Does overexpression of cell adhesion molecule L1 in rats with complete spinal cord transection influences the expression of ADAM10 metalloprotease and generation of soluble forms of L1.
2012/05/N/NZ4/02241
Keywords
Descriptors
- NZ4_9: Neurobiologia systemowa
- NZ4_10: Neuroobrazowanie
Panel
NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology
Host institution
Instytut Biologii Doświadczalnej im. M. Nenckiego PAN
Voivodeship: mazowieckie
Principal investigator (from the host institution)
Number of co-investigators in the project: 3
Call
PRELUDIUM 3 – announced on 2012-03-15
- Amount awarded
- 100 000 PLN
- Project start date
- 2013-01-25
- Project end date
- 2015-01-24
- Project duration
- 24 months (the same as in the proposal)
- Project status
- Project settled
Information in the final report
Publication in academic press/journals (2)
-
The impact of training and neurotrophins on functional recovery after complete spinal cord transection: cellular and molecular mechanisms contributing to motor improvement
- Authors:
- Małgorzata Skup*, Ewelina Ziemlińska, Olga Gajewska-Woźniak, Rafał Płatek, Anna Maciejewska, and Julita Czarkowska-Bauch
- Academic press:
- Acta Neurobiologiae Experimentalis (year: 2014, volume: 74, pages: 121-141), Publisher: Nencki Institute of Experimental Biology Polish Neuroscience Society
- Status:
- Published
-
L1 overexpression in rats with complete spinal cord transection downregulates phosphacan and upregulates synaptophysin, GAP43 and Adcy1 expression
- Authors:
- Płatek R., Grycz K., Więckowska A., Czarkowska-Bauch J., Kügler S., Schachner M., Skup M.
- Academic press:
- Acta Neurobiologiae Experimentalis (year: 2013, volume: 73 (Supl. 1), pages: 34-35), Publisher: Nencki Institute of Experimental Biology Polish Neuroscience Society
- Status:
- Published
- DOI:
- link to the publication
Articles in post-conference publications (1)
-
Chronic L1 overexpression causes widespread changes in expression of molecules engaged in neuronal plasticity Adcy1, GAP-43 and synaptophysin, but not in ADAM10 - L1 shedding metalloprotease in rats with complete spinal cord transection
- Authors:
- Płatek R., Więckowska A., Grycz K., Czarkowska-Bauch J., Kügler S., Skup M.
- Conference:
- 2014 Annual Meeting of Society for Neuroscience (year: 2014, pages: x), Publisher: Society for Neuroscience
- Date:
- conference 15-19 listopada
- Status:
- Published