Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Taylor dispersion analysis in coiled capillaries at high flow rates - new tool in analytical chemistry for determination of equilibrium constant for the formation of ligand-macromolecule complex.

2012/07/B/ST4/01400

Keywords:

Taylor dispersion analysis ligand-macromolecule complex analytical chemistry

Descriptors:

  • ST4_1:
  • ST4_6:
  • ST4_7:

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Instytut Chemii Fizycznej Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Robert Hołyst 

Number of co-investigators in the project: 3

Call: OPUS 4 - announced on 2012-09-15

Amount awarded: 903 600 PLN

Project start date (Y-m-d): 2013-06-20

Project end date (Y-m-d): 2016-06-19

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. waga analitycza (9 000 PLN)
  2. detektor fluorescencyjny np. RF-20A/20Axs firmy Shimadzu (60 000 PLN)
  3. obiektywy do mikroskopu nikkon.

Information in the final report

  • Publication in academic press/journals (5)
  1. A method for rapid screening of interactions of pharmacologically active compounds with albumin
    Authors:
    Majcher, A ; Lewandrowska, A ; Herold, F ; Stefanowicz, J ; Slowinski, T ; Mazurek, AP ; Wieczorek, SA ; Holyst, R
    Academic press:
    ANALYTICA CHIMICA ACTA (), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.aca.2014.12.008 - link to the publication
  2. A method for rapid screening of interactions of pharmacologically active compounds with albumin
    Authors:
    Majcher, A ; Lewandrowska, A ; Herold, F ; Stefanowicz, J ; Slowinski, T ; Mazurek, AP ; Wieczorek, SA ; Holyst, R
    Academic press:
    ANALYTICA CHIMICA ACTA (rok: 2015, tom: 855, strony: 51-59), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.aca.2014.12.008 - link to the publication
  3. Denaturation of proteins by surfactants studied by the Taylor dispersion analysis
    Authors:
    Anna Zagożdżon, Aldona Jelińska, Marcin Górecki, Agnieszka Wisniewska, Jadwiga Frelek and Robert Hołyst
    Academic press:
    Plos one (rok: 2017, tom: 12, strony: e0175838), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal. - link to the publication
  4. Sterilization of polydimethylsiloxane surface with Chinese herb extract: a new antibiotic mechanism of chlorogenic acid
    Authors:
    Ren Song, Wu Ming, Guo Jiayu, Zhang Wang, Liu Xiaohan, Sun Lili, Holyst Robert, Hou Sen, Fang Yongchun, Feng Xizeng
    Academic press:
    SCIENTIFIC REPORTS (rok: 2015, tom: 5, strony: 10464), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/srep10464 - link to the publication
  5. Gold-Oxoborate Nanocomposites and Their Biomedical Applications
    Authors:
    Wybranska Katarzyna, Paczesny Jan, Serejko, Katarzyna, Sura Karolina, Wlodyga Karolina, Dziecielewski Igor, Jones Samuel, Sliwa Agnieszka, Wybranska Iwona, Holyst Robert, Scherman Oren ,Fialkowski Marcin
    Academic press:
    ACS APPLIED MATERIALS & INTERFACES (rok: 2015, tom: 7, strony: 3931-3939), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/am508979y - link to the publication