Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Role of SWI/SNF remodeling complexes, CTCF1 protein , long non-coding RNA transcribed from BRCA1/NBR2 bidirectional promoter in folding of BRCA1 gene with topologicaly associated domains on chromosome 17.

2013/11/B/NZ2/00132

Keywords:

BRCA1 SWI/SNF CTCF

Descriptors:

  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ2_1: Molecular genetics

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Janusz Siedlecki 

Number of co-investigators in the project: 5

Call: OPUS 6 - announced on 2013-09-16

Amount awarded: 950 000 PLN

Project start date (Y-m-d): 2014-07-16

Project end date (Y-m-d): 2018-01-15

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  1. RRM2 gene expression depends on BAF180 subunit of SWISNF chromatin remodeling complex and correlates with abundance of tumor infiltrating lymphocytes in ccRCC.
    Authors:
    Szarkowska J, Cwiek P, Szymanski M, Rusetska N, Jancewicz I, Stachowiak M, Swiatek M, Luba M, Konopinski R, Kubala S, Zub R, Kucharz J, Wiechno P, Siedlecki JA, Markowicz S, Sarnowska E, Sarnowski TJ.
    Academic press:
    Am J Cancer Res. (rok: 2021, tom: 11, strony: 5965-5978), Wydawca: e-Century publishing corporation
    Status:
    Published
    DOI:
    brak - link to the publication
  2. The RoleofSWI/SNF Chromatin Remodeling Complexes inHormone Crosstalk
    Authors:
    Elzbieta Sarnowska,1 Dominika M.Gratkowska,2 Sebastian P.Sacharowski,2 Pawel Cwiek,2 Takayuki Tohge,3 Alisdair R.Fernie,3 Janusz A.Siedlecki,1 Csaba Koncz,4,5 and Tomasz J.Sarnowski2,*
    Academic press:
    Trends in Plant Science (rok: 2016, tom: 7, strony: 594-608), Wydawca: Cell Press
    Status:
    Published
    DOI:
    10.1016/j.tplants.2016.01.017 - link to the publication
  3. The BRCA1 tumor suppressor: potential long-range interactions of the BRCA1 promoter and the risk of breast cancer
    Authors:
    Beata Anna Bielinska
    Academic press:
    Journal of Translational Science (rok: 2016, tom: 3, strony: 45301), Wydawca: OAT
    Status:
    Published
    DOI:
    10.15761/JTS.1000172 - link to the publication
  1. Downregulation of BRCA1 protein in clear cell renal cellular Carcinoma
    Authors:
    E. Sarnowska, N. Rusetska, M. Szymanski, I. Jancewicz, M. Chmielarczyk, R. Konopinski, M. Leszczynski, A. Chrzan, M. Ligaj, A. Maassen, T. Sarnowski, J. Siedlecki
    Conference:
    ESMO 2017 (rok: 2017, ), Wydawca: Annals of Oncology
    Data:
    konferencja 8-12 września
    Status:
    Published

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