Projects funded by the NCN

Parallel microevolution of metabolic plasticity and chemoresistance of cancer cells: a key to understanding cancer relap...

Call: OPUS 28 , Panel: NZ3

Principal investigator: prof. Jarosław Piotr Czyż

Uniwersytet Jagielloński

Exploiting the weakness of lymphoma: spectroscopic identification of biomarkers for lymphoma metabolism and inducing its...

Call: PRELUDIUM 23 , Panel: ST4

Principal investigator: Patrycja Dawiec

Uniwersytet Jagielloński

Design and Development of Serine Hydroxymethyltransferase-2 (SHMT2) Inhibitors Blocking Tumor Growth

Call: SONATA BIS 13 , Panel: NZ7

Principal investigator: dr hab. Miłosz Ruszkowski

Instytut Chemii Bioorganicznej PAN

Cuproptosis, a novel pathway of regulated cell death as a therapeutic target in treatment-naïve and targeted therapy-res...

Call: OPUS 25 , Panel: NZ5

Principal investigator: dr hab. Mariusz Łukasz Hartman

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Inhibiting the Mitochondrial Intermembrane Space Assembly pathway as a newapproach to prevent metabolic reprogramming of...

Call: OPUS 22 , Panel: NZ5

Principal investigator: dr hab. Carlo Vascotto

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Relationship between ATPase activity stimulation and transport - the case of selective Medicago truncatula ABCG transpor...

Call: PRELUDIUM 20 , Panel: NZ1

Principal investigator: dr Konrad Mateusz Pakuła

Instytut Chemii Bioorganicznej PAN

Structural insights into the involvement of the RNA degradosome in trans-translation in the light of the antimicrobial a...

Call: SONATA BIS 9 , Panel: NZ1

Principal investigator: dr Przemysław Adam Płociński

Uniwersytet Łódzki

Specific interactions of new antitumor unsymmetrical bisacridines, UAs, with DNA and ABC proteins and their potential to...

Call: OPUS 17 , Panel: NZ7

Principal investigator: prof. Zofia Mazerska

Politechnika Gdańska

The enzymes of RNA metabolism, PAP I and PNPase, as targets for new antimycobacterial drugs and their functional charact...

Call: OPUS 13 , Panel: NZ7

Principal investigator: prof. Jarosław Dziadek

Instytut Biologii Medycznej PAN

Study on metabolism of microorganisms treated with metal nanoparticles, antibiotics, metal ions and their combinations u...

Call: PRELUDIUM 13 , Panel: ST4

Principal investigator: Agnieszka Maria Rogowska

Uniwersytet Mikołaja Kopernika, Wydział Chemii

CBR1-dependent metabolism and ABCB1-dependent effux of doxorubicin - search for a novel mechanism of reversing resistanc...

Call: PRELUDIUM 13 , Panel: NZ7

Principal investigator: Kamil Tomasz Piska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Hyphenated separation techniques in the study of the molecular mechanisms of metabolic biotransformation of drugs for ta...

Call: SONATA 12 , Panel: ST4

Principal investigator: dr Małgorzata Szultka-Młyńska

Uniwersytet Mikołaja Kopernika, Wydział Chemii

Porphyrazine based catalyst support for biomimetic studies on selected active pharmaceutical ingredients

Call: PRELUDIUM 9 , Panel: NZ7

Principal investigator: Tomasz Władysław Koczorowski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

The impact of P450 and UGT isoenzyme overexpression on cellular response induced by antitumor acridinone derivatives. Th...

Call: OPUS 5 , Panel: NZ3

Principal investigator: prof. Zofia Mazerska

Politechnika Gdańska, Wydział Chemiczny

Evaluation of influence of genetic factors associated with transport and metabolizm of immunosuppressive agents on blood...

Call: OPUS 5 , Panel: NZ2

Principal investigator: prof. Leszek Pączek

Warszawski Uniwersytet Medyczny, I Wydział Lekarski

Genetic background of aminoglycoside-induced hearing loss - mitochondrial and nuclear genes involvement

Call: SONATA 5 , Panel: NZ5

Principal investigator: dr Małgorzata Aleksandra Rydzanicz

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Novel, chemometrically assisted, metabolic based research strategy in anticancer drug development on the example of benz...

Call: PRELUDIUM 1 , Panel: NZ1

Principal investigator: Mariusz Marcin Belka

Gdański Uniwersytet Medyczny, Wydział Faramcautyczny z Oddziałem Medycyny Laboratoryjnej