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Information on the principal investigator and host institution

Information of the project and the call

Keywords

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The impact of S6K1 and S6K2 kinases on the efficiency of lysosomal degradation of cellular structures

2012/05/N/NZ3/00338

Keywords:

autophagy S6K1 kinase S6K2 kinase autophagosomes maturation lysosomes lipid droplets

Descriptors:

  • NZ3_1: Cell biology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Gdański, Wydział Biologii

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Aleksandra Hać 

Number of co-investigators in the project: 2

Call: PRELUDIUM 3 - announced on 2012-03-15

Amount awarded: 149 600 PLN

Project start date (Y-m-d): 2013-02-28

Project end date (Y-m-d): 2016-12-27

Project duration:: 46 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Kołyska laboratoryjna (3 500 PLN)
  2. Wytrząsarka do probówek o ruchu drgającym (795 PLN)
  3. Cytowirówka wraz z osprzętem (26 500 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (2)
  1. S6K1 controls autophagosome maturation in autophagy induced by sulforaphane or serum deprivation
    Authors:
    Aleksandra Hać, Anna Domachowska, Magdalena Narajczyk, Karolina Cyske, Anna Pawlika, Anna Herman-Antosiewicz
    Academic press:
    European Journal of Cell Biology (rok: 2015, tom: 94, strony: 470 – 481), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ejcb.2015.05.001 - link to the publication
  2. Lack of S6K1 in stress conditions affects microtubules acetylation leading to impaired autophagosomes-lysosomes fusion and autophagy flux
    Authors:
    Aleksandra Hać, Karolina Pierzynowska, Anna Pawlik, Anna Herman-Antosiewicz
    Academic press:
    Autophagy (rok: 2018, tom: nie dotyczy, strony: nie dotyczy), Wydawca: Taylor & Francis
    Status:
    Submitted
    DOI:
    brak - link to the publication
  1. Functions of lysosomes are impaired during prolonged stress conditions in cells devoid of S6K1/2
    Authors:
    Aleksandra Hać, Karolina Pierzynowska, Anna Herman-Antosiewicz
    Conference:
    13th Annual WORLDSymposium (rok: 2017, ), Wydawca: Elsevier Inc.
    Data:
    konferencja 13-17.02.2017 r.
    Status:
    Published
    DOI:
    link to the publication
  2. The impact of S6 kinases on autophagosomes maturation during the process of autophagy induced by sulforaphane, a chemopreventive and anticancer agent
    Authors:
    Karolina Pierzynowska1, Aleksandra Hać1, Anna Herman-Antosiewicz (1 These authors contributed equally to this work)
    Conference:
    Conference The Frontiers in Cancer Prevention : Fulfilled Promises, Translational Challenges and Future Directions (rok: 2015, ), Wydawca: Polskie Towarzystwo Biochemiczne i Komitet Biochemii i Biofizyki PAN
    Data:
    konferencja 24-27 czerwca 2015 r.
    Status:
    Published

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