Zmiana języka

Projects search

Identification of novel therapies potentiating the efficacy of immunotherapy with anti-CD20 antibodies in in vivo models.

2015/18/E/NZ6/00702

Keywords

Descriptors

  • NZ6_2: Immunologia kliniczna
  • NZ6_1: Odporność swoista i nieswoista

Panel

NZ6 – Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Magdalena Winiarska

Number of co-investigators in the project: 6

Call

SONATA BIS 5 – announced on 2015-06-15

Amount awarded
1 996 420 PLN
Project start date
2016-04-08
Project end date
2023-04-07
Project duration
84 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Cytometr przeplywowy 3-laserowy z podajnikiem. Cost: 350 000 PLN
  2. HTS podajnik do płytek do cytometru Canto. Cost: 83 640 PLN
  3. Licencja FlowJo (2 pcs). Cost: 20 000 PLN
  4. Licencja Graphpad/CDR.

Information in the final report

Publication in academic press/journals (4)

  1. Selective inhibition of HDAC6 sensitizes cutaneous T cell lymphoma cells to PI3K inhibitors

    Authors:
    Malgorzata Bobrowicz, Aleksander Slusarczyk, Joanna Stachura, Michal Dwojak, Desislava Ignatova, Yun-Tsan Chang, Christoph Iselin, Nina Miazek-Zapala, Katsiaryna Marhelava, Emmanuella Guenova, Magdalena Winiarska
    Academic press:
    Oncology Letters (year: 2020, volume: 20(1), pages: 533-540), Publisher: Spandidos Publications
    Status:
    Published
    DOI:
    10.3892/ol.2020.11587 – link to the publication

  2. FOXO1 promotes resistance of non-Hodgkin lymphomas to anti-CD20-based therapy

    Authors:
    Pyrzynska B, Dwojak M, Zerrouqi A, Morlino G, Zapala P, Miazek N, Zagozdzon A, Bojarczuk K, Bobrowicz M, Siernicka M, Machnicki MM, Gobessi S, Barankiewicz J, Lech-Maranda E, Efremov DG, Juszczynski P, Calado D, Golab J, Winiarska M.
    Academic press:
    OncoImmunology (year: 2018, volume: 7, pages: 1423183-1 - 1423183-9), Publisher: Taylor and Francis Online
    Status:
    Published
    DOI:
    10.1080/2162402X.2017.1423183 – link to the publication

  3. CD37 in B Cell Derived Tumors—More than Just a Docking Point for Monoclonal Antibodies

    Authors:
    Malgorzata Bobrowicz, Matylda Kubacz, Aleksander Slusarczyk and Magdalena Winiarska
    Academic press:
    Int. J. Mol. Sci. (year: 2020, volume: 21(24), pages: 46038), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21249531 – link to the publication

  4. HDAC6 inhibition up-regulates CD20 levels and increases the efficacy of anti-CD20 monoclonal antibodies

    Authors:
    Bobrowicz M, Dwojak M, Pyrzynska B, Stachura J, Muchowicz A, Berthel E, Dalla Venezia N, Kozikowski M, Siernicka M, Miazek N, Zapala P, Domagala A, Bojarczuk K, Malenda A, Barankiewicz J, Graczyk-Jarzynka A, Zagozdzon A, Gabrysiak M, Diaz JJ, Karp M, Lech-Maranda E, Firczuk M, Giannopoulos K, Efremov DG, Laurenti L, Baatout D, Frenzel L, Malinowska A, Slabicki M, Zenz T, Zerrouqi A, Golab J, Winiarska M.
    Academic press:
    Blood (year: 2017, volume: 130(14), pages: 1628-1638), Publisher: American Society of Hematology
    Status:
    Published
    DOI:
    10.1182/blood-2016-08-736066 – link to the publication

« New search

Graphic design and implementation: Jakub Piotrowski