Influence of prenylflavonoids from hops (Humulus lupulus L)o n hipogonadism-induced disturbances in thermoregulation and bone tissue metabolism, structure and biomechanical properties.
2016/21/B/NZ7/02759
Keywords
Descriptors
- NZ7_14: Farmacja, farmakoterapia, farmakologia
- ST5_1: Właściwości strukturalne materiałów
- NZ9_7: Naukowe podstawy żywienia i badania żywności
Panel
NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution
Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej, Wydział Lekarski
Voivodeship: dolnośląskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 14
Call
OPUS 11 – announced on 2016-03-15
- Amount awarded
- 719 100 PLN
- Project start date
- 2017-05-16
- Project end date
- 2020-05-15
- Project duration
- 36 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- Zestaw do telemetrycznego pomiaru temperatury. Cost: 50 000 PLN
- dyski zewnętrzne 6 TB i 8 TB. Cost: 1 258 PLN
- membranowa pompa próżniowa przyspieszająca odparowywanie i produkcje ekstraktów. Cost: 27 000 PLN
- wgłębnik do mikrotwardosciomierza. Cost: 9 000 PLN
Information in the final report
Publication in academic press/journals (4)
-
Synthesis and antiproliferative activity of minor hops prenylflavonoids and new insight on prenyl group cyclization
- Authors:
- Jarosław Popłoński, Eliza Turlej, Sandra Sordon, Tomasz Tronina, Agnieszka Bartmańska, Joanna Wietrzyk, Ewa Huszcza
- Academic press:
- Molecules (year: 2018, volume: 23, pages: 776), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/molecules23040776 – link to the publication
-
Simple and green method for the extraction of xanthohumol from spent hops using deep eutectic solvents
- Authors:
- Aleksandra Grudniewska, Jarosław Popłoński
- Academic press:
- Separation and Purification Technology (year: 2020, volume: 250, pages: 117196), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.seppur.2020.117196 – link to the publication
-
Pharmacokinetics of xanthohumol in rats of both sexes after oral and intravenous administration of pure xanthohumol and prenylflavonoid extract.
- Authors:
- Beata Nowak, Błażej Poźniak, Jarosław Popłoński, Łukasz Bobak, Agnieszka Matuszewska, Joanna Kwiatkowska, Wojciech Dziewiszek, Ewa Huszcza, Adam Szeląg
- Academic press:
- Advances in Clinical and Experimental Medicine (year: 2020, volume: 29 (9), pages: 1101-1109), Publisher: Wroclaw Medical University
- Status:
- Published
- DOI:
- 10.17219/acem/126293 – link to the publication
-
Prenylflavonoids counteract ovariectomy-induced disturbances in rats
- Authors:
- Beata Nowak, Agnieszka Matuszewska, Jarosław Popłoński, Anna Nikodem, Jarosław Filipiak, Magdalena Tomanik, Wojciech Dziewiszek, Maciej Danielewski, Kinga Belowska-Bień, Marek Kłobucki, Sandra Sordon, Diana Jędrzejuk, Ireneusz Ceremuga, Małgorzata Trocha, Tomasz Sozański, Tomasz Piasecki, Marek Bolanowski, Ewa Huszcza, and Adam Szeląg
- Academic press:
- Journal of Functional Foods (year: 2021, volume: 86, pages: 104742), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.jff.2021.104742 – link to the publication
Articles in post-conference publications (1)
-
Effect of mangiferin therapy on structural and mechanical properties of trabecular bone tissue in L4 vertebral rats
- Authors:
- Anna Nikodem, Beata Nowak, Agnieszka Matuszewska, Jarosław Filipiak
- Conference:
- Biomechanics 2018 : International Conference of the Polish Society of Biomechanics (year: 2018, pages: s.159-160), Publisher: Uniwersytet Zielonogórski, Wydział Mechaniczny, Zakład Inżynierii Biomedycznej
- Date:
- conference 5-7. 09.2018
- Status:
- Published