Projects funded by the NCN

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Evaluation of the role of estrogen receptors in the effect of mycotoxin zearalenone on cell metabolism, oxidative stress and invasiveness of prostate proper and cancer cells.

2016/23/N/NZ7/02510

Keywords:

zearalenone mycotoxin prostate cancer estrogens

Descriptors:

  • NZ7_2: Environment and health risks
  • NZ7_12: Prevention of human diseases
  • NZ7_15: Toxicology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Nauk Biomedycznych i Kształcenia Podyplomowego

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Karolina Kowalska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 12 - announced on 2016-09-15

Amount awarded: 99 900 PLN

Project start date (Y-m-d): 2017-09-21

Project end date (Y-m-d): 2019-09-20

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  1. Estrogen Receptor α Is Crucial in Zearalenone-Induced Invasion and Migration of Prostate Cancer Cells.
    Authors:
    Kowalska K, Habrowska-Górczyńska DE, Urbanek KA, Domińska K, Piastowska-Ciesielska AW.
    Academic press:
    Toxins (Basel) (rok: 2018, tom: 10(3), strony: pii: E98), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/toxins10030098 - link to the publication
  2. Estrogen receptor β plays a protective role in zearalenone-induced oxidative stress in normal prostate epithelial cells.
    Authors:
    Kowalska K, Habrowska-Górczyńska DE, Urbanek KA, Domińska K, Sakowicz A, Piastowska-Ciesielska AW.
    Academic press:
    Ecotoxicology and Environmental Safety (rok: 2019, tom: 172, strony: 504-513), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.ecoenv.2019.01.115 - link to the publication

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