Projects funded by the NCN

Determination of the molecular mechanism of BbKI peptide in regulating tissue sensitivity to insulin

Call: PRELUDIUM 24 , Panel: NZ4

Principal investigator: Nataniel Jan Stefanowski

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Metallic coatings as a response to degradation of membranes in membrane distillation: long-term studies on the mechanism...

Call: OPUS 29 , Panel: ST8

Principal investigator: prof. Marek Michał Gryta

Zachodniopomorski Uniwersytet Technologiczny w Szczecinie

Mass spectrometry for the detection of lipid A modifications as a marker of polymyxin resistance in hospital infections

Call: PRELUDIUM 24 , Panel: ST4

Principal investigator: Daria Janiszewska

Uniwersytet Mikołaja Kopernika

Understanding the co-selection mechanisms of antibiotic and heavy metal resistance during methane fermentation of sewage...

Call: OPUS 28 , Panel: NZ9

Principal investigator: dr Małgorzata Czatzkowska

Uniwersytet Warmińsko-Mazurski w Olsztynie

Evaluation of the relationship between doxorubicin resistance, epithelial-mesenchymal plasticity, and effects of selecte...

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Dominika Kunachowicz

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

Impact of cytostatic drugs present in the environment on Gram-negative bacteria: mechanisms of adaptation and implicatio...

Call: PRELUDIUM 23 , Panel: NZ9

Principal investigator: Adam Grzywaczyk

Politechnika Poznańska

Potential and mechanisms changes in antibiotic susceptibility in Listeria monocytogenes under pascalisation-induced stre...

Call: PRELUDIUM 23 , Panel: NZ9

Principal investigator: Patryk Wiśniewski

Uniwersytet Warmińsko-Mazurski w Olsztynie

Optogenetic and chemogenetic identification of brain circuits and cellular mechanisms underlying antidepressants resista...

Call: OPUS 26 , Panel: NZ7

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Mitochondria-related mechanisms of exosome biogenesis and secretion in podocytes under metabolic stress.

Call: OPUS 26 , Panel: NZ5

Principal investigator: dr Irena Audzeyenka

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Strategies to improve the efficacy of NK cells in targeting aggressive B-cell lymphomas

Call: WEAVE-UNISONO , Panel: NZ6

Principal investigator: dr Małgorzata Bobrowicz

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Development of high entropy alloys with high radiation resistance and elevated mechanical properties at high temperature...

Call: SONATA BIS 13 , Panel: ST11

Principal investigator: dr hab. Łukasz Ryszard Kurpaska

Narodowe Centrum Badań Jądrowych

Dinucleoside polyphosphates (NpnN′s) as a component of the molecular mechanism in plant response to environmental stress...

Call: OPUS 24 , Panel: NZ9

Principal investigator: dr hab. Małgorzata Pietrowska-Borek

Uniwersytet Przyrodniczy w Poznaniu, Wydział Rolnictwa, Ogrodnictwa i Biotechnologii

Mechanism of action of b-cyclocitral and its derivative in inducing flax resistance to Fusarium oxysporum infection

Call: OPUS 24 , Panel: NZ9

Principal investigator: dr Aleksandra Anna Boba

Uniwersytet Wrocławski, Wydział Biotechnologii

Targeted poloxamer micelles with selected drugs as a strategy for overcoming the mechanisms of multidrug resistance in p...

Call: PRELUDIUM BIS 4 , Panel: NZ7

Principal investigator: prof. Tomasz Adam Gośliński

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Searching for new chemical compounds inducing resistance of apple to diseases and determination of the molecular mechani...

Call: SONATA 18 , Panel: NZ9

Principal investigator: dr Artur Mikiciński

Instytut Ogrodnictwa

Molecular mechanisms underlying resistance of white lupin (Lupinus albus L.) to anthracnose

Call: OPUS 23 , Panel: NZ9

Principal investigator: dr hab. Michał Piotr Książkiewicz

Instytut Genetyki Roślin PAN

The role of Candida albicans' plasma membrane sphingolipids in the potentially new mechanism of drug resistance and in t...

Call: OPUS 22 , Panel: NZ1

Principal investigator: dr hab. Anna Janina Krasowska

Uniwersytet Wrocławski, Wydział Biotechnologii

Improving the fracture resistance of forging medium manganese steel understatic, dynamic and cyclic loading conditions b...

Call: OPUS 22 (LAP) , Panel: ST5

Principal investigator: prof. Adam Szczepan Grajcar

Politechnika Śląska, Wydział Mechaniczny Technologiczny

CRISPRi-based screening for Pseudomonas aeruginosa vulnerabilities to antibiotics

Call: SONATA 17 , Panel: NZ2

Principal investigator: dr Adam Kawałek

Instytut Biochemii i Biofizyki PAN

Nanospectroscopic imaging of native biological membranes: Is the cell membrane the key for understanding the mechanism o...

Call: SONATA BIS 11 , Panel: ST4

Principal investigator: dr Katarzyna Pogoda

Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego PAN

Molecular and functional characterisation of clubroot disease resistance mechanisms in Arabidopsis

Call: OPUS 21 , Panel: NZ9

Principal investigator: dr William Matthew Donald Truman

Instytut Genetyki Roślin PAN

Reversible senescence as a new mechanism of cancer cell resistance for chemotherapy. Analysis of the mechanism of cancer...

Call: SONATINA 5 , Panel: NZ3

Principal investigator: dr Karolina Anna Staniak

Politechnika Warszawska, Wydział Chemiczny

Novel dual CYP17A1 and AKR1C3 inhibitors for studying the mechanism of resistance in prostate cancer

Call: SONATA 16 , Panel: NZ7

Principal investigator: dr Tomasz Marcin Wróbel

Uniwersytet Medyczny w Lublinie

Study on genetic, epigenetic, transcriptomic and proteomic mechanisms modulating sheep resistance to small ruminant lent...

Call: OPUS 20 (LAP) , Panel: NZ9

Principal investigator: dr hab. Ewa Joanna Grochowska

Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

Mechanism of acquiring resistance to polyenes on the Malassezia pachydermatis model

Call: SONATA 15 , Panel: NZ7

Principal investigator: dr Urszula Czyżewska

Uniwersytet w Białymstoku, Wydział Biologii

Analysis of bacteriophage P1 lytic functions as a way to discover the mechanisms of wide dissemination of clinical bacte...

Call: PRELUDIUM 18 , Panel: NZ6

Principal investigator: Agnieszka Bednarek

Instytut Biochemii i Biofizyki PAN

Investigation of the effectiveness and mechanisms of fungicidal activity of selected 1,3,4-thiadiazoles derivatives in i...

Call: OPUS 18 , Panel: NZ7

Principal investigator: prof. Mariusz Gagoś

Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Biologii i Biotechnologii

Elucidation of the mechanism of fat-induced liver insulin resistance

Call: OPUS 17 , Panel: NZ5

Principal investigator: dr hab. Agnieszka Urszula Błachnio-Zabielska

Uniwersytet Medyczny w Białymstoku, Wydział Lekarski z Oddziałem Stomatologii i Oddziałem Nauczania w Języku Angielskim

Identifying and overcoming mechanisms promoting resistance to venetoclax in B cell acute lymphoblastic leukemia with MLL...

Call: PRELUDIUM 16 , Panel: NZ5

Principal investigator: dr Klaudyna Paulina Fidyt

Warszawski Uniwersytet Medyczny, Wydział Lekarski

The combination of radiotherapy with imiquimod and sunitinib as a new therapeutic strategy overcoming some of the tumor ...

Call: SONATA 14 , Panel: NZ5

Principal investigator: dr Magdalena Jarosz-Biej

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Dissecting of the novel mechanisms in multi-drug resistance associated with vault's proteins and translation initiation ...

Call: SONATA BIS 8 , Panel: NZ7

Principal investigator: dr hab. Witold Szaflarski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski II

Determination of mechanisms and critical molecular partners controlling the multidrug resistance proteins (P-gp and BCRP...

Call: OPUS 15 , Panel: NZ3

Principal investigator: dr hab. Marlena Godlewska

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO, Studium Kliniczno-Dydaktyczne

Genomic insights into the mechanisms of drug resistance, virulence and transmission of Mycobacterium tuberculosis strain...

Call: DAINA 1 , Panel: NZ6

Principal investigator: dr Tomasz Jagielski

Uniwersytet Warszawski, Wydział Biologii

Mechanisms underlying insulin resistance in patients with pulmonary arterial hypertension. The role of peroxisome prolif...

Call: SONATA BIS 7 , Panel: NZ5

Principal investigator: dr hab. Grzegorz Kopeć

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum

Evaluation of anticancer properties and molecular mechanisms of action of new hybrid molecules containing uracil skeleto...

Call: PRELUDIUM 13 , Panel: NZ3

Principal investigator: dr Angelika Agata Długosz-Pokorska

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Effectiveness of the mechanism regulating the aluminium resistance of wheat under soil drought stress.

Call: PRELUDIUM 13 , Panel: NZ9

Principal investigator: Joanna Siecińska

Instytut Agrofizyki im. Bohdana Dobrzańskiego PAN

Mechanisms mediating the induction of Growth hormone resistance in response to immune stress.

Call: PRELUDIUM 13 , Panel: NZ9

Principal investigator: Maciej Wójcik

Instytut Fizjologii i Żywienia Zwierząt im. Jana Kielanowskiego PAN

CBR1-dependent metabolism and ABCB1-dependent effux of doxorubicin - search for a novel mechanism of reversing resistanc...

Call: PRELUDIUM 13 , Panel: NZ7

Principal investigator: Kamil Tomasz Piska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Identification of epigenetic mechanisms contributing to glioma drug resistance

Call: POLONEZ 3 , Panel: NZ2

Principal investigator: dr Jakub Karol Mieczkowski

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

The role of cGMP-dependent signaling in the regulation of expression and activity of deacetylase SIRT1: a novel mechanis...

Call: OPUS 12 , Panel: NZ4

Principal investigator: dr Dorota Rogacka

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Genetic features of Reed-Sternberg cells and their interplay with macrophages in classical Hodgkin lymphoma: identificat...

Call: HARMONIA 8 , Panel: NZ5

Principal investigator: prof. Krzysztof Zbigniew Warzocha

Instytut Hematologii i Transfuzjologii

Mechanism of diffusion layers formation in multilayered clads based on light metals of increased impact resistance

Call: OPUS 11 , Panel: ST8

Principal investigator: prof. Henryk Zdzisław Paul

Instytut Metalurgii i Inżynierii Materiałowej im. Aleksandra Krupkowskiego PAN

Old drugs - new perspectives: modulation of antibiotics activity by caffeine and pentoxifylline

Call: SONATA 11 , Panel: NZ7

Principal investigator: dr Anna Woziwodzka

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Characterization of aberrant mechanisms of telomere maintenance in chronic myeloid leukemia - the role of POT1 and RAP1 ...

Call: OPUS 10 , Panel: NZ5

Principal investigator: dr Tomasz Artur Stokłosa

Warszawski Uniwersytet Medyczny, Wydział Lekarski

Role of nicotinamide N-methyltransferase (NNMT) and mitochondrial mechanisms in endothelial dysfunction

Call: OPUS 10 , Panel: NZ3

Principal investigator: prof. Krzysztof Olaf Zabłocki

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

The molecular mechanisms of pentapeptide repeat proteins action on DNA gyrase elucidated by structural biology methods

Call: POLONEZ 1 , Panel: NZ1

Principal investigator: dr Dmitry Ghilarov

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Surface carbohydrate-dependent phages select for resistant bacterial population that become more susceptible to host cle...

Call: HARMONIA 7 , Panel: NZ6

Principal investigator: prof. Zuzanna Drulis-Kawa

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Systemic Acquired Resistance (SAR) of plants against viruses: new elicitors and biological and molecular characterizatio...

Call: OPUS 9 , Panel: NZ9

Principal investigator: prof. Henryk Pospieszny

Instytut Ochrony Roślin - Państwowy Instytut Badawczy

Analysis of mechanisms of drug resistance to trastuzumab in HER2 overexpressing breast cancer based on gene expression c...

Call: PRELUDIUM 9 , Panel: NZ2

Principal investigator: Anna Maria Rusek

Uniwersytet Medyczny w Białymstoku, Wydział Lekarski z Oddziałem Stomatologii i Oddziałem Nauczania w Języku Angielskim

Dissecting mechanisms of RNA-based Stress Granules formation, their structure and role in the development of Multi-Drug ...

Call: OPUS 9 , Panel: NZ7

Principal investigator: dr hab. Witold Szaflarski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny