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Information on the principal investigator and host institution

Information of the project and the call

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The role of serotonin in ghrelin-induced melatonin secretion in sheep.

2012/05/B/NZ4/02408

Keywords:

ghrelin melatonin sheep serotonin

Descriptors:

  • NZ4_8: Neuroendocrinology
  • NZ4_11: Metabolism
  • NZ4_2: Physiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Hodowli i Biologii Zwierząt

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Dorota Zięba-Przybylska 

Number of co-investigators in the project: 6

Call: OPUS 3 - announced on 2012-03-15

Amount awarded: 697 158 PLN

Project start date (Y-m-d): 2013-02-13

Project end date (Y-m-d): 2015-08-12

Project duration:: 30 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (18)
  1. Influence of season and nutritional status on the direct effects of leptin, orexin-A and ghrelin on LH and GH secretion in the ovine pituitary explant model.
    Authors:
    K. Kirsz, M. Szczesna, K. Dudek, P.M. Bartlewski, D.A. Zieba
    Academic press:
    Domestic Animal Endocrinology (rok: 2014, tom: 48, strony: 69-76), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.domaniend.2014.02.005 - link to the publication
  2. Cross-talk between leptin, ghrelin and orexins in the central nervous system of seasonal animals – a review.
    Authors:
    Kirsz K., Szczęsna M., Borsuk A., Zięba D.A.
    Academic press:
    Annals of Animal Science (rok: 2017, tom: 17, strony: 337-350), Wydawca: De Gruyter Publishers
    Status:
    Published
    DOI:
    10.1515/aoas-2016-0070 - link to the publication
  3. Photoperiod influences the effects of ghrelin and serotonin receptor agonist on growth hormone and prolactin secretion in sheep.
    Authors:
    Zieba DA, Kirsz K, Szczesna M, Molik E, Romanowicz K, Misztal T.
    Academic press:
    Journal of Neurology and Neurophysiology (rok: 2015, tom: 6, strony: 45298), Wydawca: OMICS International
    Status:
    Published
    DOI:
    10.4172/2155-9562.1000301 - link to the publication
  4. Effects of ghrelin on nocturnal melatonin secretion in sheep: An in vitro and in vivo approach.
    Authors:
    Kirsz K., Szczęsna M., Molik E., Zięba D.A.
    Academic press:
    Journal of Animal Science (rok: 2017, tom: 95, strony: 4101-4112), Wydawca: American Society of Animal Science
    Status:
    Published
    DOI:
    10.2527/jas2017.17372017 - link to the publication
  1. Agonist and antagonist of the 5-HT2B/2C receptor and ghrelin activate intracellular signal cascades responsible for melatonin biosynthesis in the ovine pineal gland.
    Authors:
    Kirsz K., Szczesna M., Zieba D.A.
    Conference:
    International Conference on Biotechnology and Welfare in Animal Science with a session on 7th PoultryDays (rok: 2016, ), Wydawca: Uniwersytet Rolniczy im. H. Kołłataja w Krakowie
    Data:
    konferencja 23-24 czerwca
    Status:
    Published
  2. Ghrelin regulates nocturnal melatonin secretion by controlling arylalkylamine-N-Acetyl-Transferase (AA-NAT) protein expression in sheep pineal gland.
    Authors:
    Zieba D., Szczesna M., Kirsz K.
    Conference:
    49th Annual Metting of Society for the Study of Reproduction: Systems Biology of Reproduction (rok: 2016, ), Wydawca: Society for the Study of Reproduction
    Data:
    konferencja 16-20 lipca
    Status:
    Published
  3. Interplay of Ghrelin and the 5-HT2C/1B Serotonin Receptor Agonist in the Regulation of Melatonin Secretion in Ewes.
    Authors:
    K. Kirsz, M. Szczesna, D. Zieba.
    Conference:
    FASEB Conference - Federation of American Societies for Experimental Biology: Melatonin Biology- Actions and Therapeutics (rok: 2015, ), Wydawca: FASEB
    Data:
    konferencja Lipiec 19-24
    Status:
    Published
  4. Funckja greliny i receptora serotoniny 5-HT2C w wydzielaniu hormonu wzrostu w zależności od długości dnia i statusużywieniowego owiec
    Authors:
    Zieba D.A., Kirsz K., Szczęsna M., Bartlewski PM., Romanowicz K.
    Conference:
    VII Zjazd TBR oraz II Sympozjum Szkoleniowe Medycyny Rozrodu i Endokrynologii Ginekologicznej (rok: 2014, ), Wydawca: Towarzystwo Biologii Rozrodu
    Data:
    konferencja 11-13 września
    Status:
    Published
  5. Interakcje pomiędzy greliną i receptorem serotoniny 5-HT2C, jako nowy mechanizm regulacji wydzielania melatoniny uzależniony od fotoperiodu i statusu energetycznego owiec.
    Authors:
    Kirsz K., Szczęsna M., Lorens J., Mikrut J., Mróz B., Nowakowski P., Zieba DA
    Conference:
    VII Zjazd TBR oraz II Sympozjum Szkoleniowe Medycyny Rozrodu i Endokrynologii Ginekologicznej (rok: 2014, ), Wydawca: Towarzystwo Biologii Rozrodu
    Data:
    konferencja 11-13 września
    Status:
    Published
  6. Seasonal effects of central leptin infusion on secretion of melatonin and SOCS-3 gene expression in ewes.
    Authors:
    Szczesna M., Molik E., Kirsz K., Zieba D.A.
    Conference:
    FASEB Conference - Federation of American Societies for Experimental Biology: Melatonin Biology- Actions and Therapeutics (rok: 2013, ), Wydawca: FASEB
    Data:
    konferencja 7-12. 07. 2013
    Status:
    Published
  7. The role of ghrelin and serotonin in the secretion of growth hormone and prolactin in sheep.
    Authors:
    Grzywacz A., Kirsz K.,Szczęsna M., Molik E., Zieba D.A.
    Conference:
    IV Zimowa Szkoła Towarzystwa Biologii Rozrodu, Central and Local Regulations of Reproductive Processes (rok: 2016, ), Wydawca: Towarzystwo Biologii Rozrodu
    Data:
    konferencja 3-5 luty
    Status:
    Published
  8. Examination of the Role of the 5-HT2C Receptor in the Interactions Between Ghrelin and Melatonin in Sheep.
    Authors:
    Zieba D.A., Kirsz K., Szczesna M., Molik E.
    Conference:
    47th Annual Meeting of the Society for the Study of Reproduction, Grand Rapids, USA (rok: 2014, ), Wydawca: SSR
    Data:
    konferencja 17.07. – 23.07.
    Status:
    Published
  9. Examination of the role of ghrelin in the regulation of TPH1 and AA-NAT protein expression in the ovine pineal gland.
    Authors:
    Kirsz K., Szczęsna M., Zięba D.A.
    Conference:
    48th Annual Meeting Society for the Study of Reproduction Evolution of sex" (rok: 2015, ), Wydawca: Society for the Study of Reproduction
    Data:
    konferencja 18-22 czerwiec
    Status:
    Published
  10. Ghrelin Acts at the Ovine Pineal Gland to Modulate Melatonin Secretion: the Role of Photoperiod.
    Authors:
    Kirsz K., Szczesna M., Zieba D.A.
    Conference:
    47th Annual Meeting of the Society for the Study of Reproduction, Grand Rapids, USA (rok: 2014, ), Wydawca: SSR
    Data:
    konferencja 17.07. – 23.07.
    Status:
    Published
  11. Oddziaływanie greliny i receptora serotoniny 5-HT2C na wydzielanie prolaktyny w zależności od długości dnia i statusu żywieniowego owiec.
    Authors:
    Szczęsna M., Kirsz K., Bartlewski PM., Romanowicz K., Zieba DA
    Conference:
    VII Zjazd TBR oraz II Sympozjum Szkoleniowe Medycyny Rozrodu i Endokrynologii Ginekologicznej (rok: 2014, ), Wydawca: Towarzystwo Biologii Rozrodu
    Data:
    konferencja 11-13 września
    Status:
    Published
  12. Seasonal plasticity of brain - the use of sheep model to study reproductive processes.
    Authors:
    D.A. Zieba, M. Szczesna, K. Kirsz, E. Molik
    Conference:
    •the 2nd Joined Polish-German Conference on Reproductive Medicine, 46th Annual Conference of Physiology and Pathology of Reproduction, 38th Joint Conference on Veterinary and Human Reproductive Medicine (rok: 2013, ), Wydawca: ELSEVIER
    Data:
    konferencja 27.02-1.03.
    Status:
    Published
  13. Cross-Talk between ghrelin and serotonin in the regulation of GH and PRL secretion in ewes.
    Authors:
    Zięba D.A., Kirsz K., Szczęsna M., Molik E.
    Conference:
    48th Annual Meeting Society for the Study of Reproduction Evolution of sex" (rok: 2015, ), Wydawca: Society for the Study of Reproduction
    Data:
    konferencja 18-22 czerwiec
    Status:
    Published
  14. The Role of the Serotonin Receptor Agonist (m-CPP) and Day-Length in the Cross-Talk Between Ghrelin and Melatonin in Sheep.
    Authors:
    M. Szczesna, K. Kirsz, D. A. Zieba.
    Conference:
    FASEB Conference - Federation of American Societies for Experimental Biology: Melatonin Biology- Actions and Therapeutics (rok: 2015, ), Wydawca: FASEB
    Data:
    konferencja 19-14 lipca
    Status:
    Published
  15. Ghrelin Regulates Nightly Melatonin Secretion From Sheep Pineal Gland In A Tph1-Independent Manner: An In Vitro Study.
    Authors:
    Kirsz K., Szczęsna M., Zięba D.A.
    Conference:
    13th International Congress of the Polish Neuroscience Society (rok: 2017, ), Wydawca: Acta Neurobiol Exp 2017, 77: I–CXLII
    Data:
    konferencja 28-31 sierpnia
    Status:
    Published
  16. Ghrelin regulates the nocturnal melatonin secretion through controlling the arylalkylamine-N-acetyl-transferase (AA-NAT) protein expression in the sheep pineal gland.
    Authors:
    Kirsz K., Szczęsna M., Zięba D.A.
    Conference:
    IV Zimowa Szkoła Towarzystwa Biologii Rozrodu, Central and Local Regulations of Reproductive Processes" (rok: 2016, ), Wydawca: Towarzystwo Biologii Rozrodu
    Data:
    konferencja 3-5 luty
    Status:
    Published
  17. Seasonal changes in the interactions between leptin, ghrelin and orexin in sheep.
    Authors:
    Kirsz K., Szczesna M., Molik E. Zieba D.A.
    Conference:
    FASEB Conference - Federation of American Societies for Experimental Biology: Melatonin Biology- Actions and Therapeutics (rok: 2013, ), Wydawca: FASEB
    Data:
    konferencja 7-12.07.2013
    Status:
    Published
  18. The role of 52HZB/C serotonin receptor agonist in the cross-talk between ghrelin and seroton in sheep: Alterning effects of photoperiod and nutritional status.
    Authors:
    K. Kirsz, M. Szczesna. D.A. Zieba-Przybylska
    Conference:
    9th International Congress of Comparative Physiology and Biochemistry from Molecules to Macrophysiology. (rok: 2015, ), Wydawca: UJ
    Data:
    konferencja Sierpień 23-28
    Status:
    Published