Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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In search of antiplatelet mechamism of CORMs (CO-releasing molecules): significance of kinetic of CO release, antiadhesive effect and influence on platelet metabolism.

2016/21/N/NZ7/02524

Keywords:

blood platelets CO adhesion metabolism

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Barbara Sitek 

Number of co-investigators in the project: 2

Call: PRELUDIUM 11 - announced on 2016-03-15

Amount awarded: 100 000 PLN

Project start date (Y-m-d): 2017-02-17

Project end date (Y-m-d): 2019-02-16

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Spin coater (10 000 PLN)

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (1)
  1. Antiplatelet Effect of Carbon Monoxide Is Mediated by NAD+ and ATP Depletion
    Authors:
    Patrycja Kaczara, Barbara Sitek, Kamil Przyborowski, Anna Kurpińska, Kamil Kuś, Marta Stojak,Stefan Chłopicki.
    Academic press:
    Arteriosclerosis, Thrombosis, and Vascular Biology (rok: 2020, tom: 40, strony: 2376–2390), Wydawca: Lippincott Williams & Wilkins (LWW)
    Status:
    Published
    DOI:
    10.1161/ATVBAHA.120.314284 - link to the publication
  1. Searching of mechanism of anti-aggregatory activity of CORM-A1, based on its effect on the metabolism of platelets.
    Authors:
    Barbara Sitek, Patrycja Kaczara, Stefan Chłopicki
    Conference:
    25th Kraków Conference on Endothelium, 2017 (rok: 2017, ), Wydawca: JCET
    Data:
    konferencja 20-21. 10. 2017
    Status:
    Published