Search results

1. Structural basis of biological properties of muscle fructose-1,6-bisphosphatase (FBPase) - a regulatory enzyme of glycon…

Principal investigator: prof. Andrzej Dżugaj

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Call: OPUS 5, Panel: NZ1

2. Gene expression, protein concentration and enzymatic activity of redox enzymes in relation to trace element status in li…

Principal investigator: Jakub Piotr Adamus

Warszawski Uniwersytet Medyczny

Call: PRELUDIUM 24, Panel: NZ1

3. The use of proteolytic enzymes isolated form nonconventional sources for obtaining biologically active peptides from mil…

Principal investigator: dr Anna Ewa Dąbrowska

Uniwersytet Przyrodniczy we Wrocławiu, Wydział Nauk o Żywności

Call: OPUS 1, Panel: NZ9

4. Structural studies on inhibition mechanisms of enzymes belonging to USP family, which remove ubiquitin from eukaryotic p…

Principal investigator: dr Marcin Jarosław Ziemniak

Uniwersytet Warszawski, Wydział Chemii

Call: SONATINA 1, Panel: NZ1

5. Assessment of changes in mitochondria and the activity of selected enzymes and mitochondrial proteins in freshwater shri…

Principal investigator: Anna - Ostróżka

UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

Call: PRELUDIUM 20, Panel: NZ8

6. Exploring the mechanisms of therapy-facilitated metastasis and CAAX proteins-processing enzymes in liver cancer

Principal investigator: dr Jarosław Marek Cisowski

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: OPUS 19, Panel: NZ4

7. Comparative mRNA expression, protein abundance and regulatory mechanisms of drug metabolising eznymes and transporters i…

Principal investigator: prof. Marek Droździk

Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Lekarski z Oddziałem Nauczania w Języku Angielskim

Call: OPUS 9, Panel: NZ7

8. Application of PROTAC strategy for controlling Rab geranylgeranyl transferase and Rab proteins

Principal investigator: dr hab. Katarzyna Magdalena Błażewska

Politechnika Łódzka, Wydział Chemiczny

Call: PRELUDIUM BIS 2, Panel: ST4

9. NanoBioCat: Developing biopolymer-based and protein friendly ionic liquids assisted enzyme nano-constructs with improved…

Principal investigator: dr Dibyendu Mondal

Instytut Genetyki Roślin PAN

Call: SONATA 17, Panel: ST4

10. Structural study of the complexes of hydrolytic enzymes with heteroorganic substrates and substrate analogs

Principal investigator: dr hab. Jarosław Błaszczyk

Centrum Badań Molekularnych i Makromolekularnych PAN

Call: OPUS 3, Panel: ST4

11. Novel, rationally designed modulators of glycosomal import of enzymes in Trypanosoma parasites

Principal investigator: prof. Maciej Filip Dawidowski

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

Call: OPUS 16, Panel: NZ7

12. Novel L-asparaginases as potential therapeutic agents and antimicrobial targets: structural and functional studies of en…

Principal investigator: prof. Mariusz Jaskólski

Instytut Chemii Bioorganicznej PAN

Call: OPUS 19, Panel: NZ1

13. Designing mRNA transcripts resistant to enzymatic cap hydrolysis applicable for anti-cancer vaccines; multiplexed bioche…

Principal investigator: prof. Edward Darżynkiewicz

Uniwersytet Warszawski

Call: MAESTRO 4, Panel: NZ1

14. Design and synthesis of probes for RabGGTase profiling and their application for identification of the site of phosphono…

Principal investigator: dr hab. Katarzyna Błażewska

Politechnika Łódzka, Wydział Chemiczny

Call: SONATA BIS 4, Panel: ST5

15. Multi-domain proteins with disordered linkers in cellulose decomposition and cell adhesion

Principal investigator: dr Bartosz Jan Różycki

Instytut Fizyki PAN

Call: OPUS 11, Panel: NZ1

16. Mechanisms of cyclization reactions leading to biologically active compounds catalyzed by iron dependent enzymes.

Principal investigator: prof. Tomasz Maciej Borowski

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

Call: OPUS 23, Panel: ST4

17. Combined experimental and theoretical studies of the catalytic activity of RPE65 enzyme using biomimetic active centre m…

Principal investigator: dr hab. Adam Maciej Kubas

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Call: OPUS 20, Panel: ST4

18. Structure and function of anti-virulent phage origin enzymes active against ESKAPE pathogens

Principal investigator: prof. Zuzanna Drulis-Kawa

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Call: HARMONIA 9, Panel: NZ1

19. Cytoplasmic enzymes of pathogenic fungi Candida spp. that moonlight as adhesins on the cell wall - structural determinan…

Principal investigator: prof. Andrzej Kozik

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: OPUS 12, Panel: NZ6

20. Investigation of the molecular mechanisms of anti-leukemic activity of SK053, a small molecule compound targeting enzyme…

Principal investigator: prof. Dominika Anna Nowis

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: SONATA BIS 3, Panel: NZ5

21. Dual-function tail phage proteins- determination of the function and the mechanism of action towards (poly)saccharides

Principal investigator: dr Ewa Brzozowska

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Call: SONATA BIS 7, Panel: NZ1

22. Optimization of coarse-grained molecular dynamics simulations for tunnel exploration of large proteins with buried activ…

Principal investigator: Nishita Mandal

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: PRELUDIUM 22, Panel: NZ2

23. Characterization of hydrolysates and peptides derived from oat kernels proteins in the context of their activity in dise…

Principal investigator: dr Monika Anna Pliszka

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Nauki o Żywności

Call: PRELUDIUM 16, Panel: NZ9

24. 2-Oxoglutarate dependent oxygenases in the biosynthesis of pharmacologically active alkaloids - structure, catalytic mec…

Principal investigator: prof. Tomasz Maciej Borowski

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

Call: SONATA BIS 4, Panel: NZ1

25. Evaluating the antibacterial activity of the bacteriophage protein targeting Staphylococcus aureus, including drug-resis…

Principal investigator: dr Zuzanna Maria Kaźmierczak

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Call: SONATA 19, Panel: NZ7

26. Exposing unseen passages - towards identification of functional transient tunnels in protein structures

Principal investigator: dr hab. Jan Brezovský

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: PRELUDIUM BIS 5, Panel: NZ2

27. Dependence of growth of young pig from protein qualitative digestion - peptide vs. amino acid absorption

Principal investigator: Kamil Krzysztof Zaworski

Instytut Fizjologii i Żywienia Zwierząt im. Jana Kielanowskiego PAN

Call: PRELUDIUM 20, Panel: NZ9

28. Hybrid human SUMO proteins for selective detection and labelling of SENP proteases

Principal investigator: dr hab. Wioletta Katarzyna Rut-Schedlok

Politechnika Wrocławska

Call: OPUS 21, Panel: ST4

29. Chiroptical properties of proteins and their complexes (CRISPR/Cas-RNA), and their relationship to biological activity

Principal investigator: dr Monika Anna Hałat

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Biotechnologii i Ogrodnictwa

Call: SONATINA 5, Panel: ST4

30. Assessing protein-ligand complexes with ML/DL models trained on molecular dynamics-based descriptors.

Principal investigator: dr hab. Paweł Aleksander Siedlecki

Instytut Biochemii i Biofizyki PAN

Call: OPUS 20, Panel: ST4

31. Novel families of ADP-ribosyltransferases and proteins involved in ADP-ribosylation.

Principal investigator: dr hab. Krzysztof Piotr Pawłowski

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

Call: OPUS 17, Panel: NZ2

32. Development of method based on fluorescence polarization for high affinity ligand searching toward m7G nucleotide bindin…

Principal investigator: Anna Wojtczak

Uniwersytet Warszawski, Wydział Fizyki

Call: PRELUDIUM 11, Panel: ST4

33. De novo design of cavity-incorporating mini-proteins and their application in catalysis

Principal investigator: prof. Łukasz Berlicki

Politechnika Wrocławska

Call: OPUS 22, Panel: ST4

34. Comprehensive research on enzymatic hydrolysis of native and chemically modified 5' RNA structures by Nudix protein fami…

Principal investigator: prof. Edward Darżynkiewicz

Uniwersytet Warszawski, Wydział Fizyki

Call: OPUS 14, Panel: NZ1

35. In search of adaptive strategies in obligatory predators - The immunological mechanisms in reared model spider species S…

Principal investigator: dr hab. Grażyna Iwona Wilczek

UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

Call: OPUS 19, Panel: NZ8

36. Nanostructures in electrochemical biosensors and SERS indicators

Principal investigator: dr hab. Barbara Jadwiga Pałys

Uniwersytet Warszawski, Wydział Chemii

Call: OPUS 2, Panel: ST4

37. Light-induced photoreceptor morphological changes – Towards objective and impartial diagnostics in ophthalmology

Principal investigator: dr Humberto Couto Fernandes

Instytut Chemii Fizycznej Polskiej Akademii Nauk, Międzynarodowe Centrum Badań Oka

Call: OPUS 26, Panel: NZ7

38. New applications of non-conventional nonempirical methodologies for the analysis of catalytic and inhibitory properties …

Principal investigator: dr Edyta Dyguda-Kazimierowicz

Politechnika Wrocławska

Call: OPUS 25, Panel: ST4

39. Structural and functional characterization of loci determining the content of cell wall-bound phenolics under the condit…

Principal investigator: dr hab. Tomasz Hura

Instytut Fizjologii Roślin im. Franciszka Górskiego PAN

Call: OPUS 16, Panel: NZ9

40. A novel continuous method of proteolysis in hierarchically structured microreactor

Principal investigator: dr Katarzyna Szymańska

Politechnika Śląska, Wydział Chemiczny

Call: SONATA 5, Panel: ST8

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