Projects funded by the NCN

New perspectives in granulopoiesis regulation: as PAMPs and DAMPs alter the process of iPSCs differentiation towards neu...

Call: OPUS 29 , Panel: NZ6

Principal investigator: dr hab. Joanna Elżbieta Skrzeczyńska-Moncznik

Uniwersytet Jagielloński

Disrupted SorCS2-dependent neuronal protein sorting in neonatal epilepticencephalopathy: functional studies in human iPS...

Call: SONATINA 9 , Panel: NZ5

Principal investigator: dr Aleksandra Tempes

Uniwersytet Warszawski

Topology matters: rationally designed electron and hole transporting materials towards efficient and stable inverted per...

Call: OPUS 28 , Panel: ST5

Principal investigator: dr hab. Daniel Prochowicz

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Multi-omics and functional analyses towards type 2 diabetes: targeting altered pathways and metabolic rearrangements

Call: OPUS 27 , Panel: NZ4

Principal investigator: dr hab. Maciej Maurycy Łałowski

Uniwersytet im. Adama Mickiewicza w Poznaniu

Miniature CRISPR/Cas nucleases for upregulation of utrophin expression: a novel approach for mutation-independent therap...

Call: DAINA 3 , Panel: NZ3

Principal investigator: prof. Józef Dulak

Uniwersytet Jagielloński

Human iPSC-derived cortico-striatal assembloids as a new model to studyneurodevelopmental pathologies induced by mutant ...

Call: OPUS 25 , Panel: NZ3

Principal investigator: dr Magdalena Czeredys

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Modulation of activity of human-specific enhancers in iPSC-derived astrocytes

Call: PRELUDIUM 22 , Panel: NZ2

Principal investigator: Eryk Duński

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

How inactivation of Mitochondrial Calcium Uniporter protects dopaminergic neurons

Call: OPUS 25 , Panel: NZ4

Principal investigator: prof. Jacek Marceli Kuźnicki

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

It takes two to tango_ a decryption of Marfan cardiomyopathy using human iPSC- derived cardiac cells and engineered hear...

Call: OPUS 24 (LAP) , Panel: NZ3

Principal investigator: dr hab. Natalia Rozwadowska

Instytut Genetyki Człowieka PAN

Multiomic level analyses in atypical diabetes patient derived iPSC and pancreatic cells- key to function

Call: POLONEZ BIS 1 , Panel: NZ4

Principal investigator: dr hab. Maciej Maurycy Łałowski

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Identification of molecular mechanism underlying the phenotype development of Emery-Dreifuss muscular dystrophy.

Call: SONATA 17 , Panel: NZ5

Principal investigator: dr Katarzyna Piekarowicz

Uniwersytet Wrocławski, Wydział Biotechnologii

Presymptomatic synaptic disorders in Alzheimer's disease

Call: JPco-fuND2 Call 2021 , Panel: NZ5

Principal investigator: dr Michalina Maria Wężyk

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Novel insights into hydrogen sulfide-mediated cytoprotection - can H2S prevent the progression of Duchenne muscular dyst...

Call: OPUS 18 , Panel: NZ3

Principal investigator: prof. Agnieszka Łoboda

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Functionalized peptide hydrogels as a tool to support skeletal muscle regeneration and therapeutic potential of myogenic...

Call: OPUS 18 , Panel: NZ5

Principal investigator: prof. Maria Anna Ciemerych-Litwinienko

Uniwersytet Warszawski, Wydział Biologii

Molecular and cellular mechanisms of pro-regenerative activity of stem cell- derived extracellular vesicles (EVs) in isc...

Call: MAESTRO 11 , Panel: NZ3

Principal investigator: prof. Ewa Katarzyna Zuba-Surma

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Humanized high-throughput co-culture system for motor neuron diseases

Call: JPND2019 , Panel: NZ3

Principal investigator: prof. Józef Dulak

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Linking abnormal Ca2+ signaling and the unfolded protein response with Huntington's disease pathology in both YAC128 mou...

Call: OPUS 17 , Panel: NZ3

Principal investigator: dr Magdalena Czeredys

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Discovering disorders of brain development in Huntington disease as a consequence of putative total huntingtin deficienc...

Call: OPUS 16 , Panel: NZ3

Principal investigator: dr hab. Maciej Figiel

Instytut Chemii Bioorganicznej PAN

Human spermatogenesis in vitro model for study, diagnosis and treatment of male infertility

Call: OPUS 13 , Panel: NZ5

Principal investigator: dr Natalia Rozwadowska

Instytut Genetyki Człowieka PAN

Mechanisms of cardiovascular complications in rheumatoid arthritis patients: induced pluripotent stem cell-derived cardi...

Call: OPUS 13 , Panel: NZ5

Principal investigator: dr Monika Biniecka

Kardio-Med Silesia Sp. z o.o.

Impaired angiogenesis in Duchenne muscular dystrophy - is there a role for heme oxygenase-1 and statins?

Call: OPUS 11 , Panel: NZ1

Principal investigator: dr hab. Agnieszka Łoboda

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

MicroRNA profiling in cellular models of Huntington's disease generated using iPSC technology

Call: PRELUDIUM 9 , Panel: NZ2

Principal investigator: dr Emilia Barbara Kozłowska

Instytut Chemii Bioorganicznej PAN