Projects funded by the NCN

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45 projects found matching your search criteria :

  1. Targeted in vitro differentiation of neural progenitor cells and its potential in the reconstruction of monoaminergic in...

    Call: OPUS 28 , Panel: NZ4

    Principal investigator: prof. Urszula Sławińska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  2. AMOTL1 functions in the dopaminergic and serotonergic systems in the brain

    Call: OPUS 28 , Panel: NZ3

    Principal investigator: dr hab. Tomasz Jacek Prószyński

    Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

  3. Anti-neuroinflammatory and antidepressant activities of mycelial in vitro cultures of selected edible mushrooms enriched...

    Call: PRELUDIUM 23 , Panel: NZ7

    Principal investigator: Jan Patryk Lazur

    Uniwersytet Jagielloński

  4. Targeting the serotonin 5-HT7 receptor in a search for new strategies of mental disorders treatment

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Patryk Pyka

    Uniwersytet Jagielloński, Collegium Medicum

  5. "I like to move it, move it" – molecular dynamics-driven optimization of ligand residence time as an opportunity to impr...

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: dr hab. Sabina Marta Podlewska

    Instytut Farmakologii PAN

  6. Brain cytochrome P450 as a new target for the treatment of neurological and psychiatric diseases. Studies with human neu...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: prof. Władysława Anna Daniel

    Instytut Farmakologii PAN

  7. Combination of FAAH inhibition with action via serotonin 5-HT6 receptor as pioneering approach to fight with Alzheimer D...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Kinga Maria Czarnota-Łydka

    Uniwersytet Jagielloński, Collegium Medicum

  8. First-in-class dual biased agonists of serotonin 5-HT1A and dopamine D2 receptors – an innovative approach in the search...

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Marcin Roman Kołaczkowski

    Uniwersytet Jagielloński, Collegium Medicum

  9. Electrochemical analysis of neurobiologically relevant analytes

    Call: SONATA 16 , Panel: ST4

    Principal investigator: dr Emilia Katarzyna Witkowska-Nery

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  10. Mechanisms determining predatory behavior: insights from an experimental evolution on bank vole

    Call: OPUS 20 , Panel: NZ8

    Principal investigator: dr Edyta Teresa Sadowska

    Uniwersytet Jagielloński, Wydział Biologii

  11. Expression and function of Regulator of G Protein Signaling (RGS) proteins in physiological and pathophysiological condi...

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr hab. Maciej Stawnisław Sałaga

    Uniwersytet Medyczny w Łodzi

  12. New 5-HT6 receptor ligands from the group of sulfonamide derivatives of cyclic arylguanidines in the treatment of gliobl...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: dr Przemysław Patryk Zaręba

    Politechnika Krakowska im. Tadeusza Kościuszki, Wydział Inżynierii i Technologii Chemicznej

  13. Searching for the molecular bases of mephedrone-induced biphasic response to social interactions in rats

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: dr Olga Iga Wronikowska-Denysiuk

    Uniwersytet Medyczny w Lublinie, Wydział Nauk Medycznych

  14. Interspecies metabolic engineering as a tool to investigate immune functions of plant specialized metabolites.

    Call: OPUS 18 , Panel: NZ1

    Principal investigator: dr hab. Paweł Bednarek

    Instytut Chemii Bioorganicznej PAN

  15. Effect of therapy with selective serotonin reuptake inhibitors and physical exercise on blood brain barrier permeability...

    Call: PRELUDIUM 17 , Panel: NZ5

    Principal investigator: Marta Anna Małkiewicz

    Gdański Uniwersytet Medyczny, Wydział Nauk o Zdrowiu z Instytutem Medycyny Morskiej i Tropikalnej

  16. Thymol-derived 1,3,5-triazines, the non-indole and non-sulfone 5-HT6 receptor ligands, as a starter in search for an inn...

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Jadwiga Handzlik

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  17. Novel hybrid 5-HT6 serotonin receptor and SERT transporter ligands as a therapeutic perspective of behavioural and cogni...

    Call: SONATA 14 , Panel: NZ7

    Principal investigator: dr Agata Siwek

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  18. Development of a group of non-basic ligands of serotonin receptor 5-HT7, derivatives of 2-(6-oxo-3-phenyl-1,6-dihydropyr...

    Call: SONATINA 2 , Panel: NZ7

    Principal investigator: dr Sabina Marta Podlewska

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  19. The influence of perinatal exposure to selective serotonin reuptake inhibitors on the structure and functions of mice do...

    Call: OPUS 14 , Panel: NZ4

    Principal investigator: prof. Grzegorz Władysław Hess

    Instytut Farmakologii PAN

  20. Anilide derivatives of long-chain cyclic amines as multifunctional serotonin receptors ligands and phosphodiesterase 7 i...

    Call: PRELUDIUM 13 , Panel: NZ7

    Principal investigator: dr Agnieszka Wioleta Jankowska

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  21. The role of halogen bonding in interaction of ligands with SERT.

    Call: SONATA 11 , Panel: NZ7

    Principal investigator: dr Jakub Staroń

    Instytut Farmakologii PAN

  22. The determination of ADME-Tox in vitro for potential CNS-drug candidates acting as potent and selective ligands of serot...

    Call: PRELUDIUM 11 , Panel: NZ7

    Principal investigator: Annamaria Teresa Lubelska

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  23. Pharmacological properties and neurotoxicity of novel NBOMe derivatives

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: prof. Krystyna Czesława Gołembiowska

    Instytut Farmakologii PAN

  24. Searching for the new lead structures for 5-HT7 serotonin receptor ligands with increased metabolic stability.

    Call: HARMONIA 7 , Panel: NZ7

    Principal investigator: Sabina Marta Podlewska

    Instytut Farmakologii PAN

  25. Magnetic Resonance Spectroscopy Evaluation of Brain Metabolites Following Microbiotic Diet

    Call: OPUS 9 , Panel: NZ4

    Principal investigator: prof. Grzegorz Jan Stanisz

    Uniwersytet Medyczny w Lublinie, Wydział Lekarski

  26. Changes in neurogenesis during withdrawal from nicotine self-administration in rats - role of serotonin (5-HT)2C recepto...

    Call: OPUS 9 , Panel: NZ4

    Principal investigator: dr Magdalena Joanna Zaniewska

    Instytut Farmakologii PAN

  27. Traizine 5-HT6 receptor ligands - new perspective for therapy of current civilization CNS-diseases

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: dr hab. Jadwiga Handzlik

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  28. Dysfunctions in the metabolic pathways of the serotonergic system during development of Autism Spectrum Disorders (ASD)

    Call: PRELUDIUM 8 , Panel: NZ4

    Principal investigator: Kacper Krzysztof Ptaszek

    Uniwersytet Gdański, Wydział Biologii

  29. Halogen bonding - the role and significance in interactions of ligands with class A GPCRs

    Call: SONATA 8 , Panel: NZ7

    Principal investigator: dr Rafał Kurczab

    Instytut Farmakologii PAN

  30. Unusual 5-HT6 receptor ligands

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: prof. Andrzej Jacek Bojarski

    Instytut Farmakologii PAN

  31. Neurochemical properties and biological activity of synthetic cathinones (beta-ketoamphetamines) - the psychostimulant "...

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: prof. Jolanta Barbara Zawilska

    Uniwersytet Medyczny w Łodzi, Wydział Farmaceutyczny

  32. Behavioral and biochemical evaluation of mephedrone's action and interaction with other psychoactive drugs

    Call: OPUS 6 , Panel: NZ7

    Principal investigator: prof. Grażyna Biała

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny z Oddziałem Analityki Medycznej

  33. Synthesis and biological evaluation of pyrrolidine-2,5-dione derivatives as potential antidepressant agents.

    Call: OPUS 5 , Panel: NZ7

    Principal investigator: dr Andrzej Józef Chodkowski

    Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  34. Development of a tool for automatic evaluation of complexes of ligands with serotonin receptors based on the application...

    Call: PRELUDIUM 5 , Panel: NZ2

    Principal investigator: Sabina Marta Podlewska

    Instytut Farmakologii PAN

  35. Inhibition of activity tryptophan hydroxylase-1 - the new conception in the treatment of mineral and bone disorders in c...

    Call: OPUS 5 , Panel: NZ7

    Principal investigator: prof. Krystyna Pawlak

    Uniwersytet Medyczny w Białymstoku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  36. Obtaining of new quinoline derivatives with potential activity for serotonin receptors and inhibition of serotonin reupt...

    Call: PRELUDIUM 5 , Panel: NZ7

    Principal investigator: Przemysław Paweł Taciak

    Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  37. The influence of the serotonergic system on the regulation of liver CYP activity in hepatocellular carcinoma

    Call: SONATA 4 , Panel: NZ4

    Principal investigator: dr Marta Ewa Kot

    Instytut Farmakologii PAN

  38. Cooperative involvement of serotonergic signaling and extracellular matrix in synaptic plasticity underlying the pathoge...

    Call: HARMONIA 3 , Panel: NZ3

    Principal investigator: dr hab. Jakub Mateusz Włodarczyk

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  39. The group III metabotropic glutamate receptors as a target for future antypsychotic drugs

    Call: MAESTRO 3 , Panel: NZ7

    Principal investigator: prof. Andrzej Pilc

    Instytut Farmakologii PAN

  40. Effect of paroxetine and risperidone on the heterodimerization of dopamine D2 and serotonin 5-HT1A receptor in the conte...

    Call: PRELUDIUM 3 , Panel: NZ7

    Principal investigator: dr Magdalena Anna Kolasa

    Instytut Farmakologii PAN

  41. Impact of combined therapy of non-steroidal anti-inflammatory drugs and selective serotonin reuptake inhibitors on oxida...

    Call: OPUS 3 , Panel: NZ5

    Principal investigator: dr hab. Piotr Gałecki

    Uniwersytet Medyczny w Łodzi, Wydział Wojskowo-Lekarski; Klinika Psychiatrii Dorosłych

  42. Probing the selectivity of zinc allosteric modulation in various serotonin receptor subtypes

    Call: PRELUDIUM 3 , Panel: NZ7

    Principal investigator: Grzegorz Marek Satała

    Instytut Farmakologii PAN

  43. The role of serotonin in ghrelin-induced melatonin secretion in sheep.

    Call: OPUS 3 , Panel: NZ4

    Principal investigator: prof. Dorota Anna Zięba-Przybylska

    Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Hodowli i Biologii Zwierząt

  44. In the search for active compounds among ligands of serotonin, particularly 5-HT7, and dopamine receptors, with potentia...

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: prof. Anna Małgorzata Wesołowska

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  45. Orexinergic, glutamatergic and serotoninergic control of oscillations in the hippocampal formation in vitro.

    Call: PRELUDIUM 1 , Panel: NZ4

    Principal investigator: Paulina Dominika Kaźmierska

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska; Katedra Neurobiologii

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