Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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The role of Fragile X Mental Retardation Protein in the local translation of Matrix Metalloproteinase 9 in neurons.

2013/08/M/NZ4/00650

Keywords:

FMRP Fragile X syndrom local translation in neurons MMP-9

Descriptors:

  • NZ3_5: Molecular neurobiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Magdalena Dziembowska 

Number of co-investigators in the project: 4

Call: HARMONIA 4 - announced on 2012-12-15

Amount awarded: 638 400 PLN

Project start date (Y-m-d): 2013-09-23

Project end date (Y-m-d): 2016-09-22

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (2)
  1. The Fragile X mental retardation protein regulates matrix metalloproteinase 9 mRNA at synapses.
    Authors:
    Aleksandra Janusz, Jacek Miłek, Małgorzata Perycz, Laura Pacini, Claudia Bagni, Leszek Kaczmarek, and Magdalena Dziembowska
    Academic press:
    Journal of Neuroscience (rok: 2013, tom: 33(46), strony: 18234–18241), Wydawca: Society for Neuroscience
    Status:
    Published
    DOI:
    10.1523/JNEUROSCI.2207-13.2013 - link to the publication
  2. miR-132 Regulates Dendritic Spine Structure by Direct Targeting of Matrix Metalloproteinase 9 mRNA
    Authors:
    Magdalena Jasi ń ska, Jacek Mi ł ek, Iwona A. Cymerman, Szymon Łę ski, Leszek Kaczmarek and Magdalena Dziembowska
    Academic press:
    Molecular Neurobiology (rok: 2015, tom: 42245, strony: 45303), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12035-015-9383-z - link to the publication