Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Functional analysis of SLC35A transporter family - substrate specificity and ability to interact with other proteins in the Golgi membrane

2014/15/B/NZ3/00372

Keywords:

SLC35A nucleotide sugar transporters glycosylation Golgi apparatus protein complexes

Descriptors:

  • NZ3_1: Cell biology
  • NZ1_2: Biochemistry
  • NZ3_2: Cell physiology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Wrocławski, Wydział Biotechnologii

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Mariusz Olczak 

Number of co-investigators in the project: 6

Call: OPUS 8 - announced on 2014-09-15

Amount awarded: 797 000 PLN

Project start date (Y-m-d): 2015-07-23

Project end date (Y-m-d): 2018-07-22

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Inkubator do hodowli tkankowych ssaczych linii komórkowych (30 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Book publications / chapters in book publications (1)
  1. Lysine at position 329 within a C-terminal dilysine motif is crucial for the ER localization of human SLC35B4
    Authors:
    Bożena Bazan, Maciej Wiktor, Dorota Maszczak-Seneczko, Teresa Olczak, Beata Kaczmarek, Mariusz Olczak
    Academic press:
    PLOS One (rok: 2018, tom: 13(11), strony: e0207521), Wydawca: PLOS
    Status:
    Published
    DOI:
    10.1371/journal.pone.0207521 - link to the publication
  2. SLC35A5 Protein—A Golgi Complex Member with Putative Nucleotide Sugar Transport Activity
    Authors:
    Paulina Sosicka, Bożena Bazan, Dorota Maszczak-Seneczko, Yauhen Shauchuk, Teresa Olczak, Mariusz Olczak
    Academic press:
    International Journal of Molecular Sciences (rok: 2019, tom: 20, strony: 276), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms20020276 - link to the publication
  3. SLC35A3 role in N-acetylglucosamine incorporation into glycoconjugates is cell-specific and largely dependent on SLC35A2
    Authors:
    Bożena Szulc, Paulina Sosicka, Dorota Maszczak-Seneczko, Edyta Skurska, Yauhen Shauchuk, Teresa Olczak, Hudson H. Freeze, Mariusz Olczak
    Academic press:
    Journal of Biological Chemistry , Wydawca: American Society for Biochemistry and Molecular Biology (United States)
    Status:
    Submitted
    DOI:
    brak - link to the publication
  4. An insight into the orphan nucleotide sugar transporter SLC35A4
    Authors:
    60.Sosicka P, Maszczak-Seneczko D, Bazan B, Shauczuk E, Kaczmarek B, Olczak M
    Academic press:
    Biochemica at Biophysica Acta - Molecular Cell Research (rok: 2017, tom: 1864, strony: 825-838), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamcr.2017.02.002 - link to the publication
  1. In situ proximity ligation assay (PLA) analysis of protein complexes formed between Golgi-resident, glycosylation-related transporters and transferases in adherent mammalian cell cultures
    Authors:
    Maszczak-Seneczko D, Sosicka P, Olczak T, Olczak M
    Book:
    Methods in Molecular Biology. Chapter: The Golgi Complex: Methods and Protocols (rok: 2016, tom: 1496, strony: 133-143), Wydawca: Springer
    Status:
    Published

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