Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Search results

496 projects found matching your search criteria :

  1. Selective inhibition of Janus kinases for the treatment of autoimmune hepatitis: Translational PK/PD modelling from mole...

    Call: SONATA 19 , Panel: NZ7

    Principal investigator: dr Artur Świerczek

    Uniwersytet Jagielloński, Collegium Medicum

  2. Inhibitory Functional Networks in Addiction Development within Social Context - a Missing Piece of Puzzle

    Call: OPUS 26 , Panel: NZ4

    Principal investigator: dr Marzena Stefaniuk

    Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

  3. Modulation of the N-glycosylation as a tool to improve the CAR-T immunotherapy efficacy

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr Agnieszka Graczyk-Jarzynka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  4. Design and Development of Serine Hydroxymethyltransferase-2 (SHMT2) Inhibitors Blocking Tumor Growth

    Call: SONATA BIS 13 , Panel: NZ7

    Principal investigator: dr hab. Miłosz Ruszkowski

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  5. Synthesis and biological activity evaluation of new hybrid derivatives of tacrine and melatonin as potential cholinester...

    Call: OPUS 2 , Panel: ST5

    Principal investigator: dr Anna Zawadzka

    Uniwersytet Warszawski, Wydział Chemii

  6. Molecular mechanisms of DNA damage triggered by PIM kinases inhibition and its consequences for activation of innate imm...

    Call: OPUS 25 , Panel: NZ5

    Principal investigator: prof. Przemysław Juszczyński

    Instytut Hematologii i Transfuzjologii

  7. Theoretical prediction, chemical synthesis and biological analysis of a novel class of HSPA5 inhibitors

    Call: OPUS 25 , Panel: ST4

    Principal investigator: prof. Arkadiusz Chworoś

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  8. Compounds modulating function of telomeric proteins TRF1 and TRF2

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: prof. Maciej Bagiński

    Politechnika Gdańska, Wydział Chemiczny

  9. Unraveling protease activation in stimulated CAR-T cells to identify new biomarkers for assessing their clinical efficac...

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: dr hab. Małgorzata Firczuk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  10. Development of dual immuno-oligo- biosensors for monitoring and controlling of the metastatic colorectal cancer and inve...

    Call: OPUS 25 , Panel: ST4

    Principal investigator: dr hab. Magdalena Stobiecka

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

  11. Investigating the mechanisms of CD20 downregulation triggered by tyrosine kinase inhibitors in Philadelphia chromosome-p...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Krzysztof Domka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  12. Search for novel IKK-β inhibitors in the context of diseases with neuroinflammatory origin – structure-based drug design...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Emilia Sługocka

    Uniwersytet Jagielloński, Collegium Medicum

  13. Targeting Energy Metabolism for Precision Cancer Therapy: Novel Inhibitors of LDH-A and PDK1 as Potential Strategies to ...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Marika Frańczak

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  14. The design and development of the peptide inhibitors library targeting Zn(II)-binding site of matrix metalloproteinases ...

    Call: PRELUDIUM 22 , Panel: ST5

    Principal investigator: Paulina Potok

    Uniwersytet Wrocławski, Wydział Chemii

  15. Endothelial bioenergetics as a novel target for vascular protection – unveiling the mitochondrial mechanisms of lipid-lo...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Alicja Braczko

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  16. Computational alchemy and experimental validation: a hybrid approach for designing new antimicrobial peptides

    Call: PRELUDIUM 22 , Panel: NZ1

    Principal investigator: Piotr Chyży

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  17. Multiparameter analysis of co-inhibitory and co-stimulatory immune checkpoints and their role in the induction of immuno...

    Call: PRELUDIUM 22 , Panel: NZ6

    Principal investigator: dr Dorota Suszczyk

    Uniwersytet Medyczny w Lublinie

  18. Designing Active Inhibitors of SARS-CoV-2 Methyltransferases

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Alex Matsuda

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  19. Efektywność nowatorskiej terapii inhibitorami JAK u pacjentów z reumatoidalnym zapaleniem stawów w odniesieniu do profil...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Sylwia Biały

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  20. Feel the chemistry if you're close enough - proximity-induced SuFEx ligation for mRNA biology and medicine

    Call: OPUS 25 , Panel: ST5

    Principal investigator: prof. Jacek Jemielity

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  21. Combining microfluidic-assisted biofabrication with high throughput proteomics to unravel skeletal muscle plasticity und...

    Call: SONATINA 7 , Panel: ST5

    Principal investigator: dr Nehar Celikkin

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  22. Electrical stimulation of Anterior Thalamic Nuclei for memory modulation

    Call: POLONEZ BIS 3 , Panel: NZ4

    Principal investigator: dr Maciej Jankowski

    Politechnika Gdańska

  23. Development of novel anti-cancer immunotherapy against mesothelioma comprising of oncolytic adenovirus vectors armed wit...

    Call: SONATA 18 , Panel: NZ7

    Principal investigator: dr Łukasz Kuryk

    Narodowy Instytut Zdrowia Publicznego PZH - Państwowy Instytut Badawczy

  24. Development of a cell-based assay for screening of SARS-CoV-2 PLpro inhibitors

    Call: SONATA 18 , Panel: NZ6

    Principal investigator: dr Wioletta Rut

    Politechnika Wrocławska

  25. Effects of tyrosine kinase inhibitors on Syk pathway in eNOS-based platelet subpopulations and on endothelial barrier in...

    Call: POLONEZ BIS 3 , Panel: NZ7

    Principal investigator: dr hab. Aneta Radziwon-Balicka

    Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

  26. Targeted inhibition of hypusination pathway

    Call: OPUS 24 , Panel: NZ7

    Principal investigator: dr Przemysław Grudnik

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  27. Identification of key structural elements of immunomodulatory proteins - inhibitors of antigenic peptide transporter TAP...

    Call: SONATA 18 , Panel: NZ7

    Principal investigator: dr Natalia Karska

    Uniwersytet Gdański, Wydział Chemii

  28. The role of diet in the development of autoimmune diseases - new interleukin 15 inhibitors among dietary polyphenols and...

    Call: SONATA 18 , Panel: NZ9

    Principal investigator: dr Barbara Żyżyńska-Granica

    Warszawski Uniwersytet Medyczny

  29. RamanSense: Metabolomics based on Enhanced Stimulated Raman Microscopy

    Call: MAESTRO 14 , Panel: ST4

    Principal investigator: prof. Małgorzata Barańska

    Uniwersytet Jagielloński, Wydział Chemii

  30. Computational deciphering of pro-ferroptotic cell death protein machinery as a fundamental step in the search for therap...

    Call: SONATA BIS 12 , Panel: ST4

    Principal investigator: dr Karolina Mikulska-Rumińska

    Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Fizyki, Astronomii i Informatyki Stosowanej

  31. Histone demethylase inhibitors as chemosensitivity modulators in the treatment of head and neck squamous cell carcinoma

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Dawid Dorna

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  32. Selective determination of isoenzymatic lactate dehydrogenase activity in flow analysis format

    Call: PRELUDIUM 21 , Panel: NZ5

    Principal investigator: Justyna Głowacka

    Uniwersytet Warszawski, Wydział Chemii

  33. Rhythms of attention: The functional and causal role of neural oscillations in selective attention.

    Call: OPUS 23 , Panel: HS6

    Principal investigator: dr hab. Dariusz Asanowicz

    Uniwersytet Jagielloński, Wydział Filozoficzny

  34. Mycogenic metal nanoparticles for plant growth stimulation and increased plant production.

    Call: PRELUDIUM 21 , Panel: NZ9

    Principal investigator: Joanna Trzcińska-Wencel

    Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Nauk Biologicznych i Weterynaryjnych

  35. Use of comparative oncology approach to dissect the PD-1 intrinsic signalling in osteosarcoma. Can dog be the key for ne...

    Call: PRELUDIUM 21 , Panel: NZ1

    Principal investigator: Katarzyna Dziubek

    Uniwersytet Gdański, Międzynarodowe Centrum Badań nad Szczepionkami Przeciwnowotworowymi

  36. Mechanisms and therapeutic potential of SGLT2/SGLT1 and NHE-1 inhibition in a rat model of heart failure with preserved ...

    Call: OPUS 23 , Panel: NZ5

    Principal investigator: dr hab. Urszula Mackiewicz

    Centrum Medyczne Kształcenia Podyplomowego

  37. Design, synthesis and in vitro and in vivo studies of anticancer potential of phosphonic and phosphinic analogs of sulfo...

    Call: OPUS 2 , Panel: ST5

    Principal investigator: prof. Tadeusz Gajda

    POLITECHNIKA ŁÓDZKA, Wydział Chemiczny

  38. Combination of FAAH inhibition with action via serotonin 5-HT6 receptor as pioneering approach to fight with Alzheimer D...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Kinga Czarnota-Łydka

    Uniwersytet Jagielloński, Collegium Medicum

  39. Nonlinear effects in human ear stimulated with sound and implant simultaneously.

    Call: PRELUDIUM 21 , Panel: ST8

    Principal investigator: Robert Zabłotni

    Politechnika Lubelska

  40. Pharmacogenomics of SGLT2 inhibitors - investigating the role of empagliflozin in epigenetic modification of non-coding ...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Anna Nowak

    Warszawski Uniwersytet Medyczny

  41. The effects of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors on changes in selected epigenetic mechan...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Agnieszka Woźniak

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  42. Two-component preparations in the treatment of infections caused by pathogenic microorganisms

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Katarzyna Szałapata

    Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Biologii i Biotechnologii

  43. Molecular determinants of input specificity in plasticity phenomena at GABAergic synapses in the hippocampus

    Call: OPUS 22 , Panel: NZ4

    Principal investigator: prof. Jerzy Mozrzymas

    Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

  44. SELECTIVE REGULATION OF RAB GTPASES BY TARGETING PROTEIN-PROTEIN INTERACTIONS BETWEEN RABS AND REGULATORY PROTEINS

    Call: PRELUDIUM BIS 3 , Panel: ST4

    Principal investigator: dr hab. Katarzyna Błażewska

    Politechnika Łódzka, Wydział Chemiczny

  45. Combinatorial targeting of non-genetic sources of cell-to-cell heterogeneity to overcome fractional killing of cancer ce...

    Call: SONATA 17 , Panel: NZ3

    Principal investigator: dr Jarosław Walczak

    Instytut Podstawowych Problemów Techniki Polskiej Akademii Nauk

  46. Algorithmic estimation of eye movements changes in relation to development of Parkinson's disease

    Call: OPUS 2 , Panel: ST6

    Principal investigator: dr hab. Andrzej Przybyszewski

    Polsko-Japońska Akademia Technik Komputerowych

  47. Photophysics and Bimolecular Reactions of Metal Nanoclusters

    Call: OPUS 22 (LAP) , Panel: ST4

    Principal investigator: dr hab. Gonzalo Angulo Nunez

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  48. Radiosensitization by the combined use of modified nucleosides and inhibitors of DNA repair to improve the efficacy of r...

    Call: SONATA 17 , Panel: ST4

    Principal investigator: dr Magdalena Zdrowowicz-Żamojć

    Uniwersytet Gdański, Wydział Chemii

  49. Structure-guided design of histone demethylase inhibitors for cancer therapy.

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Piotr Małecki

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  50. Inhibition of protein disulfide isomerases as a strategy for reduction of prothrombotic state in atherosclerosis; therap...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Kamil Przyborowski

    Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)