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Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Mechanostability of proteins and their complexes

2011/01/N/ST3/02475

Keywords:

protein stretching AFM complex rupture mechanostability

Descriptors:

  • NZ1_3: Biophysics

Panel:

ST3 - Condensed matter physics: structure, electronic properties, fluids, nanosciences, biological physics

Host institution :

Instytut Fizyki PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Mateusz Sikora 

Number of co-investigators in the project: 3

Call: PRELUDIUM 1 - announced on 2011-03-15

Amount awarded: 51 350 PLN

Project start date (Y-m-d): 2011-12-01

Project end date (Y-m-d): 2013-05-31

Project duration:: 18 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Komputer PC (5 166 PLN)
  2. Monitor (1 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  • Book publications / chapters in book publications (1)
  1. Cystine plug and other novel mechanisms of large mechanical stability in dimeric proteins
    Authors:
    M. Sikora and M. Cieplak
    Academic press:
    Phys. Rev. Lett. (rok: 2012, tom: 109, strony: 208101), Wydawca: Amercan Physical Society
    Status:
    Published
    DOI:
    10.1103/PhysRevLett.109.208101 - link to the publication
  2. Theoretical tests of the mechanical protection strategy in protein nanomechanics
    Authors:
    Mateusz Chwastyk, Angel Gomez-Sicilia, Albert Galera–Prat, Mariano Carrion-Vazquez, Mateusz Sikora, Marek Cieplak
    Academic press:
    Proteins: Structure, Function, and Bioinformatics (rok: 2013, tom: 82, strony: 717-726), Wydawca: John Wiley & Sons
    Status:
    Published
    DOI:
    10.1002/prot.24436 - link to the publication
  3. Formation of Cystine Slipknots in Dimeric Proteins
    Authors:
    Mateusz Sikora, Marek Cieplak
    Academic press:
    PLOS One (rok: 2013, tom: 8, strony: e57443), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0057443 - link to the publication
  1. Mechanical properties of TGF-β family proteins
    Authors:
    Mateusz Sikora, Carl-Philipp Heisenberg, Marek Cieplak
    Conference:
    Workshop on Biomolecules and Nanostructures 4 (rok: 2013, ), Wydawca: European Physical Society, Europhysics Conference Abstracts
    Data:
    konferencja 5-19.05
    Status:
    Published
  1. Topological features in stretching of proteins
    Authors:
    Cieplak M, Sikora M.
    Book:
    Biochemical Society Transactions (rok: 2013, tom: 41, strony: 519-522), Wydawca: Portland Press
    Status:
    Published

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