Projects funded by the NCN
Analysis of intracellular mechanisms regulating transgene expression from AAV vectors of various serotypes
2019/33/N/NZ1/03066
Keywords:
gene therapy AAV vectors transduction mechanism antiviral response DNA damage response human iPS cells cardiomyocytes fibroblasts
Descriptors:
- NZ1_001:
- NZ1_005:
- NZ6_005:
Panel:
NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution :
Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii
woj. małopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 17 - announced on 2019-03-15
Amount awarded: 209 874 PLN
Project start date (Y-m-d): 2020-02-20
Project end date (Y-m-d): 2024-02-19
Project duration:: 48 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- Casein kinase 2 activity is a host restriction factor for AAV transductionAuthors:Izabela Kraszewska, Katarzyna Sarad, Kalina Andrysiak, Aleksandra Kopacz, Luisa Schmidt, Marcus Krüger, Józef Dulak, Agnieszka Jaźwa-KusiorAcademic press:Molecular Therapy (rok: 2023, tom: 32, 1, strony: 84-102), Wydawca: Cell PressStatus:PublishedDOI:10.1016/j.ymthe.2023.11.010 - link to the publication