Projects funded by the NCN
Iron chelators as tyrosine kinase inhibitors - a new strategy for the treatment of glioblastoma multiforme
2020/39/O/NZ5/02342
Keywords:
glioblastoma multiforme iron chelator tyrosine kinase inhibitor blood-brain barrier
Descriptors:
- NZ5_007:
- NZ3_005:
- NZ7_014:
Panel:
NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution :
UNIWERSYTET ŚLĄSKI, Wydział Nauk Ścisłych i Technicznych
woj. śląskie
Principal investigator (from the host institution):
dr hab. Anna Dominika Mrozek-Wilczkiewicz
Number of co-investigators in the project: 2
Call: PRELUDIUM BIS 2 - announced on 2020-09-15
Amount awarded: 541 680 PLN
Project start date (Y-m-d): 2021-10-01
Project end date (Y-m-d): 2025-09-30
Project duration:: 48 months (the same as in the proposal)
Project status: Project completed
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (3)
- 4-Furanylvinylquinoline derivative as a new scaffold for the design of oxidative stress initiator and glucose transporter inhibitor drugsAuthors:M. Kuczak, W. Cieślik, R. Musioł, A. Mrozek-WilczkiewiczAcademic press:Scientific Reports (rok: 2024, tom: 14, strony: 28454), Wydawca: Nature PortfolioStatus:PublishedDOI:10.1038/s41598-024-79698-0 - link to the publication
- Iron Metabolism in Aminolevulinic Acid-Photodynamic Therapy with Iron Chelators from the Thiosemicarbazone GroupAuthors:R. Gawecki, P. Rawicka, M. Rogalska, M. Serda, A. Mrozek-WilczkiewiczAcademic press:International Journal of Molecular Sciences (rok: 2024, tom: 25(19), strony: 10468), Wydawca: MDPIStatus:PublishedDOI:10.3390/ijms251910468 - link to the publication
- Imbalance of redox homeostasis and altered cellular signaling induced by the metal complexes of terpyridineAuthors:Malarz K., Ziola P., Zych D., Rurka P., Mrozek-Wilczkiewicz A.Academic press:Scientific Reports (rok: 2024, tom: 14, strony: 26951), Wydawca: Nature PortfolioStatus:PublishedDOI:10.1038/s41598-024-77575-4 - link to the publication