools to study the pathomechanism of schzophrenia

Principal investigator: dr hab. Agnieszka Anna Kaczor

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

Call: OPUS 14, Panel: NZ7

69. HyperAgro: Hypericum- Agrobacterium interaction as a paradigm to understand pathogenesis-related defence in plant recalc…

Principal investigator: dr Franklin Gregory

Instytut Genetyki Roślin PAN

Call: OPUS 13, Panel: NZ9

70. Extension of the CABS-dock method for protein-peptide docking to modelling of membrane proteins

Principal investigator: Maciej Paweł Ciemny

Uniwersytet Warszawski, Wydział Chemii

Call: PRELUDIUM 15, Panel: NZ1

71. Molecular mechanism of interactions between GPCRs and G protein.

Principal investigator: Stefan Mateusz Mordalski

Instytut Farmakologii PAN

Call: PRELUDIUM 10, Panel: NZ2

72. NMR Spectroscopy as Molecular Language: A Deep Learning Approach to Bioactivity Prediction

Principal investigator: Arkadiusz Bogumił Leniak

Instytut Farmakologii PAN

Call: PRELUDIUM 24, Panel: NZ7

73. Opioid-induced analgesia and hyperalgesia in neuropathic pain - mechanisms and druggable targets

Principal investigator: prof. Barbara Elżbieta Przewłocka

Instytut Farmakologii PAN

Call: OPUS 15, Panel: NZ7

74. Use of comparative oncology approach to dissect the PD-1 intrinsic signalling in osteosarcoma. Can dog be the key for ne…

Principal investigator: Katarzyna Joanna Dziubek

Uniwersytet Gdański, Międzynarodowe Centrum Badań nad Szczepionkami Przeciwnowotworowymi

Call: PRELUDIUM 21, Panel: NZ1

75. A new concept of inhibiting the progression of Alzheimer's disease based on the modification of the blood-brain barrier …

Principal investigator: prof. Agnieszka Basta-Kaim

Instytut Farmakologii PAN

Call: OPUS 28, Panel: NZ4

76. Effects of a novel nonaddictive opioid on response to stress

Principal investigator: dr Łucja Elżbieta Szumiec

Instytut Farmakologii PAN

Call: PRELUDIUM 17, Panel: NZ7

77. The molecular basis of stress-induced anxiety and affective disorders

Principal investigator: dr Michał Korostyński

Instytut Farmakologii PAN

Call: OPUS 2, Panel: NZ2

78. A novel approach based on the optimized multidrug combination for glioblastoma treatment.

Principal investigator: prof. Małgorzata Kucińska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Call: SONATA 16, Panel: NZ7

79. Neurobiological mechanisms of migraine pain - role of opioid and NOP systems

Principal investigator: dr hab. Katarzyna Małgorzata Targowska-Duda

Uniwersytet Medyczny w Lublinie

Call: SONATA BIS 11, Panel: NZ7

80. Formation of spatial heterogeneities on the plama membrane and their impact on cell signaling

Principal investigator: Marek Kochańczyk

Instytut Podstawowych Problemów Techniki Polska Akademia Nauk

Call: PRELUDIUM 5, Panel: NZ2

81. Source apportionment of severe particulate matter air pollution events in selected Polish cities

Principal investigator: dr hab. Katarzyna Krystyna Juda-Rezler

Politechnika Warszawska, Wydział Inżynierii Środowiska

Call: OPUS 2, Panel: ST10

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