Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Mechanisms of cardiovascular complications in rheumatoid arthritis patients: induced pluripotent stem cell-derived cardiomyocytes as an experimental model.

2017/25/B/NZ5/02243

Keywords:

rheumatoid arthritis cardiomyocytes iPSCs technology mitochondrial dysfunctions

Descriptors:

  • NZ5_3: Pathogenesis of human diseases
  • NZ5_5: Diagnostics in human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Monika Biniecka 

Number of co-investigators in the project: 3

Call: OPUS 13 - announced on 2017-03-15

Amount awarded: 1 768 980 PLN

Project start date (Y-m-d): 2018-03-09

Project end date (Y-m-d): 2025-03-08

Project duration:: 36 months (the same as in the proposal)

Project status: Pending project

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. Generation of two hiPSC lines, (DMBi003-A and DMBi004-A), by reprogramming peripheral blood mononuclear cells and fibroblast-like synoviocytes from rheumatoid arthritis patients
    Authors:
    Jan Wolnik, Grzegorz Kubiak, Marta Skoczynska, Piotr Wiland, Ursula Fearon, Douglas Veale, Jozef Dulak, Monika Biniecka
    Academic press:
    Stem Cell Research (rok: 2022, tom: 64, strony: 102886), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.scr.2022.102886 - link to the publication
  2. Komórki macierzyste w medycynie: możliwości, nadzieje, kontrowersje
    Authors:
    Biniecka Monika, Kulik Klaudia, Langrzyk Agnieszka, Wiśniewska Ewa, Dulak Józef
    Academic press:
    Medycyna po Dyplomie (rok: 2019, tom: Marzec, strony: 75-84), Wydawca: Medical Tribune Polska Sp. z o.o.
    Status:
    Published
    DOI:
    brak - link to the publication
  3. The fundamental discoveries in oxygen sensing: implications for heart diseases and cardiomyocytes maturation
    Authors:
    Biniecka Monika, Wolnik Jan, Dulak Józef
    Academic press:
    KOSMOS, Problemy Nauk Biologicznych (rok: 2020, tom: 69, strony: 563–577), Wydawca: Polskie Towarzystwo Przyrodników im. Kopernika
    Status:
    Published
    DOI:
    brak - link to the publication

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