Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

The role of PIM kinases in the vascular niche of multiple myeloma

2018/31/N/NZ5/03214

Keywords:

PIM kinases multiple myeloma angiogenesis microenvironment

Descriptors:

  • NZ5_3:
  • NZ5_7:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Hematologii i Transfuzjologii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Filip Aleksander Garbicz 

Number of co-investigators in the project: 2

Call: PRELUDIUM 16 - announced on 2018-09-14

Amount awarded: 210 000 PLN

Project start date (Y-m-d): 2019-07-22

Project end date (Y-m-d): 2023-07-21

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (3)
  1. Characterization and Experimental Use of Multiple Myeloma Bone Marrow Endothelial Cells and Progenitors
    Authors:
    Filip Garbicz, Marcin Kaszkowiak, Julia Dudkiewicz-Garbicz, David M. Dorfman, Julia Ostrowska, Joanna Barankiewicz, Aleksander Salomon-Perzyński, Ewa Lech-Marańda, Tuyet Nguyen, Przemyslaw Juszczyński, Ruben D. Carrasco, Irena Misiewicz-Krzeminska
    Academic press:
    International Journal Molecular Science (rok: 2024, tom: 25, strony: 12047), Wydawca: Multidisciplinary Digital Publishing Institute
    Status:
    Published
    DOI:
    10.3390/ijms252212047 - link to the publication
  1. Super-Enhancer-Driven PIM Kinase Upregulation in Multiple Myeloma Maintains the Plasma Cell-Specific Oncogenic and Microenvironmental Circuits, and Can be Efficiently Targeted By the Pan-PIM Inhibitor MEN1703
    Authors:
    Filip Garbicz, Sonia Debek, Anna Szumera-Ciećkiewicz, Joanna Barankiewicz, Dorota Komar, Michał Pawlak, Aleksandra Matrejek, Thorsten Stuehmer, Aleksander Salomon-Perzynski, Agata Malenda, Julia Ostrowska, Julia Dudkiewicz, Krzysztof Brzózka, Tomasz Rzymski, Daniela Bellarosa, Ewa Lech-Marańda, Monika Prochorec-Sobieszek, Zofia Pilch, Dominika Nowis, Jakub Golab, Helen Tanton, Teru Hideshima, David M. Dorfman, Irena Misiewicz-Krzeminska, Tomasz Sewastianik, Ruben D. Carrasco, Maciej Szydlowski, Przemyslaw Juszczynski
    Conference:
    63rd ASH Annual Meeting and Exposition (rok: 2022, ), Wydawca: American Society of Hematology
    Data:
    konferencja 11-14.12
    Status:
    Published
  2. PIM Kinase Inhibition Decreases the Proangiogenic Properties of Multiple Myeloma Cells and Affects the Metabolic State of the Vascular Endothelium
    Authors:
    Filip Garbicz, Anna Szumera-Ciećkiewicz, Joanna Barankiewicz, Dorota Komar, Michał Pawlak, Sonia Dębek, Aleksandra Matrejek, Thorsten Stuehmer, Aleksander Salomon-Perzynski, Agata Malenda, Krzysztof Brzózka, Tomasz Rzymski, Andrea Massimiliano Tomirotti, Ewa Lech-Marańda, Monika Prochorec-Sobieszek, Maciej Szydlowski and Przemyslaw Juszczynski
    Conference:
    62nd ASH Annual Meeting and Exposition (rok: 2020, ), Wydawca: American Society of Hematology
    Data:
    konferencja 5-8.12
    Status:
    Published
  3. Hodgkin Lymphoma Reed-Sternberg Cells Induce Immunosuppressive and Pro-Angiogenic Phenotype of Tumor-Associated Macrophages in a Paracrine Manner
    Authors:
    Maciej Szydlowski, Michał Pawlak, Filip Garbicz, Patryk Górniak, Justyna Żurańska, Magdalena Król, Bartłomiej Taciak, Maciej Białasek, Anna Szumera-Ciećkiewicz, Kamil Sokół, Monika Stańczak, Daria Owczarek, Monika Prochorec-Sobieszek, MD, Anna Polak, PhD, Emilia Bialopiotrowicz, PhD, Michał Kurlapski, Jan Zaucha, Paweł Wołkow, and Przemyslaw Juszczynski
    Conference:
    62nd ASH Annual Meeting and Exposition (rok: 2020, ), Wydawca: American Society of Hematology
    Data:
    konferencja 5-8.12
    Status:
    Published

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy