Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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CacyBP/SIP as a novel phosphatase in signaling pathways related to cell proliferation and differentiation

2011/03/B/NZ1/00595

Keywords:

CacyBP/SIP phosphatases MAP signaling pathway differentiation proliferation regulation of gene expression microarrays

Descriptors:

  • NZ3_1: Cell biology
  • NZ1_1: Molecular biology
  • NZ1_2: Biochemistry

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Anna Filipek 

Number of co-investigators in the project: 5

Call: OPUS 2 - announced on 2011-09-15

Amount awarded: 845 000 PLN

Project start date (Y-m-d): 2012-08-22

Project end date (Y-m-d): 2016-08-21

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Komputer z wyposażeniem (7 000 PLN)
  2. Wytrząsarka z inkubatorem (33 000 PLN)
  3. Spektrofotometr (50 000 PLN)

Information in the final report

  • Publication in academic press/journals (7)
  • Articles in post-conference publications (6)
  1. Stress-dependent changes in the CacyBP/SIP interacting protein S100A6 in the mouse brain
    Authors:
    K. Bartkowska, I. Swiatek, A. Aniszewska, E. Jurewicz, K. Turlejski, A. Filipek, R. Djavadian
    Academic press:
    PLOS one (rok: 2017, tom: 12, strony: e0169760), Wydawca: Public Library of Science
    Status:
    Published
  2. Dimerization and phosphatase activity of CacyBP/SIP: the influence of oxidative stress
    Authors:
    A. Topolska-Woś, S. Shell, E. Kilańczyk, R. Szczepanowski, W. Chazin, A. Filipek
    Academic press:
    The FASEB Journal (rok: 2015, tom: 29, strony: 1711-1724), Wydawca: Federation of American Societies for Experimental Biology
    Status:
    Published
    DOI:
    10.1096/fj.14-264770 - link to the publication
  3. MAP kinase p38 is a novel target of CacyBP/SIP phosphatase
    Authors:
    Agnieszka M. Topolska‑Wos, Sara Rosinska, Anna Filipek
    Academic press:
    Amino Acids (rok: 2017, tom: brak, strony: brak), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00726-017-2404-7 - link to the publication
  4. Regulation of CacyBP/SIP expression by NFAT1 transcription factor
    Authors:
    Beata Kądziołka, Wiesława Leśniak, Anna Filipek
    Academic press:
    Immunobiology (rok: 2016, ), Wydawca: Elsevier
    Status:
    Submitted
  5. S100A6 – focus on recent developments
    Authors:
    Leśniak W, Wilanowski T, Filipek A.
    Academic press:
    Biological Chemistry (rok: 2017, tom: nd, strony: nd), Wydawca: DE GRUYTER
    Status:
    Submitted
  6. CacyBP/SIP – structure and variety of functions
    Authors:
    A.Topolska-Woś, W. Chazin, A. Filipek
    Academic press:
    Biochem Biophys Acta - General subjects (rok: 2016, tom: 1860, strony: 79–85), Wydawca: Elsevier
    Status:
    Published
  7. Calcyclin binding protein/Siah-1 interacting protein is a Hsp90 binding chaperone
    Authors:
    A. Góral, P. Bieganowski, W. Prus, Ł. Krzemień-Ojak, B. Kądziołka, H. Fabczak, A. Filipek
    Academic press:
    PLOS one (rok: 2016, tom: 11, strony: e0156507), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0156507 - link to the publication
  1. Influence of CacyBP/SIP phosphatase on gene expression in colon cancer HCT116 cells
    Authors:
    Kądziołka B, Dębski K, Leśniak W, Filipek A.
    Conference:
    I BIO Kongres (rok: 2014, ), Wydawca: Acta Biochimica Polonica Vol. 61 (1)/Polskie Towarzystwo Biochemiczne
    Data:
    konferencja 9-12.09.2014
    Status:
    Published
  2. The CacyBP/SIP protein - a novel regulator of the Hsp90 chaperone
    Authors:
    Góral A, Bieganowski P, Prus W, Krzemień-Ojak Ł, Kądziołka B, Fabczak H, Filipek A.
    Conference:
    EMBO Conference "Cellular Signalling and Cacner Therapy" (rok: 2016, ), Wydawca: EMBO Conference
    Data:
    konferencja 27-31.05.2016
    Status:
    Published
  3. Regional and cellular distribution of CacyBP/SIP target, S100A6, in the mouse brain and its response to stress
    Authors:
    Bartkowska K, Turlejski K, Swiatek I, Jurewicz E, Filipek A, Djavadian R.
    Conference:
    10th FENS Forum of Neuroscience (rok: 2016, ), Wydawca: FENS
    Data:
    konferencja 2-6.07.2016
    Status:
    Published
  4. The influence of NFAT transcription factor on CacyBP/SIP gene expression
    Authors:
    Kądziołka B, Leśniak W, Filipek A.
    Conference:
    FEBS-EMBO Meeting (rok: 2014, ), Wydawca: FEBS Journal 281/Wiley Online Library
    Data:
    konferencja 30.08-04.09.2014
    Status:
    Published
  5. Expression of CacyBP/SIP gene in colon cancer HCT116 and neuroblastoma NB2a cells
    Authors:
    Kądziołka B, Leśniak W, Filipek A.
    Conference:
    40th FEBS Congres (rok: 2015, ), Wydawca: FEBS Journal Vol. 282/Wiley Online Library
    Data:
    konferencja 4-9.07.2015
    Status:
    Published
  6. Studies on the regulation of CacyBP/SIP gene expression
    Authors:
    Kądziołka B, Leśniak W, Filipek A.
    Conference:
    48 Zjazd PTBioch, Toruń (rok: 2013, ), Wydawca: Acta Biochimica Polonica Vol. 60 (1)/Polskie Towarzystwo Biochemiczne
    Data:
    konferencja 2-5.09.2013
    Status:
    Published