Search results

1. Halogen Bonding in Protein-Ligand Complexes. Thermodynamics and Structural Studies on Rationally Selected Protein-Ligand…

Principal investigator: prof. Jarosław Poznański

Instytut Biochemii i Biofizyki PAN

Call: OPUS 4, Panel: ST4

2. Crystallographic analysis of RNA-ligand complexes. Towards rational design oflead compounds for development of therapies…

Principal investigator: dr hab. Agnieszka Ludmiła Kiliszek

Instytut Chemii Bioorganicznej PAN

Call: OPUS 23, Panel: NZ7

3. Anilide derivatives of long-chain cyclic amines as multifunctional serotonin receptors ligands and phosphodiesterase 7 i…

Principal investigator: dr Agnieszka Wioleta Jankowska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 13, Panel: NZ7

4. Development of novel anti-cancer immunotherapy against mesothelioma comprising of oncolytic adenovirus vectors armed wit…

Principal investigator: dr Łukasz Kuryk

Narodowy Instytut Zdrowia Publicznego - Państwowy Zakład Higieny (NIZP - PZH)

Call: SONATA 18, Panel: NZ7

5. Allosteric and allosteric-orthosteric bitopic ligands of histamine receptor H4 as a way to increase selectivity and bias…

Principal investigator: prof. Sławomir Hubert Filipek

Uniwersytet Warszawski, Wydział Chemii

Call: OPUS 23, Panel: NZ7

6. Search for new "drug-like" molecules designed as adenosine receptors ligands

Principal investigator: prof. Katarzyna Justyna Kieć-Kononowicz

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: HARMONIA 2, Panel: NZ4

7. Non-noble metal complexes bearing NHC ligands from renewable feedstocks as catalysts for sustainable synthesis of functi…

Principal investigator: dr hab. Patrycja Karolina Żak

Uniwersytet im. Adama Mickiewicza w Poznaniu

Call: OPUS 29, Panel: ST5

8. Design and Pharmacological Evaluation of Marine Alkaloid-Inspired 5-HT2A Receptor Ligands

Principal investigator: Szymon Kazimierz Kordylewski

Instytut Farmakologii PAN

Call: PRELUDIUM 24, Panel: NZ1

9. Synthesis of ruthenium complexes with CAAC ligands, application in metathesis reactions

Principal investigator: dr Adrian Sytniczuk

Uniwersytet Warszawski

Call: SONATA 20, Panel: ST4

10. Playing with Carbene Ligand Rigidity to Control Olefin Metathesis Stability, Productivity and Selectivity

Principal investigator: prof. Karol Lesław Grela

Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

Call: OPUS 26, Panel: ST4

11. Thermodynamic contribution of halogen bonds in protein-ligand systems. Design, synthesis, and thermodynamic studies of m…

Principal investigator: dr Sławomir Jan Kasperowicz

Instytut Biochemii i Biofizyki PAN

Call: PRELUDIUM 21, Panel: ST4

12. Metallosupramolecular architectures based on flexidentate pyridyl-β-diketonate ligands - synthesis, properties and catal…

Principal investigator: Gracjan Piotr Kurpik

Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Zaawansowanych Technologii

Call: PRELUDIUM 21, Panel: ST4

13. The new methodology for better understanding of ligand-RNA interactions.

Principal investigator: dr Filip Artur Stefaniak

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: OPUS 20, Panel: NZ2

14. Silsesquioxanes as Multifunctional Ligands in Coordination Chemistry and Nano-Building Blocks for Hybrid Materials

Principal investigator: dr hab. Łukasz John

Uniwersytet Wrocławski, Wydział Chemii

Call: OPUS 20, Panel: ST4

15. Anti-cancer strategy based on the induced G-quadruplex formation. Structural and biological properties of ligand-RNA/mRN…

Principal investigator: dr Dorota Gudanis-Sobocińska

Instytut Chemii Bioorganicznej PAN

Call: SONATA 16, Panel: ST4

16. New 5-HT6 receptor ligands from the group of sulfonamide derivatives of cyclic arylguanidines in the treatment of gliobl…

Principal investigator: dr Przemysław Patryk Zaręba

Politechnika Krakowska im. Tadeusza Kościuszki, Wydział Inżynierii i Technologii Chemicznej

Call: PRELUDIUM 19, Panel: NZ7

17. New multifunctional drug-like ligands focusing on molecular targets associated with the symptoms and causes of Alzheimer…

Principal investigator: Anna Marta Pasieka

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 19, Panel: NZ7

18. Novel approach in the search for asthma and COPD therapies - computer aided design of multi-target-directed ligands bloc…

Principal investigator: Alicja Aleksandra Gawalska

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 19, Panel: NZ7

19. Seeking for CB1 and CB2 receptor ligands among drugs, drug metabolites, and phytochemical compounds

Principal investigator: Adam Stasiulewicz

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: PRELUDIUM 18, Panel: NZ7

20. Study on the structure related dielectric properties and molecular dynamics of poly(dimethylsiloxane) crosslinked by met…

Principal investigator: Angelika Kinga Wrzesińska

Politechnika Łódzka, Wydział Chemiczny

Call: PRELUDIUM 17, Panel: ST3

21. Therapeutic potential of biased 5-HT7 receptor ligands in the treatment of depression

Principal investigator: prof. Paweł Maria Zajdel

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 17, Panel: NZ7

22. Novel hybrid 5-HT6 serotonin receptor and SERT transporter ligands as a therapeutic perspective of behavioural and cogni…

Principal investigator: dr Agata Siwek

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: SONATA 14, Panel: NZ7

23. Development of a group of non-basic ligands of serotonin receptor 5-HT7, derivatives of 2-(6-oxo-3-phenyl-1,6-dihydropyr…

Principal investigator: dr Sabina Marta Podlewska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: SONATINA 2, Panel: NZ7

24. Diet and human gut microbiome as sources of N-acyl amines acting as GPCR ligands.

Principal investigator: dr Anna Katarzyna Drzazga

Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

Call: SONATINA 2, Panel: NZ9

25. Synthesis of ruthenium complexes bearing CAAC ligands and their use in metathesis reactions

Principal investigator: dr hab. Anna Kajetanowicz

Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

Call: OPUS 14, Panel: ST5

26. Novel multi-target ligands of aminergic GPCRs as pharmacological tools to study the pathomechanism of schzophrenia

Principal investigator: dr hab. Agnieszka Anna Kaczor

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

Call: OPUS 14, Panel: NZ7

27. Mechanisms of binding and transport in plasma of amyloid beta oligomers by human serum albumin (HSA) in presence of sele…

Principal investigator: prof. Maciej Leszek Kozak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

Call: OPUS 14, Panel: ST4

28. Enlarged aceneporphyrinoids - multitopic ligands with tunable binding properties

Principal investigator: dr Bartosz Szyszko

Uniwersytet Wrocławski, Wydział Chemii

Call: SONATA 13, Panel: ST5

29. From novel rhenium(I) complexes with triimine ligands towards more efficient photo- and electroluminescence materials

Principal investigator: prof. Barbara Elżbieta Machura

UNIWERSYTET ŚLĄSKI, Wydział Nauk Ścisłych i Technicznych

Call: OPUS 13, Panel: ST5

30. Influence of the hydroxamate ligands' structure on the thermodynamic properties of metallacrown complexes.

Principal investigator: Małgorzata Ostrowska

Uniwersytet Wrocławski, Wydział Chemii

Call: PRELUDIUM 13, Panel: ST5

31. New pathways for functionalization of phosphorus-rich ligands

Principal investigator: Anna Ordyszewska

Politechnika Gdańska, Wydział Chemiczny

Call: PRELUDIUM 13, Panel: ST5

32. Analysis and evaluation of the effectiveness of anorexic and safety properties for the new histamine H3 receptor ligands

Principal investigator: dr hab. Magdalena Bogumiła Kotańska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 12, Panel: NZ7

33. Studies of the specificity and immunogenicity of baculovirus-obtained recombinant binding region of P. falciparum EBA-18…

Principal investigator: Agata Aleksandra Zerka

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Call: PRELUDIUM 12, Panel: NZ6

34. New platinum and rhodium complexes with bulky N-heterocyclic carbene ligands - synthesis, structure and catalytic activi…

Principal investigator: dr Patrycja Żak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

Call: SONATA 12, Panel: ST5

35. Novel multi-target directed ligands combining cholinesterase inhibition and 5-HT6 antagonism - design, synthesis and pha…

Principal investigator: dr hab. Anna Karolina Więckowska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: SONATA 12, Panel: NZ7

36. Application of approximate non-empirical model based on long-range terms of interaction energy for assessment of inhibit…

Principal investigator: Wiktoria Jedwabny (z d. Giedroyć-Piasecka)

Politechnika Wrocławska, Wydział Chemiczny

Call: PRELUDIUM 11, Panel: ST4

37. Memetic algorithms for the excited ligand diffusion in condensed biological matter

Principal investigator: Jakub Mateusz Rydzewski

Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Call: PRELUDIUM 10, Panel: ST3

38. In vivo and in vitro structure of influenza virus RNA. The structural determinants behind the inhibition of influenza vi…

Principal investigator: prof. Elżbieta Kierzek

Instytut Chemii Bioorganicznej PAN

Call: OPUS 10, Panel: NZ1

39. The new homology model of H3 histaminic receptor - structure, interaction with ligand

Principal investigator: Jakub Józef Jończyk

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 8, Panel: NZ7

40. Synthesis and pharmacological evaluation of novel benzizoxazolepropylpyrolidine derivatives as multifunctional ligands w…

Principal investigator: dr Monika Emilia Marcinkowska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: SONATA 8, Panel: NZ7

41. Halogen bonding - the role and significance in interactions of ligands with class A GPCRs

Principal investigator: dr Rafał Kurczab

Instytut Farmakologii PAN

Call: SONATA 8, Panel: NZ7

42. Unusual 5-HT6 receptor ligands

Principal investigator: prof. Andrzej Jacek Bojarski

Instytut Farmakologii PAN

Call: OPUS 7, Panel: NZ7

43. Characterization of ligand protein interactions and interdomain communication in fungal ABC transporters related to mult…

Principal investigator: dr hab. Marcin Kołaczkowski

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej, Wydział Lekarski

Call: OPUS 6, Panel: NZ6

44. Synthesis of pyridopyrimidine derivatives, dual affinity ligands for 5-HT1AR and SERT.

Principal investigator: prof. Franciszek Herold

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Call: OPUS 6, Panel: NZ7

45. Crystallographic investigation of mammalian serum albumins in complexes with ligands

Principal investigator: dr Anna Danuta Bujacz

Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

Call: OPUS 6, Panel: ST5

46. New copper complexes bearing NHC ligands: synthesis and catalytic application using water as reaction medium.

Principal investigator: dr Anna Szadkowska

Uniwersytet Warszawski, Wydział Chemii

Call: SONATA 4, Panel: ST5

47. Search of novel multifunctional ligands targeting neurodegereneration processes.

Principal investigator: prof. Barbara Antonina Malawska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 4, Panel: NZ7

48. Taylor dispersion analysis in coiled capillaries at high flow rates - new tool in analytical chemistry for determination…

Principal investigator: prof. Robert Hołyst

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Call: OPUS 4, Panel: ST4

49. A new class of P-stereogenic cyclohexane-based diphosphine ligands - effective application of Birch reduction in organop…

Principal investigator: Magdalena Jaklińska

Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Chemii

Call: PRELUDIUM 3, Panel: ST5

50. Probing molecular recognition by mass spectrometry. A case study: Examination of properties of non-covalent complexes of…

Principal investigator: dr Magdalena Zimnicka

Instytut Chemii Organicznej Polska Akademia Nauk

Call: SONATA 2, Panel: ST4

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