Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Significance of PIM-1 kinase mutations in progression of chronic lymphocytic leukemia

2016/21/D/NZ5/02569

Keywords:

oncogenesis kinases biomarkers targeted therapies

Descriptors:

  • NZ5_3: Pathogenesis of human diseases
  • NZ5_5: Diagnostics in human diseases
  • NZ5_7: Human disease treatment

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Hematologii i Transfuzjologii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Bartosz Puła 

Number of co-investigators in the project: 3

Call: SONATA 11 - announced on 2016-03-15

Amount awarded: 996 750 PLN

Project start date (Y-m-d): 2017-03-20

Project end date (Y-m-d): 2020-06-19

Project duration:: 39 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Notebook (5 500 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  1. Comparable Efficacy of Idelalisib Plus Rituximab and Ibrutinib in Relapsed/refractory Chronic Lymphocytic Leukemia: A Retrospective Case Matched Study of the Polish Adult Leukemia Group (PALG).
    Authors:
    Puła B, Budziszewska BK, Rybka J, Gil L, Subocz E, Długosz-Danecka M, Zawirska D, Waszczuk-Gajda A, Iskierka-Jażdżewska E, Kopacz A, Szymczyk A, Czyż J, Lech-Marańda E, Warzocha K, Jamroziak K.
    Academic press:
    Anticancer Res. (rok: 2018, tom: 38, strony: 3025-3030), Wydawca: The International Institute of Anticancer Research
    Status:
    Published
    DOI:
    10.21873/anticanres.12557 - link to the publication
  2. Immunochemotherapy for Richter syndrome: current insights.
    Authors:
    Puła B, Salomon-Perzyński A, Prochorec-Sobieszek M, Jamroziak K.
    Academic press:
    Immunotargets Ther. (rok: 2019, tom: 8, strony: 45305), Wydawca: Dove Press
    Status:
    Published
    DOI:
    10.2147/ITT.S167456 - link to the publication
  3. Overcoming Ibrutinib Resistance in Chronic Lymphocytic Leukemia
    Authors:
    Puła B, Gołos A, Górniak P, Jamroziak K.
    Academic press:
    Cancers (rok: 2019, tom: 11, strony: E1834), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers11121834 - link to the publication
  4. Efficacy of high-dose corticosteroid-based treatment for chronic lymphocytic leukemia patients with p53 abnormalities in the era of B-cell receptor inhibitors
    Authors:
    Puła B, Długosz-Danecka M, Salomon-Perzyński A, Szymczyk A, Subocz E, Budziszewska BK, Rybka J, Gil L, Waszczuk-Gajda A, Iskierka-Jażdżewska E, Zaucha JM, Osowiecki M, Piszczek W, Steckiewicz P, Szukalski Ł, Hus M, Lech-Marańda E, Jurczak W, Jamroziak K.
    Academic press:
    Advances in Medical Sciences (rok: 2020, tom: 65, strony: 371-377), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.advms.2020.06.002 - link to the publication
  5. Predictive significance of selected gene mutations in relapsed and refractory chronic lymphocytic leukemia patients treated with ibrutinib
    Authors:
    Machnicki MM, Górniak P, Pępek M, Szymczyk A, Iskierka-Jażdżewska E, Steckiewicz P, Bluszcz A, Rydzanicz M, Hus M, Płoski R, Makuch-Łasica H, Nowak G, Juszczyński P, Jamroziak K, Stokłosa T, Puła B
    Academic press:
    European Journal of Hematology (rok: 2021, tom: 106, strony: 320-326), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/ejh.13550 - link to the publication

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