Solid phase microextraction-based universal analytical platform for assessment of in vitro generated metabolism
2016/23/N/NZ7/01929
Keywords
Descriptors
- NZ7_14: Farmacja, farmakoterapia, farmakologia
Panel
NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution
Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy; Wydział Farmaceutyczny
Voivodeship: kujawsko-pomorskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 2
Call
PRELUDIUM 12 – announced on 2016-09-15
- Amount awarded
- 150 000 PLN
- Project start date
- 2017-07-13
- Project end date
- 2020-07-12
- Project duration
- 36 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- Drukarka 3D. Cost: 5 000 PLN
- Rotor do wirówki odpowiedni do wirowania płytek 96-dołkowych. Cost: 7 000 PLN
- Statyw do autosamplera Thermo Q-Exactive Orbitrap przystosowany do płytek 96-dołkowych (2 pcs). Cost: 2 400 PLN
- Wirówka laboratoryjna wraz z rotorem na płytki 2 x 96-dołkowa.
- kontener do przechowywania próbek w ciekłym azocie typu "Dewar" YDS-20.
Information in the final report
Publication in academic press/journals (1)
-
Untargeted screening of phase I metabolism of combretastatin A4 by multitool analysis
- Authors:
- Karol Jaroch, Paulina Zofia Goryńska, Krzysztof Goryński, Tomasz Stefański, Barbara Bojko
- Academic press:
- Talanta (year: 2018, volume: 182, pages: 22–31), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.talanta.2018.01.051 – link to the publication
Articles in post-conference publications (1)
-
UNREVEALING PHASE I METABOLISM OF COMBRETASTATIN A4 BY A MULTI-TOOL MS-BASED APPROACH
- Authors:
- Karol Jaroch, Paulina Zofia Goryńska, Krzysztof Goryński, Tomasz Stefański, Barbara Bojko
- Conference:
- INTERNATIONAL MASS SPECTROMETRY CONFERENCE (IMSC) 2018 (year: 2018, pages: 522-523), Publisher: Societa Chimica Italiana, International Mass Spectrometry Foundation
- Date:
- conference 26-31.08
- Status:
- Published