Projects funded by the NCN

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107 projects found matching your search criteria :

  1. Synthesis and pharmacological evaluation of novel benzizoxazolepropylpyrolidine derivatives as multifunctional ligands w...

    Call: SONATA 8 , Panel: NZ7

    Principal investigator: dr Monika Emilia Marcinkowska

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  2. Novel dual PDE4 and PDE7 inhibitors in a group of purine and deazapurine derivatives - perspective for the treatment of ...

    Call: OPUS 8 , Panel: NZ7

    Principal investigator: prof. Maciej Henryk Pawłowski

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  3. Targeting peripheral cannabinoid receptors CB2 as a novel therapy to treat osteoarthritis

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Maria Starowicz-Bubak

    Instytut Farmakologii PAN

  4. Neurochemical properties and biological activity of synthetic cathinones (beta-ketoamphetamines) - the psychostimulant "...

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: prof. Jolanta Barbara Zawilska

    Uniwersytet Medyczny w Łodzi, Wydział Farmaceutyczny

  5. Evaluation of the role of transcription factor CREB in the mechanisms antidepressant treatment: study on the novel genet...

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr Grzegorz Kreiner

    Instytut Farmakologii PAN

  6. Pharmacokinetic profiling to understand differences in biological activity of two novel liver-selective NO-releasing com...

    Call: PRELUDIUM 6 , Panel: NZ7

    Principal investigator: dr Kamil Krzysztof Kuś

    Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

  7. Search for novel mechanisms underlining inhibition of cancer cell proliferation by plant-derived nutraceuticals

    Call: SONATA 6 , Panel: NZ7

    Principal investigator: dr hab. Anna Lewińska

    Uniwersytet Rzeszowski

  8. The effect of the novel atypical neuroleptics on the activity and expression of cytochrome P450 isoforms in human liver

    Call: OPUS 6 , Panel: NZ7

    Principal investigator: dr hab. Jacek Wójcikowski

    Instytut Farmakologii PAN

  9. Mechanistic study on enantioseparations of the novel oxazolidinones

    Call: SONATA 6 , Panel: NZ7

    Principal investigator: dr Katarzyna Irena Michalska

    Narodowy Instytut Leków

  10. Sensitization of cancer cells to chemotherapy by novel DNA repair inhibitors

    Call: OPUS 6 , Panel: NZ7

    Principal investigator: dr hab. Tomasz Popławski

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  11. Endogenous enkephalinase inhibitors and their novel synthetic analogs as potential new therapeutics for the treatment of...

    Call: OPUS 6 , Panel: NZ7

    Principal investigator: dr hab. Jakub Jerzy Fichna

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  12. Novel peptide inhibitors of dipeptidyl peptidase IV (DPP IV) as novel approach for diabetes type 2 and inflammatory bowe...

    Call: PRELUDIUM 6 , Panel: NZ7

    Principal investigator: Maciej Stanisław Sałaga

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  13. Synthesis and pharmacological characterization of novel cyclic opioid peptide analogs incorporating fluoro amino acids.

    Call: PRELUDIUM 5 , Panel: NZ7

    Principal investigator: dr Justyna Piekielna-Ciesielska

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  14. Analysis of the structural and functional mechanisms of action of the nicotinic receptors modulators.

    Call: SONATA 5 , Panel: NZ7

    Principal investigator: dr Katarzyna Małgorzata Targowska-Duda

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny z Oddziałem Analityki Medycznej

  15. Synthesis and antifungal activity novel derivatives of quinoline

    Call: PRELUDIUM 4 , Panel: NZ7

    Principal investigator: dr Wioleta Ilona Cieślik

    UNIWERSYTET ŚLĄSKI, Wydział Matematyki, Fizyki i Chemii

  16. Search of novel multifunctional ligands targeting neurodegereneration processes.

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: prof. Barbara Antonina Malawska

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  17. Design, synthesis and biological evaluation of novel functionalized batracylin conjugates

    Call: OPUS 3 , Panel: NZ7

    Principal investigator: prof. Krystyna Jolanta Dzierzbicka

    Politechnika Gdańska, Wydział Chemiczny

  18. Synthesis and physical-chemical properties of novel dendrimeric porphyrazines of potential usage in medicine and bionano...

    Call: SONATA BIS 1 , Panel: NZ7

    Principal investigator: dr hab. Tomasz Adam Gośliński

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  19. Novel bone-related morphological and nanobiomechanical factors driving calvarial development in children with rare crani...

    Call: PRELUDIUM 24 , Panel: NZ7

    Principal investigator: Jolanta Jadwiga Rajca

    UNIWERSYTET ŚLĄSKI

  20. Dual-Target Compounds Modulating EAAT2 and Kv7.2/3 Channels: A Rational Strategy Toward Novel Antiseizure and Antinocice...

    Call: OPUS 29 , Panel: NZ7

    Principal investigator: dr Michał Andrzej Abram

    Uniwersytet Jagielloński

  21. Development of novel 1,3-selenazol-2-one derivatives incorporated into self-emulsifying drug delivery systems as a strat...

    Call: OPUS 29 , Panel: NZ7

    Principal investigator: dr hab. Robert Czarnomysy

    Uniwersytet Medyczny w Białymstoku

  22. The JAK/STAT pathway as a molecular contributor to the development of endometriosis: therapeutic potential of JAK inhibi...

    Call: PRELUDIUM 24 , Panel: NZ7

    Principal investigator: Aleksander Radosław Rycerz

    Uniwersytet Medyczny w Łodzi

  23. Novel covalent modulators of plasma kallikrein activity

    Call: PRELUDIUM 24 , Panel: NZ7

    Principal investigator: Jan Konopka

    Uniwersytet Jagielloński

  24. Disrupting the Toxic NMDAR/TRPM4 Protein Dialogue as a Novel Neuroprotective Strategy: Development of Small-Molecule Inh...

    Call: PRELUDIUM 24 , Panel: NZ7

    Principal investigator: Katarzyna Aleksandra Szafrańska

    Uniwersytet Jagielloński

  25. Canonical and non-canonical roles of DDK in oncogenesis: a cornerstone for the development of novel, potent anticancer t...

    Call: SONATA BIS 14 , Panel: NZ3

    Principal investigator: dr Jan Marian Suski

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  26. Decoding novel O/K loci of Klebsiella pneumoniae into chemical O/K antigen structures – towards better adjustment of bac...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: prof. Jolanta Katarzyna Łukasiewicz

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  27. Development of novel potential therapeutics in inflammatory bowel diseases based on nanoformulations employing senomodul...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: prof. Jakub Jerzy Fichna

    Uniwersytet Medyczny w Łodzi

  28. Synthesis of novel hybrid nanomaterials based on fullerene scaffold for photodynamic therapy of cancer

    Call: PRELUDIUM 23 , Panel: NZ7

    Principal investigator: Dominik Jakub Dreszer

    UNIWERSYTET ŚLĄSKI

  29. The novel analytical technique of evaluation and imaging of the progress of selected chemical reactions assisted by MW/U...

    Call: PRELUDIUM 23 , Panel: NZ7

    Principal investigator: Alina Cherniienko

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  30. Development and characterization of novel multitargeted organometallic tubulin polymerization inhibitors for enhancing t...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: dr hab. Damian Nestor Plażuk

    Uniwersytet Łódzki

  31. The inhibition of NMDAR and TRPM4 coupling - a hope for novel therapeutic target for the treatment of the ischemic brain...

    Call: SONATA BIS 13 , Panel: NZ7

    Principal investigator: dr Bartosz Sebastian Pomierny

    Uniwersytet Jagielloński, Collegium Medicum

  32. Directed screening and evaluation of novel bactericidal compounds active againsttubercle bacilli and Mycobacterium absce...

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: prof. Jarosław Dziadek

    Instytut Biologii Medycznej PAN

  33. Search for novel IKK-β inhibitors in the context of diseases with neuroinflammatory origin – structure-based drug design...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Emilia Aleksandra Sługocka

    Uniwersytet Jagielloński, Collegium Medicum

  34. Targeting Energy Metabolism for Precision Cancer Therapy: Novel Inhibitors of LDH-A and PDK1 as Potential Strategies to ...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Marika Anna Frańczak

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  35. Endothelial bioenergetics as a novel target for vascular protection – unveiling the mitochondrial mechanisms of lipid-lo...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: dr Alicja Małgorzata Braczko

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  36. The Role of the Mitochondrial Unfolded Protein Response (UPRmt) in Endothelial Function: a Possible Novel Target for the...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Sylwester Tycjan Mosiołek

    Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

  37. Selective PPARγ modulation by amorfrutin B as a novel therapeutic approach to chemotherapy-induced damage to mammalian b...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Bernadeta Angelika Pietrzak-Wawrzyńska

    Instytut Farmakologii PAN

  38. Development of novel anti-cancer immunotherapy against mesothelioma comprising of oncolytic adenovirus vectors armed wit...

    Call: SONATA 18 , Panel: NZ7

    Principal investigator: dr Łukasz Kuryk

    Narodowy Instytut Zdrowia Publicznego - Państwowy Zakład Higieny (NIZP - PZH)

  39. Gaining control on XBP1s signaling as a starting point for novel cancer therapies

    Call: OPUS 24 , Panel: NZ7

    Principal investigator: prof. Rafał Artur Bartoszewski

    Uniwersytet Wrocławski, Wydział Biotechnologii

  40. Novel mechanism of lead toxicity - a perspective of molecular biology

    Call: SONATA 2 , Panel: NZ7

    Principal investigator: dr Natalia Pawlas

    Instytut Medycyny Pracy i Zdrowia Środowiskowego

  41. The advanced novel materials for effective bleeding and antimicrobial control in TCCC (Tactical Combat Casualty Care) an...

    Call: SONATA 18 , Panel: NZ7

    Principal investigator: dr Dorota Anna Chełminiak-Dudkiewicz

    Uniwersytet Mikołaja Kopernika, Wydział Chemii

  42. Studies on the post-receptor mechanisms of TSPO in search of a novel therapeutic target of metabolic syndrome

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: dr Łukasz Kurach

    Uniwersytet Medyczny w Lublinie

  43. MOF-antidote": Novel detoxification materials based on metal organic-frameworks for drugs of abuse removal - synthesis, ...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Przemysław Jakub Jodłowski

    Politechnika Krakowska im. Tadeusza Kościuszki

  44. Novel broad-spectrum central nervous system active substances: optimization of their multi-target profile

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Anna Kaczor

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

  45. Search for Inhibitors of Human δ1-Pyrroline-5-Carboxylate Reductase 1 (PYCR1) as Lead Molecules for the Development of N...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Miłosz Ruszkowski

    Instytut Chemii Bioorganicznej PAN

  46. Non-provitamin A carotenoids as a novel therapeutic strategy in intestinal failure associated liver disease (IFALD)

    Call: PRELUDIUM BIS 3 , Panel: NZ7

    Principal investigator: dr hab. Maciej Jan Stawny

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  47. New post-treatment strategy against stroke and perinatal asphyxia – a novel approach based on a selective activation of ...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Agnieszka Wnuk

    Instytut Farmakologii PAN

  48. The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopami...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Katarzyna Maria Kucwaj-Brysz

    Uniwersytet Jagielloński, Collegium Medicum

  49. Antithrombotic, haemodynamic and redox effects of novel HNO donors

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Karol Franciszek Kramkowski

    Uniwersytet Medyczny w Białymstoku

  50. Extracellular vesicles produced by Bifidobacterium as novel approach fortreatment of allergy diseases

    Call: OPUS 22 (LAP) , Panel: NZ7

    Principal investigator: dr hab. Sabina Barbara Górska

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

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