Inter- and intracellular signalling in innate immune response: experimental and mathematical analysis
2011/03/B/NZ2/00281
Keywords
Descriptors
- NZ2_9: Biologia systemowa
- NZ2_10: Modelowanie i symulacje biologiczne
- NZ3_7: Przekaźnictwo sygnału
Panel
NZ2 – Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology
Host institution
Instytut Podstawowych Problemów Techniki Polska Akademia Nauk
Voivodeship: mazowieckie
Principal investigator (from the host institution)
Number of co-investigators in the project: 6
Call
OPUS 2 – announced on 2011-09-15
- Amount awarded
- 562 761 PLN
- Project start date
- 2012-08-06
- Project end date
- 2016-02-05
- Project duration
- 42 months (the same as in the proposal)
- Project status
- Project settled
Equipment purchased [PL]
- karta wielofunkcyjna DAQ. Cost: 12 000 PLN
- pakiet oprogramowania "LabView". Cost: 10 000 PLN
- trzy komputery klasy PC do obsługi aparatury pomiarowej, analizy danych pomiarowych oraz symulacji numerycznych. Cost: 12 565 PLN
Information in the final report
Publication in academic press/journals (8)
-
Clustering reveals limits of parameter identifiability in multi-parameter models of biochemical dynamic
- Authors:
- Nienałtowski K., Włodarczyk M., Lipniacki T., Komorowski M.
- Academic press:
- BMC SYSTEMS BIOLOGY (year: 2015, volume: 0,420138888888889, pages: 46031), Publisher: BioMed Central
- Status:
- Published
- DOI:
- 10.1186/s12918-015-0205-8 – link to the publication
-
Dynamic cross talk model of the epithelial innate immune response to double-stranded RNA stimulation: coordinated dynamics emerging from cell-level noise
- Authors:
- Bertolusso R, Tian B, Zhao Y, Vergara L, Sabree A, Iwanaszko M, Lipniacki T, Brasier AR, Kimmel M
- Academic press:
- PLOS One (year: 2014, volume: 9, pages: e93396), Publisher: PUBLIC LIBRARY SCIENCE
- Status:
- Published
- DOI:
- 10.1371/journal.pone.0093396 – link to the publication
-
Stability of bacterial toggle switches is enhanced by cell-cycle lengthening by several orders of magnitude
- Authors:
- Jaruszewicz J, Kimmel M, Lipniacki T
- Academic press:
- Physical Review E (year: 2014, volume: 89, pages: 22710), Publisher: AMER PHYSICAL SOC
- Status:
- Published
- DOI:
- 10.1103/PhysRevE.89.022710 – link to the publication
-
Spontaneous NF-κB Activation by Autocrine TNFα Signaling: A Computational Analysis
- Authors:
- Pękalski J, Zuk PJ, Kochańczyk M, Junkin M, Kellog R, Tay S, Lipniacki T
- Academic press:
- PLOS One (year: 2013, volume: 8, pages: e78887), Publisher: PUBLIC LIBRARY SCIENCE
- Status:
- Published
- DOI:
- 10.1371/journal.pone.0078887 – link to the publication
-
Levels of pro-apoptotic regulator Bad and anti-apoptotic regulator Bcl-xL determine the type of the apoptotic logic gate
- Authors:
- Bogdał MN, Hat B, Kochańczyk M, Lipniacki T
- Academic press:
- BMC Systems Biology (year: 2013, volume: 7, pages: 67), Publisher: BIOMED CENTRAL LTD
- Status:
- Published
- DOI:
- 10.1186/1752-0509-7-67 – link to the publication
-
Effective reaction rates in diffusion-limited phosphorylation-dephosphorylation cycles
- Authors:
- Szymańska P, Kochańczyk M, Miękisz J, Lipniacki T
- Academic press:
- Physical Review E (year: 2015, volume: 91, pages: 22702), Publisher: AMER PHYSICAL SOC
- Status:
- Published
- DOI:
- 10.1103/PhysRevE.91.022702 – link to the publication
-
Digital signaling decouples activation probability and population heterogeneity
- Authors:
- RA Kellogg, C Tian, T Lipniacki, SR Quake, S Tay
- Academic press:
- eLife (year: 2015, volume: 4, pages: e08931), Publisher: eLife Sciences Publications LTD
- Status:
- Published
- DOI:
- 10.7554/eLife.08931 – link to the publication
-
Computational Analysis of an Autophagy/Translation Switch Based on Mutual Inhibition of M TORC1 and ULK1
- Authors:
- Szymańska P, Martin KR, MacKeigan JP , Hlavacek WS, Lipniacki T
- Academic press:
- PLOS One (year: 2015, volume: 10, pages: e0116550), Publisher: PUBLIC LIBRARY SCIENCE
- Status:
- Published
- DOI:
- 10.1371/journal.pone.0116550 – link to the publication