Projects funded by the NCN

Investigating the potential of protein-pectin complexes to improve the functional properties of 3D printing inks

Call: PRELUDIUM 23 , Panel: NZ9

Principal investigator: Magdalena Urszula Trusińska

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie

Determination of the dynamics of changes in protein networks interacting with selected isoforms of the protein phosphata...

Call: OPUS 26 , Panel: NZ9

Principal investigator: dr hab. Danuta Anna Babula-Skowrońska

Instytut Genetyki Roślin PAN

Targeting nucleic acid-protein complexes with small molecules using a deep-learning framework

Call: SONATINA 7 , Panel: NZ1

Principal investigator: dr Ryhor Nikalayeu

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Bunyaviral strategies to reorganize and exploit cellular translation

Call: SONATA BIS 12 , Panel: NZ1

Principal investigator: dr Piotr Gerlach

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Dynamics and evolution of specificity of TA complexes

Call: POLONEZ BIS 2 , Panel: NZ1

Principal investigator: dr Grzegorz Jan Grabe

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Asymmetrical flow field-flow fractionation for gentle isolation of lipid-based nanoparticles biomolecule corona complexe...

Call: SONATA BIS 11 , Panel: NZ7

Principal investigator: dr hab. Paulina Krystyna Skupin-Mrugalska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Deciphering the molecular mechanism of activity switch of the ubiquitin ligase CHIP

Call: PRELUDIUM 20 , Panel: NZ1

Principal investigator: Pankaj Thapa

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Living on the edge: evolutionary adaptation of substrate-recruiting subunits of the cullin-RING ubiquitin ligase complex...

Call: PRELUDIUM 20 , Panel: NZ1

Principal investigator: Natalia Anna Szulc

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Integrative methods for modeling protein-protein complexes and multimolecular assemblies

Call: SHENG 2 , Panel: NZ2

Principal investigator: dr hab. Sebastian Kmiecik

Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

Assessing protein-ligand complexes with ML/DL models trained on molecular dynamics-based descriptors.

Call: OPUS 20 , Panel: ST4

Principal investigator: dr hab. Paweł Aleksander Siedlecki

Instytut Biochemii i Biofizyki PAN

Combined experimental and theoretical studies of the catalytic activity of RPE65 enzyme using biomimetic active centre m...

Call: OPUS 20 , Panel: ST4

Principal investigator: dr hab. Adam Maciej Kubas

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Nucleotide sugar transporters as organizing centers of glycosylation-related macromolecular complexes

Call: OPUS 20 , Panel: NZ3

Principal investigator: dr Dorota Justyna Maszczak-Seneczko

Uniwersytet Wrocławski, Wydział Biotechnologii

Application of polymer nanodiscs to isolate and characterize membraneprotein complexes between mitochondrial respiratory...

Call: PRELUDIUM 19 , Panel: NZ1

Principal investigator: Milena Krajewska

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Combining Rosetta method with deeply coarse grained SURPASS model into a novel multiscale algorithm for modeling protein...

Call: OPUS 15 , Panel: ST6

Principal investigator: dr hab. Dominik Gront

Uniwersytet Warszawski, Wydział Chemii

The role of E3 ligase complexes in integration of protein homeostasis and aging.

Call: OPUS 12 , Panel: NZ3

Principal investigator: dr Wojciech Mieczysław Pokrzywa

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

In search of novel functions for SLC35A2 protein

Call: SONATA 12 , Panel: NZ3

Principal investigator: dr Dorota Justyna Maszczak-Seneczko

Uniwersytet Wrocławski, Wydział Biotechnologii

The role of protein factors that bind to the 5' non-coding region of human p53 mRNA in regulation of p53 expression at t...

Call: OPUS 11 , Panel: NZ1

Principal investigator: prof. Jerzy Henryk Ciesiołka

Instytut Chemii Bioorganicznej PAN

Self-aggregation of protein complexes: virus capsids and amyloids

Call: POLONEZ 1 , Panel: ST3

Principal investigator: dr Panagiotis Theodorakis

Instytut Fizyki PAN

Memetic algorithms for the excited ligand diffusion in condensed biological matter

Call: PRELUDIUM 10 , Panel: ST3

Principal investigator: Jakub Mateusz Rydzewski

Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Mechanisms of mitochondrial cytoprotection - identification of mitoBK channel interactions with mitochondrial proteins

Call: SONATA BIS 5 , Panel: NZ1

Principal investigator: dr Bogusz Stanisław Kulawiak

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Non-catalytic domains of the RNA-guided DNA methyltransferase DRM2

Call: OPUS 9 , Panel: NZ1

Principal investigator: dr Humberto Fernandes

Instytut Biochemii i Biofizyki PAN

Global protein docking algorithms based on the UNRES coarse-grained model

Call: PRELUDIUM 9 , Panel: ST4

Principal investigator: dr Paweł Krupa

Uniwersytet Gdański, Wydział Chemii

Structure-based dynamical models of large and complex biomolecular systems

Call: OPUS 8 , Panel: ST3

Principal investigator: prof. Marek Cieplak

Instytut Fizyki PAN

Functional analysis of SLC35A transporter family - substrate specificity and ability to interact with other proteins in ...

Call: OPUS 8 , Panel: NZ3

Principal investigator: prof. Mariusz Olczak

Uniwersytet Wrocławski, Wydział Biotechnologii

Molecular basis of amyloidogenesis - structure of conformational dynamics slected complexes of human prion protein PrPc ...

Call: OPUS 8 , Panel: ST4

Principal investigator: prof. Maciej Leszek Kozak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

Role of SWI/SNF remodeling complexes, CTCF1 protein , long non-coding RNA transcribed from BRCA1/NBR2 bidirectional prom...

Call: OPUS 6 , Panel: NZ2

Principal investigator: prof. Janusz Aleksander Siedlecki

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Structural and thermodynamic studies of complexes avidin with luminescents and metallocenes biotin derivatives

Call: PRELUDIUM 6 , Panel: ST5

Principal investigator: Paweł Strzelczyk

Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

Crystallographic investigation of mammalian serum albumins in complexes with ligands

Call: OPUS 6 , Panel: ST5

Principal investigator: dr Anna Danuta Bujacz

Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

An integrated approach to the prediction of the structures of proteins and protein complexes with the use of the coarse-...

Call: HARMONIA 5 , Panel: ST4

Principal investigator: prof. Józef Adam Liwo

Uniwersytet Gdański, Wydział Chemii

The role of the light-dependent chlorophyll biosynthesis in the regulation of the biosynthesis and assembly of pigment-p...

Call: SONATA BIS 3 , Panel: NZ3

Principal investigator: dr hab. Beata Joanna Myśliwa-Kurdziel

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Halogen Bonding in Protein-Ligand Complexes. Thermodynamics and Structural Studies on Rationally Selected Protein-Ligand...

Call: OPUS 4 , Panel: ST4

Principal investigator: prof. Jarosław Poznański

Instytut Biochemii i Biofizyki PAN

Molecular basis of carnitine transporters OCTN2 and ATB(0,+) trafficking to plasma membrane of astrocytes: The role of p...

Call: OPUS 4 , Panel: NZ3

Principal investigator: prof. Katarzyna Anna Nałęcz

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Structural study of the complexes of hydrolytic enzymes with heteroorganic substrates and substrate analogs

Call: OPUS 3 , Panel: ST4

Principal investigator: dr hab. Jarosław Błaszczyk

Centrum Badań Molekularnych i Makromolekularnych PAN

Synchrotron small angle X-ray scattering and TEM microscopy studies of Hsp90:Sgt1:Rar1 and Sgt1 TPR domain dimer complex...

Call: PRELUDIUM 3 , Panel: ST3

Principal investigator: Michał Taube

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

Assembly analysis of MAPKKK18 protein complexes: characterisation of MAPKKK18-dependent ABA signalling pathway

Call: OPUS 3 , Panel: NZ3

Principal investigator: dr Agnieszka Ludwików

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Multidomain and multimeric proteins: structural and mechanical insights

Call: OPUS 3 , Panel: NZ1

Principal investigator: dr Bartosz Jan Różycki

Instytut Fizyki PAN

Development of a new scoring function for models of protein-small molecule complexes and its use for studying the mechan...

Call: PRELUDIUM 2 , Panel: NZ2

Principal investigator: dr Irina Tuszyńska

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Structure prediction of proteins and large protein assemblies guided by low-resolution or/and sparse experimental data.

Call: SONATA 1 , Panel: NZ2

Principal investigator: dr Dominik Gront

Uniwersytet Warszawski, Wydział Chemii

Mechanostability of proteins and their complexes

Call: PRELUDIUM 1 , Panel: ST3

Principal investigator: Mateusz Kazimierz Sikora

Instytut Fizyki PAN