Projects funded by the NCN

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51 projects found matching your search criteria :

  1. PAI-1 as a regulator of pro- and anti - apoptotic balance in endothelial cells

    Call: OPUS 1 , Panel: NZ3

    Principal investigator: dr hab. Joanna Boncela

    Instytut Biologii Medycznej PAN

  2. Early molecular mechanisms in invasive colon cancer cells induced by Snail controlled genes

    Call: MAESTRO 1 , Panel: NZ3

    Principal investigator: prof. Maria Anna Kowalska

    Instytut Biologii Medycznej PAN

  3. Identification of genes and epigenetic events involved in human Th17 differentiation.

    Call: SONATA BIS 5 , Panel: NZ5

    Principal investigator: dr Marcin Marek Ratajewski

    Instytut Biologii Medycznej PAN

  4. Vitamin B12 and mycobacterial persistence.

    Call: SONATA 10 , Panel: NZ6

    Principal investigator: dr Alina Ewa Minias

    Instytut Biologii Medycznej PAN

  5. Deciphering the role of putative protein factors involved in the mycobacterial DNA strand break repairs

    Call: OPUS 17 , Panel: NZ1

    Principal investigator: dr Przemysław Adam Płociński

    Instytut Biologii Medycznej PAN

  6. Influence of glycosylation of the SARS-CoV-2 Spike protein oncomplement activation

    Call: OPUS 20 , Panel: NZ6

    Principal investigator: dr hab. Maciej Cedzyński

    Instytut Biologii Medycznej PAN

  7. Implication of orphan response regulatory proteins in the physiology and virulence of Mycobacterium tuberculosis.

    Call: SONATA 6 , Panel: NZ6

    Principal investigator: dr Renata Anna Płocińska

    Instytut Biologii Medycznej PAN

  8. The mechanism and consequences of Ficolin-3 interaction with human cancer cells

    Call: PRELUDIUM 7 , Panel: NZ5

    Principal investigator: Mateusz Kazimierz Michalski

    Instytut Biologii Medycznej PAN

  9. How platelet microparticles affect invasiveness of colon cancer cells in the process of metastasis. Can we change it?

    Call: OPUS 15 , Panel: NZ5

    Principal investigator: prof. Maria Anna Kowalska

    Instytut Biologii Medycznej PAN

  10. Novel type modulators of purinergic receptors - Synthesis and study of receptor-ligand interaction

    Call: OPUS 7 , Panel: NZ1

    Principal investigator: prof. Zbigniew Jan Leśnikowski

    Instytut Biologii Medycznej PAN

  11. MOLECULES BINDING DNA - SYNTHESIS AND PROPERTIES OF DNA INTERCALATORS CONTAINING BORON CLUSTERS.

    Call: SONATA BIS 4 , Panel: ST5

    Principal investigator: dr hab. Agnieszka Bogusława Olejniczak

    Instytut Biologii Medycznej PAN

  12. Involvement of cholesterol oxidase of Mycobacterium tuberculosis in the modulation of TLR2-dependent signaling pathway i...

    Call: OPUS 8 , Panel: NZ6

    Principal investigator: dr hab. Magdalena Teresa Klink

    Instytut Biologii Medycznej PAN

  13. Collectin-liver 1 (CL-L1) and collectin-kidney 1 (CL-K1) in the susceptibilityof preterm neonates to infections

    Call: PRELUDIUM 19 , Panel: NZ6

    Principal investigator: dr Gabriela Katarzyna Gajek

    Instytut Biologii Medycznej PAN

  14. Novel mechanisms of immunomodulation by flame retardants

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: dr hab. Łukasz Pułaski

    Instytut Biologii Medycznej PAN

  15. Directed screening and evaluation of novel bactericidal compounds active againsttubercle bacilli and Mycobacterium absce...

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: prof. Jarosław Dziadek

    Instytut Biologii Medycznej PAN

  16. The evaluation of SNAIL 1 and SNAIL 2 transcriptional factors' role in the development of ovarian cancer cells' chemores...

    Call: SONATA 15 , Panel: NZ5

    Principal investigator: dr Michał Szymon Kiełbik

    Instytut Biologii Medycznej PAN

  17. Identification of the acetyl coenzyme A carboxylation mechanism i pathogenic and nonpathogenic mycobacterial species

    Call: PRELUDIUM 3 , Panel: NZ2

    Principal investigator: dr Jakub Pawełczyk

    Instytut Biologii Medycznej PAN

  18. Modulation the blood-brain barrier function, by nanoparticles - the environmental risk factors and nanotherapeutics.

    Call: OPUS 4 , Panel: NZ4

    Principal investigator: dr Katarzyna Dominika Kania

    Instytut Biologii Medycznej PAN

  19. Mycobacterium species and strains with varying cell wall composition: role of pattern recognition receptors in activatio...

    Call: PRELUDIUM 6 , Panel: NZ6

    Principal investigator: Iwona Karwaciak

    Instytut Biologii Medycznej PAN

  20. RecA independent response of tubercle bacilli to DNA damage

    Call: OPUS 10 , Panel: NZ6

    Principal investigator: dr hab. Anna Brzostek

    Instytut Biologii Medycznej PAN

  21. The role of core RNA decay machinery in regulation of metabolism of Mycobacterium tuberculosis

    Call: SONATA 10 , Panel: NZ1

    Principal investigator: dr Przemysław Adam Płociński

    Instytut Biologii Medycznej PAN

  22. Studies of the molecular mechanisms associated with HPV and CMV infections involved in the pathogenesis of ovarian cance...

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: dr hab. Edyta Teresa Paradowska

    Instytut Biologii Medycznej PAN

  23. Make an old drug great again – isoniazid/rifamycin-boron clusters conjugates – synthesis and antitubercular activity....

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Bogusława Olejniczak

    Instytut Biologii Medycznej PAN

  24. Functionalized carbohydrates pharmacophores as a putative antituberculosis drugs - the mechanism of action.

    Call: OPUS 8 , Panel: NZ7

    Principal investigator: prof. Jarosław Dziadek

    Instytut Biologii Medycznej PAN

  25. Badanie oddziaływania fikoliny H z lipopolisacharydami bakteryjnymi i efekty biologiczne tych interakcji

    Call: ETIUDA 3 , Panel: NZ6

    Principal investigator: Mateusz Kazimierz Michalski

    Instytut Biologii Medycznej PAN

  26. Investigation of the role of ficolins in anti-microbial defense in patients suffering from acute myeloid leukaemia, unde...

    Call: PRELUDIUM 4 , Panel: NZ6

    Principal investigator: Anna Katarzyna Sokołowska

    Instytut Biologii Medycznej PAN

  27. Composites of nucleic acids and oligofunctionalized boron clusters as new material for bionanotechnology

    Call: SYMFONIA 3 , Panel: ST5

    Principal investigator: prof. Zbigniew Jan Leśnikowski

    Instytut Biologii Medycznej PAN

  28. Role of sirtuin 2 (SIRT2) in the drug resistance of melanomas.

    Call: OPUS 9 , Panel: NZ5

    Principal investigator: dr Marcin Marek Ratajewski

    Instytut Biologii Medycznej PAN

  29. RIG-I-like receptors and human cytomegalovirus infection in the placenta: too much of good things?

    Call: PRELUDIUM 9 , Panel: NZ6

    Principal investigator: Agnieszka Beata Jabłońska

    Instytut Biologii Medycznej PAN

  30. Look at the mechanism of ovarian cancer cells response to adenine nucleosides modified with metallacarborane clusters wi...

    Call: OPUS 9 , Panel: NZ3

    Principal investigator: dr Katarzyna Bednarska

    Instytut Biologii Medycznej PAN

  31. Endocytosis-stimulating antibodies against multidrug transporters as drug carriers

    Call: OPUS 10 , Panel: NZ7

    Principal investigator: dr hab. Łukasz Pułaski

    Instytut Biologii Medycznej PAN

  32. Role of microparticles derived from platelets and cancer cells in colorectal cancer progression – how to stop them or tu...

    Call: OPUS 24 , Panel: NZ5

    Principal investigator: prof. Maria Anna Kowalska

    Instytut Biologii Medycznej PAN

  33. Epigenetic immunomodulation dependent on elements of the microbiome. Model of direct and indirect interactions of Th17 a...

    Call: OPUS 19 , Panel: NZ5

    Principal investigator: dr hab. Marcin Marek Ratajewski

    Instytut Biologii Medycznej PAN

  34. The course of COVID-19 disease in the aspect of immune response and genetic variability of the host and SARS-CoV-2

    Call: OPUS 19 , Panel: NZ6

    Principal investigator: dr hab. Edyta Teresa Paradowska

    Instytut Biologii Medycznej PAN

  35. The use of evolutionary patterns in the optimization of chemotherapy of tuberculosis

    Call: SONATA BIS 9 , Panel: NZ6

    Principal investigator: dr Alina Ewa Minias

    Instytut Biologii Medycznej PAN

  36. Factors specific for lectin pathway of complement activation in patients with haematological malignancies, receiving aut...

    Call: OPUS 6 , Panel: NZ6

    Principal investigator: dr hab. Maciej Cedzyński

    Instytut Biologii Medycznej PAN

  37. The role of IL8 in pathogenesis of tubercle bacili.

    Call: HARMONIA 1 , Panel: NZ6

    Principal investigator: prof. Jarosław Dziadek

    Instytut Biologii Medycznej PAN

  38. Identification of a novel mechanism of initiation of DNA replication in Mycobacterium smegmatis.

    Call: PRELUDIUM 1 , Panel: NZ6

    Principal investigator: Alina Ewa Minias

    Instytut Biologii Medycznej PAN

  39. Effects of receptor action of L- and D-Lactate on cervical cancer cells. Lactate modulation of cell DNA repair response ...

    Call: OPUS 2 , Panel: NZ4

    Principal investigator: dr Waldemar Wagner

    Instytut Biologii Medycznej PAN

  40. Phosphorylation of the A/B domain as the crucial mechanism involved in substrate specificity of the two isoforms (RORgam...

    Call: OPUS 10 , Panel: NZ7

    Principal investigator: dr Marcin Marek Ratajewski

    Instytut Biologii Medycznej PAN

  41. Neuromedin U, new potential regulator of colorectal cancer metastasis mechanisms.

    Call: SONATA BIS 6 , Panel: NZ3

    Principal investigator: dr Patrycja Justyna Przygodzka

    Instytut Biologii Medycznej PAN

  42. The enzymes of RNA metabolism, PAP I and PNPase, as targets for new antimycobacterial drugs and their functional charact...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Jarosław Dziadek

    Instytut Biologii Medycznej PAN

  43. Host-pathogen interplay: bacterial outer membrane vesicles as target for complement system.

    Call: OPUS 16 , Panel: NZ6

    Principal investigator: dr hab. Anna Stanisława Świerzko

    Instytut Biologii Medycznej PAN

  44. Molecular mechanisms of interplay between RORγ/RORγT receptors and cyclin-dependent kinase inhibitor (AT7519). Analysis ...

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Kaja Urszula Karaś

    Instytut Biologii Medycznej PAN

  45. Prognostic potential of neuromedin U and its receptors in the colorectal cancer, importance in the metastasis.

    Call: OPUS 21 , Panel: NZ5

    Principal investigator: dr Patrycja Justyna Przygodzka

    Instytut Biologii Medycznej PAN

  46. How is meiotic TEX12 re-activated in cancer and can we exploit this in the clinic?

    Call: SONATA BIS 13 , Panel: NZ3

    Principal investigator: dr Urszula Łucja Mcclurg

    Instytut Biologii Medycznej PAN

  47. Demonstration of the key role of vitamin B12 uptake in regulating Mycobacterium tuberculosis virulence lipids synthesis ...

    Call: SONATA BIS 14 , Panel: NZ6

    Principal investigator: dr Jakub Pawełczyk

    Instytut Biologii Medycznej PAN

  48. The effect of hypoxia on capability of mast cells to enhance proinflammatory activity of Th17 lymphocytes

    Call: OPUS 9 , Panel: NZ6

    Principal investigator: prof. Jarosław Dastych

    Instytut Biologii Medycznej PAN

  49. Genetically-determined and epigenetically-regulated Ficolin-2 insufficiency in the susceptibility of preterms to infecti...

    Call: OPUS 9 , Panel: NZ6

    Principal investigator: dr hab. Anna Stanisława Świerzko

    Instytut Biologii Medycznej PAN

  50. Risk factors for congenital and postnatal cytomegalovirus infection

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr hab. Edyta Paradowska

    Instytut Biologii Medycznej PAN

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