Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Elucidation of the mechanism of fat-induced liver insulin resistance

2019/33/B/NZ5/02055

Keywords:

Liver insulin resistance ceramide diacylglicerols mass spectrometry

Descriptors:

  • NZ5_003:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Medyczny w Białymstoku, Wydział Lekarski z Oddziałem Stomatologii i Oddziałem Nauczania w Języku Angielskim

woj. podlaskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Agnieszka Urszula Błachnio-Zabielska 

Number of co-investigators in the project: 5

Call: OPUS 17 - announced on 2019-03-15

Amount awarded: 1 814 076 PLN

Project start date (Y-m-d): 2020-03-02

Project end date (Y-m-d): 2023-03-01

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. The Role of Acyl-CoA Synthetase 1 in Bioactive Lipid Accumulation and the Development of Hepatic Insulin Resistance
    Authors:
    Piotr Zabielski, Monika Imierska, Kamila Roszczyc-Owsiejczuk, Mariusz Kuźmicki, Paweł Rogalski, Jarosław Daniluk, Agnieszka U Błachnio-Zabielska
    Academic press:
    Nutrients (rok: 2024, tom: 16, strony: 45672), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nu16071003 - link to the publication
  2. The Influence of Physical Activity on the Bioactive Lipids Metabolism in Obesity-Induced Muscle Insulin Resistance
    Authors:
    Monika Imierska, Adam Kurianiuk, Agnieszka Błachnio-Zabielska
    Academic press:
    Biomolecules (rok: 2020, )
    Status:
    Published
    DOI:
    10.3390/biom10121665 - link to the publication
  3. Downregulation of CerS4 Instead of CerS2 in Liver Effectively Alleviates Hepatic Insulin Resistance in HFD Male Mice
    Authors:
    Kamila Roszczyc-Owsiejczuk, Piotr Zabielski, Monika Imierska, Karolina Pogodzińska, Patrycja Sadowska, Agnieszka Błachnio-Zabielska
    Academic press:
    Endocrinology (rok: 2024, tom: 165, strony: 45673), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1210/endocr/bqae118 - link to the publication

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