Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Role of autophagy in chemoresistance of glioblastoma stem-like cells

2011/03/B/NZ3/04453

Keywords:

autophagy cancer stem cells glioblastoma chemoresistance

Descriptors:

  • NZ3_8: Stem cell biology
  • NZ3_3: Apoptosis
  • NZ3_1: Cell biology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Iwona Ciechomska 

Number of co-investigators in the project: 4

Call: OPUS 2 - announced on 2011-09-15

Amount awarded: 550 000 PLN

Project start date (Y-m-d): 2012-09-13

Project end date (Y-m-d): 2015-09-12

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. aparat i zasilacz do elektoforezybiałkowej oraz transferu białek (10 000 PLN)
  2. wirówka osobista MiniSpin na probówki typu eppendorf (5 000 PLN)
  3. JuLi-fluoresencyjny analizator komórek (40 000 PLN)

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (8)
  • Book publications / chapters in book publications (1)
  1. Glioblastoma Stem-like Cells - Isolation, Biology and Mechanisms of Chemotherapy Resistance
    Authors:
    Iwona Anna Ciechomska, Marta Kocyk, Bozena Kaminska
    Academic press:
    Current Signal Transduction Therapy (rok: 2013, tom: Vol. 8, No. 3, strony: 256-267), Wydawca: Bentham Science Publishers
    Status:
    Published
    DOI:
    10.2174/1574362409666140206223501 - link to the publication
  1. The effects of selected inhibitors of histone modifying enzyme on autophagy in glioma stem cells
    Authors:
    Ciechomska Iwona, Przanowski Piotr, Kocyk Marta, Jackl Judyta, Kaminska Bozena
    Conference:
    ECDO 2014 – 22nd Euroconference on Apoptosis, Cell Death & Rejuvenation (rok: 2014, ), Wydawca: ECDO 2014
    Data:
    konferencja 1-4.10.2014
    Status:
    Published
  2. Epigenetic regulation of autophagy in glioma stem cells
    Authors:
    Ciechomska Iwona, Przanowski Piotr, Kocyk Marta, Jackl Judyta, Kaminska Bozena
    Conference:
    Brain Tumors from biology to therapy (rok: 2014, ), Wydawca: Brain Tumors 2014
    Data:
    konferencja 26-28.06.2014
    Status:
    Published
  3. Influence of epigenetic inhibitors on glioblastoma stem-like cells
    Authors:
    Ciechomska Iwona, Przanowski Piotr, Kocyk Marta, Jackl Judyta, Kaminska Bozena
    Conference:
    Chemical Approaches to Targeting Drug Resistance in Cancer Stem Cells, COST Action CM1106, 2nd Working Group Meeting (rok: 2014, ), Wydawca: EU COST CMST Action CM1106
    Data:
    konferencja 27-28.03.2014
    Status:
    Published
  4. The role of autophagy in response of glioma stem like cells to chemotherapy
    Authors:
    Ciechomska Iwona, Kocyk Marta, Kaminska Bozena
    Conference:
    Chemical Approaches to Targeting Drug Resistance in Cancer Stem Cells, COST Action CM1106, 2nd Working Group Meeting, (rok: 2013, ), Wydawca: COST Action CM1106
    Data:
    konferencja 19-20.09.2013
    Status:
    Published
  5. BIX-01294, an inhibitor of histone methyltransferase, induces autophagy and stimulates differentiation of glioblastoma stem-like cells
    Authors:
    Ciechomska Iwona, Przanowski Piotr, Jackl Judyta, Kaminska Bozena
    Conference:
    Autophagy signalling and progression in health and disease (rok: 2015, ), Wydawca: EMBO
    Data:
    konferencja 9-12.09.2015
    Status:
    Published
  6. Glioma stem like cells-isoloation, biology and determinants of chemoresistance
    Authors:
    Ciechomska Iwona, Kocyk Marta, Kaminska Bozena
    Conference:
    Brain Tumor 2013 (rok: 2013, ), Wydawca: Brain Tumor 2013
    Data:
    konferencja 23-24.05.2013
    Status:
    Published
  7. The effect of BIX01294, an inhibitor of histone methyltransferase, on the outcome of autophagy in glioblastoma initiating cells
    Authors:
    Ciechomska Iwona, Przanowski Piotr, Jackl Judyta, Kaminska Bozena
    Conference:
    Frontiers in Stem Cells & Cancer (rok: 2015, ), Wydawca: EMBO/EMBL
    Data:
    konferencja 29-31.03.2015
    Status:
    Published
  8. BIX01294, an inhibitor of histone methyltransferase, induces autophagy in glioblastoma initiating cells
    Authors:
    Ciechomska Iwona, Przanowski Piotr, Jackl Judyta, Kaminska Bozena
    Conference:
    Implementation of the knowledge of cell death (rok: 2015, ), Wydawca: ICDO
    Data:
    konferencja 28-30.05.2015
    Status:
    Published
  1. Autophagy in Glioma Cells
    Authors:
    Iwona Anna Ciechomska, Aleksandra Ellert-Miklaszewska, Bozena Kaminska
    Book:
    Glioma Cell Biology (rok: 2014, ), Wydawca: Springer
    Status:
    Published

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