Crystallography of DNA repair enzymes as a tool to study substrate specifity and a mechanism of inhibition
2011/01/M/NZ1/05301
Keywords
Descriptors
- NZ1_4: Biologia strukturalna
- NZ1_1: Biologia molekularna
Panel
NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution
Instytut Biochemii i Biofizyki PAN
Voivodeship: mazowieckie
Principal investigator (from the host institution)
Number of co-investigators in the project: 4
Call
HARMONIA 1 – announced on 2011-03-15
- Amount awarded
- 300 000 PLN
- Project start date
- 2011-12-06
- Project end date
- 2014-12-05
- Project duration
- 36 months (the same as in the proposal)
- Project status
- Project settled
Equipment purchased [PL]
- Dewar do przechowywania i transportu kryształów białek. Cost: 5 000 PLN
- Zestaw narzędzi do przechowywania i transportu krzyształów.. Cost: 10 000 PLN
Information in the final report
Publication in academic press/journals (2)
-
Differential repair of etheno-DNA adducts by bacterial and human AlkB proteins
- Authors:
- Daria Zdżalik, Anna Domańska, Paulina Prorok, Konrad Kosicki, Erwin van den Born, Päl Ø Falnes, Carmelo J Rizzo, F. Peter Guengerich, Barbara Tudek
- Academic press:
- DNA Repair (year: 2015, volume: 30, pages: 46032), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.dnarep.2015.02.021. – link to the publication
-
Zinc finger oxidation of Fpg/Nei DNA glycosylases by 2-thioxanthine: biochemical and X-ray structural characterization
- Authors:
- Biela A, Coste F, Culard F, Guerin M, Goffinont S, Gasteiger K, Cieśla J, Winczura A, Kazimierczuk Z, Gasparutto D, Carell T, Tudek B, Castaing B.
- Academic press:
- Nucleic Acids Research (year: 2014, volume: 42, pages: 10748-61), Publisher: Oxford Journals
- Status:
- Published
- DOI:
- 10.1093/nar/gku613 – link to the publication