Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Molecular mechanisms of 5-HT7R-mediated resilience in stress-related disorders

2021/41/B/NZ4/02603

Keywords:

synaptic plasticity dendritic spines 5-HT7 receptor palmitoylation

Descriptors:

  • NZ4_010:
  • NZ4_007:
  • NZ3_005:

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Jakub Mateusz Włodarczyk 

Number of co-investigators in the project: 9

Call: OPUS 21 - announced on 2021-03-15

Amount awarded: 2 802 000 PLN

Project start date (Y-m-d): 2022-01-18

Project end date (Y-m-d): 2026-01-17

Project duration:: 48 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  1. Neuronal activation affects the organization and protein composition of the nuclear speckles
    Authors:
    Szczepankiewicz A., Parobczak K., Zaręba-Kozioł M., Ruszczycki B., Bijata M., Trzaskoma P., Hajnowski G., Holm-Kaczmarek D., Włodarczyk J., Sas-Nowosielska H., Wilczyński G., Rędowicz M., Magalska A.
    Academic press:
    Biochimica et Biophysica Acta (BBA)-Molecular Cell Research (rok: 2024, tom: 1871, strony: 119829), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamcr.2024.119829 - link to the publication
  2. Restorative effect of NitroSynapsin on synaptic plasticity in an animal model of depression
    Authors:
    Wing Sze Tse, Bartłomiej Pochwat, Bernadeta Szewczyk, Paulina Misztak, Bartosz Bobula, Krzysztof Tokarski, Remigiusz Worch, Marta Czarnota-Bojarska, Stuart A Lipton, Monika Zaręba-Kozioł, Monika Bijata, Jakub Wlodarczyk
    Academic press:
    Neuropharmacology (rok: 2023, tom: 241, strony: 109729), Wydawca: Pergamon
    Status:
    Published
    DOI:
    10.1016/j.neuropharm.2023.109729 - link to the publication
  3. Altered Protein Palmitoylation as Disease Mechanism in Neurodegenerative Disorders
    Authors:
    Włodarczyk J., Bhattacharyya R., Dore K., Ho G., Martin D., Mejias R., Hochrainer K.
    Academic press:
    Journal of Neuroscience (rok: 2024, tom: 44, strony: 46036), Wydawca: Society for Neuroscience
    Status:
    Published
    DOI:
    10.1523/JNEUROSCI.1225-24.2024 - link to the publication
  4. The interplay of serotonin 5-HT1A and 5-HT7 receptors in chronic stress
    Authors:
    Bijata M., Wirth A., Włodarczyk J., Ponimaskin E
    Academic press:
    Journal of Cell Science (rok: 2024, tom: 137, strony: 46034), Wydawca: The Company of Biologists
    Status:
    Published
    DOI:
    10.1242/jcs.262219 - link to the publication
  5. Stress resilience is an active and multifactorial process manifested by structural, functional, and molecular changes in synapses
    Authors:
    Bączyńska E., Zaręba-Kozioł M., Ruszczycki B., Krzystyniak A., Wójtowicz T., Bijata K., Pochwat B., Magnowska M., Roszkowska M., Figiel-Ożóg I., Masternak J., Pytyś A., Dzwonek J., Worch R., Olszyński K., Wardak A., Szymczak P., Labus J., Radwańska K., Jahołkowski P., Hogendorf A., Ponimaskin E., Filipkowski R., Szewczyk B., Bijata M., Włodarczyk J.
    Academic press:
    Neurobiology of stress (rok: 2024, tom: 33, strony: 100683), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ynstr.2024.100683 - link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy