Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Application of polymer nanodiscs to isolate and characterize membraneprotein complexes between mitochondrial respiratory chain and potassiumchannels

2020/37/N/NZ1/01808

Keywords:

polymer nanodiscs mitochondrial respiratory chain mitoBKCa protein complexes potassium channels

Descriptors:

  • NZ1_002:

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Milena Krajewska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 19 - announced on 2020-03-16

Amount awarded: 70 000 PLN

Project start date (Y-m-d): 2021-02-01

Project end date (Y-m-d): 2022-07-31

Project duration:: 18 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (8)
  1. Methods of Measuring Mitochondrial Potassium Channels: A Critical Assessment
    Authors:
    Agnieszka Walewska, Milena Krajewska, Aleksandra Stefanowska, Aleksandra Buta, Renata Bilewicz, Paweł Krysiński, Piotr Bednarczyk, Piotr Koprowski, Adam Szewczyk
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23(3), strony: 1210), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23031210 - link to the publication
  2. Pharmacological Characterization of a Recombinant Mitochondrial ROMK2 Potassium Channel Expressed in Bacteria and Reconstituted in Planar Lipid Bilayers
    Authors:
    Milena Krajewska, Adam Szewczyk, Bogusz Kulawiak, Piotr Koprowski
    Academic press:
    Membranes (rok: 2023, tom: 13, strony: 360), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/membranes13030360 - link to the publication
  3. Interaction of ROMK2 channel with lipid kinases DGKE and AGK: Potential channel activation by localized anionic lipid synthesis
    Authors:
    Milena Krajewska; Mariusz Możajew; Sławomir Filipek; Piotr Koprowski
    Academic press:
    BBA - Molecular and Cell Biology of Lipids (rok: 2024, tom: 1869 (2), strony: 159443), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbalip.2023.159443 - link to the publication
  1. Studies on mitochondrial potassium channels: mitoKATP and mitoBKCa using polymer nanodiscs.
    Authors:
    Milena Krajewska, Adam Szewczyk, and Piotr Koproski
    Conference:
    The 5th PhD Student Conference Scientific Programme (rok: 2021, tom: The 5th PhD Student Conference, strony: 45), Wydawca: Nencki Institute of Experimental Biology PAS
    Data:
    konferencja 14-15 października 2021
    Status:
    Published
    DOI:
    brak - link to the publication
  2. Biophysical and biochemical studies on mitochondrial potassium channels using polymer nanodiscs
    Authors:
    M. Krajewska, A. Szewczyk, P. Koprowski
    Conference:
    The 20th FEBS YSF Forum Programme and Abstract Book (rok: 2021, tom: The 20th FEBS YSF Forum, strony: 79), Wydawca: The Federation of European Biochemical Societies (FEBS) in collaboration with the Croatian Society of Biochemistry and Molecular Biology and the Slovenian Biochemical Society
    Data:
    konferencja 15-18 czerwca 2021
    Status:
    Published
  3. Biophysical and biochemical studies on mitochondrial potassium channels using polymer nanodiscs
    Authors:
    M. Krajewska, A. Szewczyk, P. Koprowski
    Conference:
    Supplement: 45th FEBS Congress, Molecules of Life: Towards New Horizons, Ljubljana, Slovenia, July 3–8, 2021 (rok: 2021, tom: 45th FEBS Congress, strony: 228), Wydawca: FEBS open bio
    Data:
    konferencja 3-7 lipca 2021
    Status:
    Published
    DOI:
    10.1002/2211-5463.13205 - link to the publication
  4. Polymer nanodiscs as a tool for biophysical and biochemical studies on mitochondrial potassium channels
    Authors:
    Milena Krajewska, Adam Szewczyk, Piotr Koprowski
    Conference:
    9th Mitochondrion Abstract Book (rok: 2021, tom: 9th Mitochondrion, strony: 26), Wydawca: Sekcja Bioenergetyki Polskiego Towarzystwa Biochemicznego
    Data:
    konferencja 27 stycznia 2021
    Status:
    Published
    DOI:
    brak - link to the publication
  5. Biophysical and biochemical studies on mitochondrial potassium channels using polymer nanodiscs
    Authors:
    M. Krajewska, A. Szewczyk, P. Koprowski
    Conference:
    Supplement: 45th FEBS Congress, Molecules of Life: Towards New Horizons, Ljubljana, Slovenia, July 3–8, 2021 (rok: 2021, tom: 45th FEBS Congress, strony: 228), Wydawca: FEBS open bio
    Data:
    konferencja 3-7 lipca 2021
    Status:
    Published
    DOI:
    10.1002/2211-5463.13205 - link to the publication
  6. Studies on mitochondrial potassium channels: mitoKATP and mitoBKCa using polymer nanodiscs.
    Authors:
    Milena Krajewska, Adam Szewczyk, and Piotr Koproski
    Conference:
    The 5th PhD Student Conference Scientific Programme (rok: 2021, tom: The 5th PhD Student Conference, strony: 45), Wydawca: Nencki Institute of Experimental Biology PAS
    Data:
    konferencja 14-15 października 2021
    Status:
    Published
    DOI:
    brak - link to the publication
  7. Polymer nanodiscs as a tool for biophysical and biochemical studies on mitochondrial potassium channels
    Authors:
    Milena Krajewska, Adam Szewczyk, Piotr Koprowski
    Conference:
    9th Mitochondrion Abstract Book (rok: 2021, tom: 9th Mitochondrion, strony: 26), Wydawca: Sekcja Bioenergetyki Polskiego Towarzystwa Biochemicznego
    Data:
    konferencja 27 stycznia 2021
    Status:
    Published
    DOI:
    brak - link to the publication
  8. Biophysical and biochemical studies on mitochondrial potassium channels using polymer nanodiscs
    Authors:
    M. Krajewska, A. Szewczyk, P. Koprowski
    Conference:
    The 20th FEBS YSF Forum Programme and Abstract Book (rok: 2021, tom: The 20th FEBS YSF Forum, strony: 79), Wydawca: The Federation of European Biochemical Societies (FEBS) in collaboration with the Croatian Society of Biochemistry and Molecular Biology and the Slovenian Biochemical Society
    Data:
    konferencja 15-18 czerwca 2021
    Status:
    Published

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