Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The role of mitochondria in the impairment of oligodendrocytes differentiation

2011/01/M/NZ3/02128

Keywords:

mitochondria oligodendrocytes differentiation reactive oxygen species

Descriptors:

  • NZ3_2: Cell physiology
  • NZ3_6: Cell neurobiology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Mariusz Więckowski 

Number of co-investigators in the project: 9

Call: HARMONIA 1 - announced on 2011-03-15

Amount awarded: 400 000 PLN

Project start date (Y-m-d): 2011-12-07

Project end date (Y-m-d): 2014-12-06

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. NucleoCounter system – aparat do liczenia komórek (45 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. Methods to monitor ROS production by fluorescence microscopy and fluorometry.
    Authors:
    Wojtala A, Bonora M, Malinska D, Pinton P, Duszynski J, Wieckowski MR.
    Academic press:
    Methods in Enzymology (rok: 2014, tom: 542, strony: 243-262), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/B978-0-12-416618-9.00013-3 - link to the publication
  2. Role of the c subunit of the FO ATP synthase in mitochondrial permeability transition.
    Authors:
    Bonora M, Bononi A, De Marchi E, Giorgi C, Lebiedzinska M, Marchi S, Patergnani S, Rimessi A, Suski JM, Wojtala A, Wieckowski MR, Kroemer G, Galluzzi L, Pinton P.
    Academic press:
    Cell Cycle (rok: 2013, tom: 12, strony: 674-683), Wydawca: Landes Bioscience
    Status:
    Published
    DOI:
    10.4161/cc.23599 - link to the publication
  3. Tumor necrosis factor-α impairs oligodendroglial differentiation through a mitochondria-dependent process.
    Authors:
    Bonora M, De Marchi E, Patergnani S, Suski JM, Celsi F, Bononi A, Giorgi C, Marchi S, Rimessi A, Duszyński J, Pozzan T, Wieckowski MR, Pinton P.
    Academic press:
    Cell Death & Differentiation (rok: 2014, tom: 21, strony: 1198-1208), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/cdd.2014.35 - link to the publication
  4. Guanosine diphosphate exerts a lower effect on superoxide release from mitochondrial matrix in the brains of uncoupling protein-2 knockout mice: New evidence for a putative novel function of uncoupling proteins as superoxide anion transporters.
    Authors:
    Suski JM, Shönfeld P, Bonora M, Pinton P, Więckowski MR
    Academic press:
    Biochemical and Biophysical Research Communications (rok: 2012, tom: 428, strony: 234-238), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.025 - link to the publication

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