Search results

1. Obtaining of new quinoline derivatives with potential activity for serotonin receptors and inhibition of serotonin reupt…

Principal investigator: Przemysław Paweł Taciak

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Call: PRELUDIUM 5, Panel: NZ7

2. The role of serotonin in ghrelin-induced melatonin secretion in sheep.

Principal investigator: prof. Dorota Anna Zięba-Przybylska

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Hodowli i Biologii Zwierząt

Call: OPUS 3, Panel: NZ4

3. Effect of therapy with selective serotonin reuptake inhibitors and physical exercise on blood brain barrier permeability…

Principal investigator: Marta Anna Małkiewicz

Gdański Uniwersytet Medyczny, Wydział Nauk o Zdrowiu z Instytutem Medycyny Morskiej i Tropikalnej

Call: PRELUDIUM 17, Panel: NZ5

4. The influence of perinatal exposure to selective serotonin reuptake inhibitors on the structure and functions of mice do…

Principal investigator: prof. Grzegorz Władysław Hess

Instytut Farmakologii PAN

Call: OPUS 14, Panel: NZ4

5. Impact of combined therapy of non-steroidal anti-inflammatory drugs and selective serotonin reuptake inhibitors on oxida…

Principal investigator: dr hab. Piotr Gałecki

Uniwersytet Medyczny w Łodzi, Wydział Wojskowo-Lekarski; Klinika Psychiatrii Dorosłych

Call: OPUS 3, Panel: NZ5

6. Targeting the serotonin 5-HT7 receptor in a search for new strategies of mental disorders treatment

Principal investigator: Patryk Pyka

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 22, Panel: NZ7

7. Development of a group of non-basic ligands of serotonin receptor 5-HT7, derivatives of 2-(6-oxo-3-phenyl-1,6-dihydropyr…

Principal investigator: dr Sabina Marta Podlewska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: SONATINA 2, Panel: NZ7

8. Searching for the new lead structures for 5-HT7 serotonin receptor ligands with increased metabolic stability.

Principal investigator: Sabina Marta Podlewska

Instytut Farmakologii PAN

Call: HARMONIA 7, Panel: NZ7

9. Changes in neurogenesis during withdrawal from nicotine self-administration in rats - role of serotonin (5-HT)2C recepto…

Principal investigator: dr Magdalena Joanna Zaniewska

Instytut Farmakologii PAN

Call: OPUS 9, Panel: NZ4

10. Development of a tool for automatic evaluation of complexes of ligands with serotonin receptors based on the application…

Principal investigator: Sabina Marta Podlewska

Instytut Farmakologii PAN

Call: PRELUDIUM 5, Panel: NZ2

11. Probing the selectivity of zinc allosteric modulation in various serotonin receptor subtypes

Principal investigator: Grzegorz Marek Satała

Instytut Farmakologii PAN

Call: PRELUDIUM 3, Panel: NZ7

12. Combination of FAAH inhibition with action via serotonin 5-HT6 receptor as pioneering approach to fight with Alzheimer D…

Principal investigator: Kinga Maria Czarnota-Łydka

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 21, Panel: NZ7

13. First-in-class dual biased agonists of serotonin 5-HT1A and dopamine D2 receptors – an innovative approach in the search…

Principal investigator: prof. Marcin Roman Kołaczkowski

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 21, Panel: NZ7

14. Novel hybrid 5-HT6 serotonin receptor and SERT transporter ligands as a therapeutic perspective of behavioural and cogni…

Principal investigator: dr Agata Siwek

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: SONATA 14, Panel: NZ7

15. Anilide derivatives of long-chain cyclic amines as multifunctional serotonin receptors ligands and phosphodiesterase 7 i…

Principal investigator: dr Agnieszka Wioleta Jankowska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 13, Panel: NZ7

16. The determination of ADME-Tox in vitro for potential CNS-drug candidates acting as potent and selective ligands of serot…

Principal investigator: Annamaria Teresa Lubelska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 11, Panel: NZ7

17. Effect of paroxetine and risperidone on the heterodimerization of dopamine D2 and serotonin 5-HT1A receptor in the conte…

Principal investigator: dr Magdalena Anna Kolasa

Instytut Farmakologii PAN

Call: PRELUDIUM 3, Panel: NZ7

18. In the search for active compounds among ligands of serotonin, particularly 5-HT7, and dopamine receptors, with potentia…

Principal investigator: prof. Anna Małgorzata Wesołowska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 1, Panel: NZ4

19. Synthesis and biological evaluation of pyrrolidine-2,5-dione derivatives as potential antidepressant agents.

Principal investigator: dr Andrzej Józef Chodkowski

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Call: OPUS 5, Panel: NZ7

20. AMOTL1 functions in the dopaminergic and serotonergic systems in the brain

Principal investigator: dr hab. Tomasz Jacek Prószyński

Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

Call: OPUS 28, Panel: NZ3

21. Anti-neuroinflammatory and antidepressant activities of mycelial in vitro cultures of selected edible mushrooms enriched…

Principal investigator: Jan Patryk Lazur

Uniwersytet Jagielloński

Call: PRELUDIUM 23, Panel: NZ7

22. Brain cytochrome P450 as a new target for the treatment of neurological and psychiatric diseases. Studies with human neu…

Principal investigator: prof. Władysława Anna Daniel

Instytut Farmakologii PAN

Call: OPUS 23, Panel: NZ7

23. Electrochemical analysis of neurobiologically relevant analytes

Principal investigator: dr Emilia Katarzyna Witkowska-Nery

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Call: SONATA 16, Panel: ST4

24. Mechanisms determining predatory behavior: insights from an experimental evolution on bank vole

Principal investigator: dr Edyta Teresa Sadowska

Uniwersytet Jagielloński, Wydział Biologii

Call: OPUS 20, Panel: NZ8

25. Expression and function of Regulator of G Protein Signaling (RGS) proteins in physiological and pathophysiological condi…

Principal investigator: dr hab. Maciej Stawnisław Sałaga

Uniwersytet Medyczny w Łodzi

Call: SONATA 16, Panel: NZ7

26. New 5-HT6 receptor ligands from the group of sulfonamide derivatives of cyclic arylguanidines in the treatment of gliobl…

Principal investigator: dr Przemysław Patryk Zaręba

Politechnika Krakowska im. Tadeusza Kościuszki, Wydział Inżynierii i Technologii Chemicznej

Call: PRELUDIUM 19, Panel: NZ7

27. Searching for the molecular bases of mephedrone-induced biphasic response to social interactions in rats

Principal investigator: dr Olga Iga Wronikowska-Denysiuk

Uniwersytet Medyczny w Lublinie, Wydział Nauk Medycznych

Call: PRELUDIUM 19, Panel: NZ7

28. Interspecies metabolic engineering as a tool to investigate immune functions of plant specialized metabolites.

Principal investigator: prof. Paweł Bednarek

Instytut Chemii Bioorganicznej PAN

Call: OPUS 18, Panel: NZ1

29. Thymol-derived 1,3,5-triazines, the non-indole and non-sulfone 5-HT6 receptor ligands, as a starter in search for an inn…

Principal investigator: prof. Jadwiga Handzlik

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 16, Panel: NZ7

30. The role of halogen bonding in interaction of ligands with SERT.

Principal investigator: dr Jakub Staroń

Instytut Farmakologii PAN

Call: SONATA 11, Panel: NZ7

31. Pharmacological properties and neurotoxicity of novel NBOMe derivatives

Principal investigator: prof. Krystyna Czesława Gołembiowska

Instytut Farmakologii PAN

Call: OPUS 11, Panel: NZ7

32. Magnetic Resonance Spectroscopy Evaluation of Brain Metabolites Following Microbiotic Diet

Principal investigator: prof. Grzegorz Jan Stanisz

Uniwersytet Medyczny w Lublinie, Wydział Lekarski

Call: OPUS 9, Panel: NZ4

33. Dysfunctions in the metabolic pathways of the serotonergic system during development of Autism Spectrum Disorders (ASD)

Principal investigator: Kacper Krzysztof Ptaszek

Uniwersytet Gdański, Wydział Biologii

Call: PRELUDIUM 8, Panel: NZ4

34. Unusual 5-HT6 receptor ligands

Principal investigator: prof. Andrzej Jacek Bojarski

Instytut Farmakologii PAN

Call: OPUS 7, Panel: NZ7

35. Neurochemical properties and biological activity of synthetic cathinones (beta-ketoamphetamines) - the psychostimulant "…

Principal investigator: prof. Jolanta Barbara Zawilska

Uniwersytet Medyczny w Łodzi, Wydział Farmaceutyczny

Call: OPUS 7, Panel: NZ7

36. Inhibition of activity tryptophan hydroxylase-1 - the new conception in the treatment of mineral and bone disorders in c…

Principal investigator: prof. Krystyna Pawlak

Uniwersytet Medyczny w Białymstoku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Call: OPUS 5, Panel: NZ7

37. The influence of the serotonergic system on the regulation of liver CYP activity in hepatocellular carcinoma

Principal investigator: dr Marta Ewa Kot

Instytut Farmakologii PAN

Call: SONATA 4, Panel: NZ4

38. The group III metabotropic glutamate receptors as a target for future antypsychotic drugs

Principal investigator: prof. Andrzej Pilc

Instytut Farmakologii PAN

Call: MAESTRO 3, Panel: NZ7

39. Orexinergic, glutamatergic and serotoninergic control of oscillations in the hippocampal formation in vitro.

Principal investigator: Paulina Dominika Kaźmierska

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska; Katedra Neurobiologii

Call: PRELUDIUM 1, Panel: NZ4

40. Targeted in vitro differentiation of neural progenitor cells and its potential in the reconstruction of monoaminergic in…

Principal investigator: prof. Urszula Sławińska

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: OPUS 28, Panel: NZ4

41. "I like to move it, move it" – molecular dynamics-driven optimization of ligand residence time as an opportunity to impr…

Principal investigator: dr hab. Sabina Marta Podlewska

Instytut Farmakologii PAN

Call: OPUS 25, Panel: NZ7

42. Traizine 5-HT6 receptor ligands - new perspective for therapy of current civilization CNS-diseases

Principal investigator: dr hab. Jadwiga Handzlik

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 9, Panel: NZ7

43. Halogen bonding - the role and significance in interactions of ligands with class A GPCRs

Principal investigator: dr Rafał Kurczab

Instytut Farmakologii PAN

Call: SONATA 8, Panel: NZ7

44. Behavioral and biochemical evaluation of mephedrone's action and interaction with other psychoactive drugs

Principal investigator: prof. Grażyna Biała

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny z Oddziałem Analityki Medycznej

Call: OPUS 6, Panel: NZ7

45. Cooperative involvement of serotonergic signaling and extracellular matrix in synaptic plasticity underlying the pathoge…

Principal investigator: dr hab. Jakub Mateusz Włodarczyk

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: HARMONIA 3, Panel: NZ3

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