Search results

1. The influence of muscarinic acetylcholine receptors (M1, M4 and M5) and serotonergic 5-HT1A receptor modulation on cogni…

Principal investigator: dr Paulina Agnieszka Cieślik

Instytut Farmakologii PAN

Call: PRELUDIUM 16, Panel: NZ7

2. Positioning the aryl hydrocarbon receptor (AhR) as a new target for pharmacotherapy of sporadic Alzheimer disease: verif…

Principal investigator: prof. Małgorzata Kajta

Instytut Farmakologii PAN

Call: OPUS 28, Panel: NZ7

3. The new homology model of H3 histaminic receptor - structure, interaction with ligand

Principal investigator: Jakub Józef Jończyk

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 8, Panel: NZ7

4. Investigation of molecular mechanisms of rapid antidepressant action of NLX-101, a biased agonist of the 5-HT1A receptor…

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Call: OPUS 18, Panel: NZ7

5. The evaluation of the efficacy of alpha7 nicotinic acetylcholine receptor ligands in rat models of autism

Principal investigator: dr hab. Agnieszka Anna Nikiforuk

Instytut Farmakologii PAN

Call: OPUS 12, Panel: NZ7

6. The effects of ligands of the alpha7 nicotinic acetylcholine receptors on complex cognitive processes and social behavio…

Principal investigator: Agnieszka Teresa Potasiewicz

Instytut Farmakologii PAN

Call: PRELUDIUM 8, Panel: NZ7

7. Development of an NK1 receptor homology model based on the data concerning interspecies differences in ligand binding.

Principal investigator: dr Piotr Jakub Lipiński

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: SONATA 12, Panel: NZ7

8. Mechanisms of Antidepressant Action of Psilocybin: The Role of 5-HT2B-5-HT1A Receptor Dimerization and GSK-3β Activation…

Principal investigator: dr hab. Agata Faron-Górecka

Instytut Farmakologii PAN

Call: OPUS 27, Panel: NZ7

9. Dopaminergic modulation of high frequency oscillations in the rat olfactory bulb associated with the NMDA receptor hypof…

Principal investigator: Jacek Wróbel

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: PRELUDIUM 20, Panel: NZ4

10. The role of the estrogen receptor GPER1 in ferroptosis disorders in mouse model of mucopolysaccharidosis type I.

Principal investigator: Magdalena Żabińska

Uniwersytet Gdański

Call: PRELUDIUM 23, Panel: NZ3

11. Evaluation of P2X7 purinergic receptor as a trigger of brain metabolic abnormalities and neuronal degeneration in a mous…

Principal investigator: dr Anna Wilkaniec

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: SONATA BIS 13, Panel: NZ4

12. Searching for the background underlying the neuroprotective effects of the specific agonist of Y2 receptors - NPY(13-36)…

Principal investigator: Łukasz Przykaza

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: PRELUDIUM 17, Panel: NZ4

13. The role of interaction between P1 purine receptors and nitric oxide bioavailability on intrarenal blood circulation and…

Principal investigator: dr hab. Leszek Dobrowolski

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 13, Panel: NZ5

14. The effect of the metabotropic glutamatergic receptor ligands on potentiating the antidepressant-like actvity of scopola…

Principal investigator: Karolina Sylwia Podkowa

Instytut Farmakologii PAN

Call: PRELUDIUM 10, Panel: NZ7

15. Research of mechanisms of antidepressant action of group II and III mGlu receptor ligands and their role in inducing rap…

Principal investigator: dr hab. Agnieszka Pałucha-Poniewiera

Instytut Farmakologii PAN

Call: OPUS 7, Panel: NZ7

16. Effect of falcarinol on kinetics of GABAergic currents in recombinant model of GABAA receptors.

Principal investigator: dr Marta Magdalena Czyżewska

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej, Wydział Lekarski

Call: PRELUDIUM 6, Panel: NZ3

17. Development of cellular models for the investigation of histamine H3 and H4 receptors pharmacology.

Principal investigator: Tadeusz Piotr Karcz

Uniwersytet Jagielloński- Collegium Medicum, Uniwersytet Jagielloński - Collegium Medicum; Wydział Farmaceutyczny z Oddziałem Analityki Medycznej

Call: PRELUDIUM 1, Panel: NZ4

18. The effect of chronic administration of purine P1-A2B receptor agonist, using electrospun microfibers, on intrarenal blo…

Principal investigator: Joanna Dorota Sitek-Dębska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: PRELUDIUM 21, Panel: NZ5

19. Flavonoid phytoprogestins as novel non-steroidal progesterone receptor modulators in a nutraceutical approach to endomet…

Principal investigator: Agata Gołąbek-Grenda

Uniwersytet Przyrodniczy w Poznaniu

Call: PRELUDIUM 24, Panel: NZ9

20. Molecular mechanism of anticancer action of selected NSAIDs as a PPAR gamma receptor agonists in experimental models of …

Principal investigator: Adam Kazberuk

Uniwersytet Medyczny w Białymstoku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Call: PRELUDIUM 14, Panel: NZ7

21. The role of RAGE, receptor for advanced glycation end-products, in the progressive spinal motor neuron degeneration in f…

Principal investigator: prof. Joanna Alicja Wojtkiewicz

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Lekarski

Call: OPUS 13, Panel: NZ4

22. Functional dissection of three alpha(1)-adrenergic receptor subtypes in the effects of antidepressant drugs: exploitatio…

Principal investigator: prof. Irena Maria Nalepa

Instytut Farmakologii PAN

Call: OPUS 9, Panel: NZ7

23. The influence of 5-HT7 and NMDA receptor ligands with possible antidepressive properties on the activity of rat dorsal r…

Principal investigator: prof. Grzegorz Władysław Hess

Instytut Farmakologii PAN

Call: OPUS 6, Panel: NZ4

24. The role of sphingosine-1-phosphate (S1P) receptors signaling in animal model of Parkinson disease. Searching of novel t…

Principal investigator: Joanna Agata Motyl

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: PRELUDIUM 5, Panel: NZ4

25. The influence of some selected antiepileptic drugs in combination with arachinodyl-2-chlorethylamide, a selective cannab…

Principal investigator: dr Marta Andres-Mach

Instytut Medycyny Wsi im. Witolda Chodźki

Call: OPUS 3, Panel: NZ7

26. Mechanisms of anti-aterosclerotic action of Mas receptor stimulation for angiotensin 1-7 in mouse model of atheroscleros…

Principal investigator: Dominik Stanisław Skiba

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

Call: PRELUDIUM 2, Panel: NZ4

27. An immunoassay combined with chromatography followed by multivariate receptor modelling techniques for source tracking o…

Principal investigator: Marta Ewelina Kobusińska

Uniwersytet Gdański, Wydział Oceanografii i Geografii

Call: PRELUDIUM 12, Panel: ST10

28. Effects of ketamine optical isomers on motivation and decision-making in rats using deep learning for behavioral analysi…

Principal investigator: dr Natalia Alicja Malikowska-Racia

Instytut Farmakologii PAN

Call: SONATA 20, Panel: NZ7

29. Novel role of peroxisome proliferator-activated receptor α in the regulationof amyloid β peptide metabolism and mitochon…

Principal investigator: dr Sylwia Żulińska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: PRELUDIUM 18, Panel: NZ4

30. Molecular modeling of allosteric binding and allosteric-orthosteric coupling in cannabinoid receptor CB1

Principal investigator: Jakub Jakub Jakowiecki

Uniwersytet Warszawski, Wydział Chemii

Call: PRELUDIUM 12, Panel: NZ1

31. Involvement of P2 receptors in pathogenesis of glomerular filtration barrier dysfunction in experimental model of diabet…

Principal investigator: prof. Maciej Wojciech Jankowski

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Call: OPUS 12, Panel: NZ5

32. Investigation of the mechanisms of the neuroprotective effect of group II metabotropic receptors (mGluR2/3) agonist in a…

Principal investigator: dr Ewelina Małgorzata Bratek

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: PRELUDIUM 12, Panel: NZ7

33. Piperazine derivatives as active histamine H3 receptor ligands - molecular modeling, synthesis, pharmacological evaluati…

Principal investigator: Katarzyna Anna Szczepańska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 12, Panel: NZ7

34. Contribution of glutaminergic NMDA receptor to the mechanisms of nanosilver neurotoxicity in vivo

Principal investigator: prof. Lidia Marta Strużyńska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 11, Panel: NZ7

35. The effect of probiotic bacteria and Toll-like receptors ligands on growth and differentiation of intestinal epithelial …

Principal investigator: dr hab. Małgorzata Krystyna Pierzchalska

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Technologii Żywności

Call: OPUS 5, Panel: NZ9

36. The role of ATP-dependent activation of P2 purinergic receptors in the energetic disturbances in the brain of autistic-l…

Principal investigator: Lidia Maria Babiec

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: PRELUDIUM 20, Panel: NZ4

37. Searching for effective strategies to protect neuronal cells against hypoxia and ischemia: Identification of neuroprotec…

Principal investigator: prof. Małgorzata Kajta

Instytut Farmakologii PAN

Call: OPUS 16, Panel: NZ7

38. Amine derivatives of hydantoin as selective 5-HT7 receptor ligand. Molecular modeling, synthesis and pharmacological eva…

Principal investigator: Katarzyna Maria Kucwaj-Brysz

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum Uniwersytet Jagielloński; Wydział Farmaceutyczny

Call: PRELUDIUM 8, Panel: NZ7

39. Role of opioid receptors in arterial hypertension. Examination of hypotensive action of biphalin, a synthetic non-addtic…

Principal investigator: prof. Janusz Bogumił Sadowski

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 2, Panel: NZ4

40. The function of EBI2 receptor in human oligodendrocytes and its role in the cuprizone model for demyelination.

Principal investigator: dr Aleksandra Rutkowska

Gdański Uniwersytet Medyczny, Wydział Lekarski

Call: POLONEZ 2, Panel: NZ3

41. Molecular receptors as a tool for studies of interactions agonist/antagonist of H1 - H4 receptors

Principal investigator: Małgorzata Ewa Walczak

Politechnika Łódzka, Wydział Chemiczny

Call: PRELUDIUM 11, Panel: ST5

42. The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopami…

Principal investigator: dr Katarzyna Maria Kucwaj-Brysz

Uniwersytet Jagielloński, Collegium Medicum

Call: SONATA 17, Panel: NZ7

43. Participation of transient receptor potential (TRP) channels premeable for calcium ions in memory formation and retrieva…

Principal investigator: dr hab. Elżbieta Jolanta Salińska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 8, Panel: NZ4

44. The effects of positive allosteric modulators of alpha7 nicotinic acetylcholine receptors on complex cognitive processes…

Principal investigator: dr hab. Agnieszka Anna Nikiforuk

Instytut Farmakologii PAN

Call: OPUS 4, Panel: NZ7

45. In the search for active compounds among ligands of serotonin, particularly 5-HT7, and dopamine receptors, with potentia…

Principal investigator: prof. Anna Małgorzata Wesołowska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 1, Panel: NZ4

46. The evaluation of therapeutic potential of β-caryophyllene in animal schizophrenia model - behavioral and molecular stud…

Principal investigator: dr Magdalena Białoń

Instytut Farmakologii PAN

Call: PRELUDIUM 21, Panel: NZ7

47. Biased inverse agonists of 5-HT6 receptor and dual 5-HT6/MAO-B inhibitors - in search for new therapeutic approaches for…

Principal investigator: prof. Paweł Maria Zajdel

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 11, Panel: NZ7

48. The role of the neuron-microglia CX3CL1-CX3CR1 and CD200-CD200R protein systems in molecular mechanisms of antipsychotic…

Principal investigator: prof. Agnieszka Basta-Kaim

Instytut Farmakologii PAN

Call: OPUS 10, Panel: NZ7

49. A virtual screening protocol based on automatically generated structure-based pharmacophore models.

Principal investigator: Stefan Mateusz Mordalski

Instytut Farmakologii PAN

Call: HARMONIA 7, Panel: NZ2

50. Investigation of the effects and mechanisms of action of Deep Brain Stimulation in two animal models of treatment-resist…

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Call: OPUS 9, Panel: NZ7

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