The role of PIM kinases in the vascular niche of multiple myeloma
2018/31/N/NZ5/03214
Keywords
Descriptors
- NZ5_3: Patogeneza chorób człowieka
- NZ5_7: Leczenie chorób człowieka
Panel
NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution
Instytut Hematologii i Transfuzjologii
Voivodeship: mazowieckie
Principal investigator (from the host institution)
Number of co-investigators in the project: 2
Call
PRELUDIUM 16 – announced on 2018-09-14
- Amount awarded
- 210 000 PLN
- Project start date
- 2019-07-22
- Project end date
- 2023-07-21
- Project duration
- 48 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (1)
-
Characterization and Experimental Use of Multiple Myeloma Bone Marrow Endothelial Cells and Progenitors
- Authors:
- Filip Garbicz, Marcin Kaszkowiak, Julia Dudkiewicz-Garbicz, David M. Dorfman, Julia Ostrowska, Joanna Barankiewicz, Aleksander Salomon-Perzyński, Ewa Lech-Marańda, Tuyet Nguyen, Przemyslaw Juszczyński, Ruben D. Carrasco, Irena Misiewicz-Krzeminska
- Academic press:
- International Journal Molecular Science (year: 2024, volume: 25, pages: 12047), Publisher: Multidisciplinary Digital Publishing Institute
- Status:
- Published
- DOI:
- 10.3390/ijms252212047 – link to the publication
Articles in post-conference publications (3)
-
Hodgkin Lymphoma Reed-Sternberg Cells Induce Immunosuppressive and Pro-Angiogenic Phenotype of Tumor-Associated Macrophages in a Paracrine Manner
- Authors:
- Maciej Szydlowski, Michał Pawlak, Filip Garbicz, Patryk Górniak, Justyna Żurańska, Magdalena Król, Bartłomiej Taciak, Maciej Białasek, Anna Szumera-Ciećkiewicz, Kamil Sokół, Monika Stańczak, Daria Owczarek, Monika Prochorec-Sobieszek, MD, Anna Polak, PhD, Emilia Bialopiotrowicz, PhD, Michał Kurlapski, Jan Zaucha, Paweł Wołkow, and Przemyslaw Juszczynski
- Conference:
- 62nd ASH Annual Meeting and Exposition (year: 2020, pages: 136 (Supplement 1): 30), Publisher: American Society of Hematology
- Date:
- conference 5-8.12
- Status:
- Published
-
Super-Enhancer-Driven PIM Kinase Upregulation in Multiple Myeloma Maintains the Plasma Cell-Specific Oncogenic and Microenvironmental Circuits, and Can be Efficiently Targeted By the Pan-PIM Inhibitor MEN1703
- Authors:
- Filip Garbicz, Sonia Debek, Anna Szumera-Ciećkiewicz, Joanna Barankiewicz, Dorota Komar, Michał Pawlak, Aleksandra Matrejek, Thorsten Stuehmer, Aleksander Salomon-Perzynski, Agata Malenda, Julia Ostrowska, Julia Dudkiewicz, Krzysztof Brzózka, Tomasz Rzymski, Daniela Bellarosa, Ewa Lech-Marańda, Monika Prochorec-Sobieszek, Zofia Pilch, Dominika Nowis, Jakub Golab, Helen Tanton, Teru Hideshima, David M. Dorfman, Irena Misiewicz-Krzeminska, Tomasz Sewastianik, Ruben D. Carrasco, Maciej Szydlowski, Przemyslaw Juszczynski
- Conference:
- 63rd ASH Annual Meeting and Exposition (year: 2022, pages: 140 (Supplement 1): 4189–4190.), Publisher: American Society of Hematology
- Date:
- conference 11-14.12
- Status:
- Published
-
PIM Kinase Inhibition Decreases the Proangiogenic Properties of Multiple Myeloma Cells and Affects the Metabolic State of the Vascular Endothelium
- Authors:
- Filip Garbicz, Anna Szumera-Ciećkiewicz, Joanna Barankiewicz, Dorota Komar, Michał Pawlak, Sonia Dębek, Aleksandra Matrejek, Thorsten Stuehmer, Aleksander Salomon-Perzynski, Agata Malenda, Krzysztof Brzózka, Tomasz Rzymski, Andrea Massimiliano Tomirotti, Ewa Lech-Marańda, Monika Prochorec-Sobieszek, Maciej Szydlowski and Przemyslaw Juszczynski
- Conference:
- 62nd ASH Annual Meeting and Exposition (year: 2020, pages: Blood (2020) 136 (Supplement 1): 16–17.), Publisher: American Society of Hematology
- Date:
- conference 5-8.12
- Status:
- Published