Patient-specific iPS cells as a novel approach to study patophysiology of mTOR-related neurodevelopmental disorders
2013/11/D/NZ3/01079
Keywords
Descriptors
- NZ3_5: Neurobiologia molekularna
- NZ3_6: Neurobiologia komórkowa
- NZ3_8: Komórki macierzyste
Panel
NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology
Host institution
Międzynarodowy Instytut Biologii Molekularnej i Komórkowej
Voivodeship: mazowieckie
Principal investigator (from the host institution)
Number of co-investigators in the project: 2
Call
SONATA 6 – announced on 2013-09-16
- Amount awarded
- 700 000 PLN
- Project start date
- 2014-07-11
- Project end date
- 2018-07-10
- Project duration
- 48 months (the same as in the proposal)
- Project status
- Project settled
Information in the final report
Publication in academic press/journals (5)
-
Tuberous sclerosis complex neuropathology requires glutamate-cysteine ligase.
- Authors:
- Anna R. Malik, Ewa Liszewska, Agnieszka Skalecka, Malgorzata Urbanska, Anand M. Iyer, Lukasz J. Swiech, Malgorzata Perycz, Kamil Parobczak, Patrycja Pietruszka, Malgorzata M. Zarebska, Matylda Macias, Katarzyna Kotulska, Julita Borkowska, Wieslawa Grajkowska, Magdalena E. Tyburczy, Sergiusz Jozwiak, David J. Kwiatkowski, Eleonora Aronica and Jacek Jaworski
- Academic press:
- Acta Neuropathologica Communications (year: 2015, volume: 3, pages: 48), Publisher: BioMed Central
- Status:
- Published
- DOI:
- 10.1186/s40478-015-0225-z – link to the publication
-
Matricellular proteins of the Cyr61/CTGF/NOV (CCN) family and the nervous system
- Authors:
- Anna R. Malik , Ewa Liszewska and Jacek Jaworski
- Academic press:
- Frontiers in Cellular Neuroscience (year: 2015, volume: 9, pages: Artykuł 237), Publisher: Frontiers in journal series
- Status:
- Published
- DOI:
- 10.3389/fncel.2015.00237 – link to the publication
-
Adaptor Complex 2 Controls Dendrite Morphology via mTOR-Dependent Expression of GluA2
- Authors:
- Koscielny A, Malik AR, Liszewska E, Zmorzynska J, Tempes A, Tarkowski B, Jaworski J.Koscielny A, Malik AR, Liszewska E, Zmorzynska J, Tempes A, Tarkowski B, Jaworski J.
- Academic press:
- Molecular Neurobiology (year: 2018, volume: 55, pages: 1590-1606), Publisher: Springer International Publishing
- Status:
- Published
- DOI:
- 10.1007/s12035-017-0436-3 – link to the publication
-
mTOR kinase is needed for the development and stabilization of dendritic arbors in newly born olfactory bulb neurons.
- Authors:
- Skalecka A, Liszewska E, Bilinski R, Gkogkas C, Khoutorsky A, Malik AR, Sonenberg N, Jaworski J
- Academic press:
- Developmental Neurobiology (year: 2016, volume: 76(12), pages: 1308-1327), Publisher: Wiley Periodicals
- Status:
- Published
- DOI:
- 10.1002/dneu.22392 – link to the publication
-
Expression of microRNAs miR21, miR146a, and miR155 in tuberous sclerosis complex cortical tubers and their regulation in human astrocytes and SEGA-derived cell cultures.
- Authors:
- van Scheppingen J, Iyer AM, Prabowo AS, Mühlebner A, Anink JJ, Scholl T, Feucht M, Jansen FE, Spliet WG, Krsek P, Zamecnik J, Buccoliero AM, Giordano F, Genitori L, Kotulska K, Jozwiak S, Jaworski J, Liszewska E, van Vliet EA, Aronica E
- Academic press:
- Glia (year: 2016, volume: 64(6), pages: 1066-82), Publisher: Wiley Periodicals
- Status:
- Published
- DOI:
- 10.1002/glia.22983 – link to the publication
Book publications / chapters in book publications (1)
-
Neural stem cell dysfunction in human brain disorders
- Authors:
- Ewa Liszewska, Jacek Jaworski
- Book:
- Human Neural Stem Cells (year: 2018, volume: 66, pages: 283 - 305), Publisher: Springer International Publishing
- Status:
- Published
- DOI:
- link to the publication